Navigation Links
The genetic key to conquering cholera
Date:7/19/2013

Researchers have long understood that genetics can play a role in how susceptible people are to contracting cholera, but a team of Harvard scientists is now uncovering evidence of genetic changes that might also help protect some people from contracting the deadly disease.

Based on genetic data gathered from hundreds of people in Bangladesh, a research team made up of Harvard faculty and scientists from the Broad Institute and Massachusetts General Hospital were able to a number of areas in the genome some of which are responsible for certain immune system functions, while others are related to fluid loss that appear to be related to cholera resistance. Later tests showed genetic differences between people who had contracted the disease and those who had been exposed, but did not become ill. Their results are described in a paper published earlier this month in Science Translational Medicine.

"This study is exceptionally exciting for us because it shows the power of this approach," said Associate Professor of Organismic and Evolutionary Biology Pardis Sabeti, one of two senior co-authors of the paper. "This is the first time we've taken a genomic-wide approach to understanding cholera resistance. But it's a first step, and there is a lot of exploration to go from here. For a disease that's so ancient and widespread there's very little that's known about host immunity."

The hope, Sabeti added, is that by better understanding why some people appear to be immune, it will help in our efforts to develop vaccines and therapies, so outbreaks like those that occurred in recent years in Haiti and Africa might one-day be avoided.

"It is a very scary disease," she said. "We now have treatments with oral rehydration therapy, but it is still devastating, and in extreme cases, cholera can kill in hours."

"We also haven't been able to develop a particularly effective vaccine," added Elinor Karlsson, a Post-Doctoral Fe
'/>"/>

Contact: Peter Reuell
preuell@fas.harvard.edu
617-496-8070
Harvard University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Understanding Genetically Modified Organisms Article and Video Published by Health News Wires
2. Even healthy-looking smokers have early cell damage which destroys necessary genetic programming
3. Genetic Testing Market 2012-2016 - Global Genetic Testing Industry Share, Size,Trends, Analysis, Growth And Forecast Research Report To 2016
4. Exposure to stress even before conception causes genetic changes to offspring
5. Epigenetic changes to fat cells following exercise
6. Moms often talk to children about the results of cancer genetic testing
7. Genetics of cervical cancer raise concern about antiviral therapy in some cases
8. Moffitt Cancer Center researchers identify genetic variants predicting aggressive prostate cancers
9. Yale researchers unravel genetics of dyslexia and language impairment
10. Genetic variations may help identify best candidates for preventive breast cancer drugs
11. Mount Sinai researchers provide 1st prospective characterization of a genetic subtype of autism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... By Steven Reinberg ... -- On the same day that President Barack Obama announced ... Africa,s Ebola crisis, the World Health Organization warned Tuesday that ... infections could start doubling every three weeks. Obama said ... offer medical and logistical support to beleaguered health care facilities ...
(Date:9/17/2014)... severe maternal morbidity amongst women in Australia is ... study published today (17 September) in BJOG: ... , Australians generally enjoy high standards of living; ... exist, in particular between indigenous and non indigenous ... the independent impact of socioeconomic position on severe ...
(Date:9/17/2014)... of a perfectly poured glass of wine leads to an ... Denmark, have now developed a nanosensor that can mimic what ... measures how you experience the sensation of dryness in the ... they need to control a number of processes to bring ... in the wine bottle. An important part of the taste ...
(Date:9/17/2014)... 17, 2014 MarijuanaStock.net, a cannabis ... recently launched a “Video” section that contains important ... in the marijuana industry made available in video ... visitor is given access to numerous interviews, news ... businesses and the issues they face. , ...
(Date:9/17/2014)... Fresh off their High Times Cannabis ... support of The Silver Tour, an educational non-profit effort ... benefits of medical marijuana. , Florida Buds, a Florida ... marijuana dispensary and treatment center, donated $1,000.00 to ... launch a statewide radio campaign in advance of Election ...
Breaking Medicine News(10 mins):Health News:Obama Steps Up Aid to Fight Ebola in West Africa 2Health News:Obama Steps Up Aid to Fight Ebola in West Africa 3Health News:New study examines the impact of socioeconomic position and maternal morbidity in Australia 2Health News:New study examines the impact of socioeconomic position and maternal morbidity in Australia 3Health News:Nanoscience makes your wine better 2Health News:Nanoscience makes your wine better 3Health News:MarijuanaStock.net Adds Business News Video Section to Their Website 2Health News:Florida Buds Supports Silver Tour 2
... Therapeutics Inc. (Nasdaq CM: CRTX), a specialty pharmaceutical company ... for the respiratory and related markets, today announced that ... Vice President, General Counsel and Secretary. In this ... team and manage its legal function and corporate governance ...
... ... Drug Administration approved the use of silicone implants for breast augmentation procedures in women over ... decision capped a controversy that spanned more than a decade, and one plastic surgeon ... , ...
... , ... 1-3 December at Olympia Grand Hall, London, ... across Mainland Europe with two brand new features -- The French ... France, and The European Librarians’ Theatre which hosts sessions on topical ...
... CHARLOTTE, N.C., Nov. 12 Even with the economy still ... - and in quite a creative way. , Southeast Pain ... Dec. 3 performance of "Grease" at Ovens Auditorium and giving ... , "We are committed to supporting our patients in ...
... INDIANAPOLIS, Nov. 12 Centerplate, the hospitality ... sports stadiums, announced today with the Capital Improvement ... investigation of Lucas Oil Stadium to immediately address ... facility operates as a model of operational excellence ...
... are highlights from the November issue of Mayo ... as often as you wish. Mayo Clinic ... Reprinting is allowed for a fee. Include the following ... www.bookstore.mayoclinic.com or call toll-free for subscription ...
Cached Medicine News:Health News:Cornerstone Therapeutics Appoints General Counsel 2Health News:Cornerstone Therapeutics Appoints General Counsel 3Health News:Valencia, California, Plastic Surgeon Weighs in on Silicone Breast Implants – 3 Years After FDA Approval 2Health News:Valencia, California, Plastic Surgeon Weighs in on Silicone Breast Implants – 3 Years After FDA Approval 3Health News:Valencia, California, Plastic Surgeon Weighs in on Silicone Breast Implants – 3 Years After FDA Approval 4Health News:Online Information 2009 Exhibition Focuses on Mainland Europe 2Health News:Online Information 2009 Exhibition Focuses on Mainland Europe 3Health News:Southeast Pain Care Provides Relief and Gives Back - Creatively 2Health News:Centerplate and the Capital Improvement Board Investigating Food Safety Violations at Lucas Oil Stadium to Ensure Highest Standards Achieved and Operational Excellence 2Health News:November 2009 Mayo Clinic Women's HealthSource Highlights Reducing Cancer Risk, Tips to Reduce Flatulence and Eating Nuts for Heart Health 2Health News:November 2009 Mayo Clinic Women's HealthSource Highlights Reducing Cancer Risk, Tips to Reduce Flatulence and Eating Nuts for Heart Health 3Health News:November 2009 Mayo Clinic Women's HealthSource Highlights Reducing Cancer Risk, Tips to Reduce Flatulence and Eating Nuts for Heart Health 4Health News:November 2009 Mayo Clinic Women's HealthSource Highlights Reducing Cancer Risk, Tips to Reduce Flatulence and Eating Nuts for Heart Health 5
(Date:9/17/2014)... 2014  Soligenix, Inc. (OTCQB: SNGX) (Soligenix or ... that address unmet medical needs in the areas ... agreement has been reached with the US Food ... a pivotal, Phase 3 clinical trial evaluating its ... cutaneous T-cell lymphoma (CTCL).  SGX301 ...
(Date:9/17/2014)... LAUSANNE , Switzerland , ... part of Debiopharm Group ™ , is proud to ... ™ instrument. Debiopharm Diagnostics is a long-time ... portfolio. Idylla ™ Biocartis, fully ... designed to offer physicians fast and easy access ...
(Date:9/16/2014)... Sept. 16, 2014 This report analyzes the worldwide ... the following Product Segments: SPECT Systems (Includes SPECT and SPECT/CT ... report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... and forecasts are provided for the period 2013 through 2020. ...
Breaking Medicine Technology:Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 2Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 3Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 4Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 5Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 6Soligenix Announces FDA Clearance of Phase 3 Clinical Protocol of SGX301 in Cutaneous T-Cell Lymphoma 7Debiopharm Diagnostics Portfolio Company Biocartis Ships its First Idylla Instrument 2Global Nuclear Medicine Imaging Equipment Industry 2Global Nuclear Medicine Imaging Equipment Industry 3Global Nuclear Medicine Imaging Equipment Industry 4Global Nuclear Medicine Imaging Equipment Industry 5Global Nuclear Medicine Imaging Equipment Industry 6Global Nuclear Medicine Imaging Equipment Industry 7Global Nuclear Medicine Imaging Equipment Industry 8Global Nuclear Medicine Imaging Equipment Industry 9Global Nuclear Medicine Imaging Equipment Industry 10Global Nuclear Medicine Imaging Equipment Industry 11Global Nuclear Medicine Imaging Equipment Industry 12Global Nuclear Medicine Imaging Equipment Industry 13Global Nuclear Medicine Imaging Equipment Industry 14Global Nuclear Medicine Imaging Equipment Industry 15Global Nuclear Medicine Imaging Equipment Industry 16Global Nuclear Medicine Imaging Equipment Industry 17Global Nuclear Medicine Imaging Equipment Industry 18Global Nuclear Medicine Imaging Equipment Industry 19Global Nuclear Medicine Imaging Equipment Industry 20Global Nuclear Medicine Imaging Equipment Industry 21Global Nuclear Medicine Imaging Equipment Industry 22Global Nuclear Medicine Imaging Equipment Industry 23Global Nuclear Medicine Imaging Equipment Industry 24Global Nuclear Medicine Imaging Equipment Industry 25Global Nuclear Medicine Imaging Equipment Industry 26
... 2011 Reportlinker.com announces that a new ... catalogue: Drug Delivery in ... companies http://www.reportlinker.com/p0203542/Drug-Delivery-in-Central-Nervous-System-Diseases---technologiesmarkets-and-companies.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology ... The delivery of drugs to central nervous ...
... 30, 2011 Reportlinker.com announces that a ... its catalogue: Cardiovascular Drug ... http://www.reportlinker.com/p0203538/Cardiovascular-Drug-Delivery---technologiesmarkets-and-companies.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology ... the cardiovascular system is different from delivery ...
Cached Medicine Technology:Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 2Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 3Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 4Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 5Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 6Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 7Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 8Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 9Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 10Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 11Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 12Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies 13Cardiovascular Drug Delivery - Technologies, Markets and Companies 2Cardiovascular Drug Delivery - Technologies, Markets and Companies 3Cardiovascular Drug Delivery - Technologies, Markets and Companies 4Cardiovascular Drug Delivery - Technologies, Markets and Companies 5Cardiovascular Drug Delivery - Technologies, Markets and Companies 6Cardiovascular Drug Delivery - Technologies, Markets and Companies 7Cardiovascular Drug Delivery - Technologies, Markets and Companies 8Cardiovascular Drug Delivery - Technologies, Markets and Companies 9Cardiovascular Drug Delivery - Technologies, Markets and Companies 10Cardiovascular Drug Delivery - Technologies, Markets and Companies 11Cardiovascular Drug Delivery - Technologies, Markets and Companies 12Cardiovascular Drug Delivery - Technologies, Markets and Companies 13
... improves patient compliance, prevent skin breakdown ... user's anatomy, wicks moisture, and evenly ... shoulders and upper throacic. Fits upright ... airflow openings. Adjustable Occipital Support Strap™ ...
Wonderflex™ is a lined soft durometer silicone gel sheet. It is ideal for cushioning orthotic/prosthetic devices and offers protection from shock and sheer forces. Wonderflex can also be lamina...
... length 10" elastic binder has a variety of ... an abdominal binder for post-surgical dressings. It ... has been a loss of muscle tone. ... belt to prevent painful expansion of the chest ...
Designed to provide relief from chronic or acute back pain by unloading pressure off the lumbar discs and shifting pressure to the abdominal region...
Medicine Products: