Navigation Links
The hunt for a successor to lithium for bipolar disorder
Date:3/27/2013

Toxicity problems and adverse side effects when taking lithium, the mainstay medication for treating bipolar disorder, are fostering a scientific hunt for insights into exactly how lithium works in the body with an eye to developing a safer alternative. That's the topic of the cover story in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society.

Bethany Halford, C&EN senior editor, explains that lithium often is the first-line medication used to calm the highs and boost the lows of bipolar disorder, which affects about 9 million people at some point in their lives in the United States alone. Lithium has distinct advantages over the dozen or so other medications. For instance, lithium is the only medication proven effective in preventing suicide in the mania phase of bipolar disorder. Lithium also is inexpensive.

The article explains, however, that lithium also has drawbacks, with a fine line between the effective dose and the toxic dose. Side effects include thyroid problems, weight gain and, in some cases, kidney failure. In the hope of skirting lithium's limitations, scientists are trying to pinpoint exactly how lithium stabilizes mood and how it engenders those unwanted effects. The goal is development of a second-generation successor without lithium's downsides, and Halford describes how scientists are working to do so.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Giving lithium to those who need it
2. Ketamine improved bipolar depression within minutes
3. Radio Guest Karen Tyrrell to Share her Story of Bipolar Disorder and Recovery
4. Family History of Schizophrenia, Bipolar Disorder May Up Kids Risk for Autism
5. Mount Sinai finds common factors in autism spectrum disorders, schizophrenia, and bipolar disorder
6. Pregnant Women With Bipolar Disorder May Have Higher Risk of Premature Birth
7. Brain Scans Might Help Spot Risk for Bipolar Disorder
8. How do happiness and sadness circuits contribute to bipolar disorder?
9. Pitt study examines cost-effectiveness of medicare drug plans in schizophrenia and bipolar disorder
10. Family intervention improves mood symptoms in children and adolescents at risk for bipolar disorder
11. Bascom Palmer Eye Institute announces breakthrough for degenerative vision disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Planet Fitness, ... the U.S., announced today its plans to open a flagship location in Covington, LA ... the former Rooms To Go store next to Office Depot in the Holiday Square ...
(Date:10/12/2017)... ... 12, 2017 , ... The American College of Medical Informatics (ACMI) will present ... the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium ... Collen, a pioneer in the field of medical informatics, this prestigious award is presented ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. ... recently contributed a medical article to the newly revamped Cosmetic Town journal ... spotlights the hair transplant procedure known as Follicular Unit Extraction (FUE). ...
(Date:10/12/2017)... ... ... On Saturday, October 21, the Health & Wellness Center at Florida Hospital ... for the American Heart Association Heart Walk. Teams of up to 10 people can ... their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. on Saturday, ...
(Date:10/12/2017)... ... 2017 , ... In the United States, single-family home owners ... New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average is $7,000 ... property-tax rates, which contributes to the relatively lower cost of living in places ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... CHICAGO , Oct. 11, 2017  Hill-Rom Holdings, ... its Aspen Surgical facility in Las Piedras, ... surgical scalpels and blades. ... confirmed that the facility sustained minor structural damage, temporary ... Hurricane Maria. Repairs have been completed, manufacturing operations have ...
(Date:10/7/2017)... Texas , Oct. 6, 2017   Provista, ... with more than $100 billion in purchasing power, today ... news and information. The Newsroom is the ... and industry trends, infographics, expert bios, news releases, slideshows ... having access to a wealth of resources at their ...
(Date:10/4/2017)... 2017  According to the Centers for Disease Control and Prevention (CDC), ... PhysicianOne Urgent Care is helping communities across Massachusetts , ... by offering no-cost* flu shots through the end of the month. ... insurance regulations. ... get a flu shot is by the end of October, according to ...
Breaking Medicine Technology: