Navigation Links
The hunt for a successor to lithium for bipolar disorder
Date:3/27/2013

Toxicity problems and adverse side effects when taking lithium, the mainstay medication for treating bipolar disorder, are fostering a scientific hunt for insights into exactly how lithium works in the body with an eye to developing a safer alternative. That's the topic of the cover story in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society.

Bethany Halford, C&EN senior editor, explains that lithium often is the first-line medication used to calm the highs and boost the lows of bipolar disorder, which affects about 9 million people at some point in their lives in the United States alone. Lithium has distinct advantages over the dozen or so other medications. For instance, lithium is the only medication proven effective in preventing suicide in the mania phase of bipolar disorder. Lithium also is inexpensive.

The article explains, however, that lithium also has drawbacks, with a fine line between the effective dose and the toxic dose. Side effects include thyroid problems, weight gain and, in some cases, kidney failure. In the hope of skirting lithium's limitations, scientists are trying to pinpoint exactly how lithium stabilizes mood and how it engenders those unwanted effects. The goal is development of a second-generation successor without lithium's downsides, and Halford describes how scientists are working to do so.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Giving lithium to those who need it
2. Ketamine improved bipolar depression within minutes
3. Radio Guest Karen Tyrrell to Share her Story of Bipolar Disorder and Recovery
4. Family History of Schizophrenia, Bipolar Disorder May Up Kids Risk for Autism
5. Mount Sinai finds common factors in autism spectrum disorders, schizophrenia, and bipolar disorder
6. Pregnant Women With Bipolar Disorder May Have Higher Risk of Premature Birth
7. Brain Scans Might Help Spot Risk for Bipolar Disorder
8. How do happiness and sadness circuits contribute to bipolar disorder?
9. Pitt study examines cost-effectiveness of medicare drug plans in schizophrenia and bipolar disorder
10. Family intervention improves mood symptoms in children and adolescents at risk for bipolar disorder
11. Bascom Palmer Eye Institute announces breakthrough for degenerative vision disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... GlycoMark, Inc. announced today a ... the Northeast U.S. , GlycoMark is the only clinically available blood test ... a clinically proven one- to two-week measure of hyperglycemic excursions, often related to ...
(Date:4/28/2017)... ... April 28, 2017 , ... Datta Endoscopic Back ... joined the revolutionary endoscopic practice under Dr. Datta. Patel is a Board Certified ... The patented, revolutionary eDiscSculpt Technique created and used by Datta Endoscopic is unlike ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... could substantially improve drug safety and minimize the cost of development. In this ... channel inhibition using cell lines and for cardiac toxicity using induced pluripotent stem ...
(Date:4/28/2017)... ... April 28, 2017 , ... Researchers at Moffitt Cancer ... CentrePoint Data Hub in a sample of participants enrolled in an ongoing ... sleep monitoring solutions for the global scientific community. The company’s new CentrePoint Data ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... NuevaCare, a ... as diverse as Millbrae, Burlingame, and Palo Alto, is proud to announce information upgrades ... persons to bookmark and read organized content on topics such as home care (generally) ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017 /PRNewswire/ - CRH Medical Corporation (TSX: CRH) (NYSE ... Bloom Burton & Co. Healthcare Investor Conference 2017 at the Sheraton ... Edward Wright , Chief Executive Officer of the Company is scheduled ... CFO, Richard Bear and the Chairman of the Board, ... ...
(Date:4/19/2017)... MOUNTAIN VIEW, Calif. , April 19, 2017 /PRNewswire/ ... that it will release financial results for the first ... May 3, 2017.  The Company,s management team will host ... / 5:30 p.m. ET. Investors interested in ... dialing (844) 707-0665 for domestic callers or (703) 326-3030 ...
(Date:4/19/2017)... , April 19, 2017  Vanderbilt University Medical ... patients in Nashville , Tennesse have ... Esophageal Sphincter Stimulation for GERD (LESS GERD) trial. The ... provide long-term reflux control by restoring normal function to ... 65 million people in the United States ...
Breaking Medicine Technology: