Navigation Links
The diabetes 'breathalyzer'
Date:6/10/2013

PITTSBURGHDiabetes patients often receive their diagnosis after a series of glucose-related blood tests in hospital settings, and then have to monitor their condition daily through expensive, invasive methods. But what if diabetes could be diagnosed and monitored through cheaper, noninvasive methods?

Chemists at the University of Pittsburgh have demonstrated a sensor technology that could significantly simplify the diagnosis and monitoring of diabetes through breath analysis alone. Their findings were published in the latest issue of the Journal of the American Chemical Society (JACS).

Even before blood tests are administered, those with diabetes often recognize the condition's symptoms through their breath acetonea characteristic "fruity" odor that increases significantly during periods of glucose deficiency. The Pitt team was interested in this biomarker as a possible diagnostic tool.

"Once patients are diagnosed with diabetes, they have to monitor their condition for the rest of their lives," said Alexander Star, principal investigator of the project and Pitt associate professor of chemistry. "Current monitoring devices are mostly based on blood glucose analysis, so the development of alternative devices that are noninvasive, inexpensive, and provide easy-to-use breath analysis could completely change the paradigm of self-monitoring diabetes."

Together with his colleaguesDan Sorescu, a research physicist at the National Energy Technology Laboratory, and Mengning Ding, a Pitt graduate student studying chemistryStar used what's called a "sol-gel approach," a method for using small molecules (often on a nanoscale level) to produce solid materials. The team combined titanium dioxidean inorganic compound widely used in body-care products such as makeupwith carbon nanotubes, which acted as "skewers" to hold the particles together. These nanotubes were used because they are stronger than steel and smaller than any element of silicon-based electronics.

This method, which the researchers playfully call "titanium dioxide on a stick," effectively combined the electrical properties of the tubes with the light-illuminating powers of the titanium dioxide. They then created the sensor device by using these materials as an electrical semiconductor, measuring its electrical resistance (the sensor's signal).

The researchers found the sensor could be activated with light to produce an electrical charge. This prompted them to "cook" the "skewers" in the sensor under ultraviolet light to measure acetone vaporswhich they found were lower than previously reported sensitivities.

"Our measurements have excellent detection capabilities," said Star. "If such a sensor could be developed and commercialized, it could transform the way patients with diabetes monitor their glucose levels."

The team is currently working on a prototype of the sensor, with plans to test it on human breath samples soon.


'/>"/>

Contact: B. Rose Huber
rhuber@pitt.edu
412-624-4356
University of Pittsburgh
Source:Eurekalert

Related medicine news :

1. How a cancer drug leads to diabetes
2. Heart failure patients with diabetes may benefit from higher glucose levels
3. Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study
4. Mouse Study Hints at New Path for Diabetes Treatment
5. Common Plastics Chemical Might Boost Diabetes Risk
6. Weight-Loss Surgery Beat Drugs for Cutting Diabetes in Very Obese
7. Naturopathic care can improve blood sugar, mood in diabetes
8. Cellular pathway linked to diabetes, heart disease
9. Diabetes Groups Issue New Guidelines on Blood Sugar
10. Value of Metformin, Insulin Combo for Type 2 Diabetes Questioned
11. Xenotransplantation as a therapy for type 1 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... 10 Best Water is excited ... bottled water brand owners that topped the list as a result of their commitment ... The premier brand was Tibet 5100, a top notch water company that specializes in ...
(Date:2/10/2016)... ... 10, 2016 , ... Intalere’s 2016 Executive Forum, taking place ... the country’s top healthcare executives to share insights on transformational strategies to drive ... is the provider-centric perspective, experience, expertise and strategy shared by the participants,” said ...
(Date:2/10/2016)... ... February 10, 2016 , ... Armune BioScience signed ... their network of laboratory service centers across the country. Launched in April of 2015, ... the detection of prostate cancer. Apifiny order volume exceeded 3,000 tests in 2015. Primary ...
(Date:2/10/2016)... ... 10, 2016 , ... A national ergonomics pioneer , ... event March 9-11, 2016. Hosted by Ohio's Bureau of Worker's Compensation, the expo ... longest running and largest worker's compensation event in Ohio, organizers of the safety ...
(Date:2/10/2016)... Jacksonville, Florida (PRWEB) , ... ... ... of North Florida – 1 UNF Drive, Jacksonville, FL 32224, February 26th: ... $30, February 27th: Elite Division - Time: 7:00pm – 10:00pm | Ticket ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... WINDSOR, ON , Feb. 10, 2016 /PRNewswire/ ... Perry , has announced the release of an ... This is a revolutionary breakthrough in the treatment ... environmental radiation exposure. It will assist in the ... are present. It will also protect only the ...
(Date:2/10/2016)... 10, 2016  Silicon Biosystems Menarini Inc., a ... help uncover the biological complexities of disease at ... developer of innovative technologies for genomics research, today ... at enabling translational researchers to obtain high-quality sequencing ... tumor and normal cells in an optimized and ...
(Date:2/10/2016)... -- Until recently, the options for reducing the appearance of ... approved the non-invasive Coolsculpting treatment, which removes fat cells ... in 2010 for the abdomen and this approval was ... this add-on approval, the experts at Laser Therapy Health ... CoolMini, to address smaller areas of fat. ...
Breaking Medicine Technology: