Navigation Links
The concussed brain at work: fMRI study documents brain activation during concussion recovery
Date:8/19/2013

For the first time, researchers have documented irregular brain activity within the first 24 hours of a concussive injury, as well as an increased level of brain activity weeks latersuggesting that the brain may compensate for the injury during the recovery time.

The findings are published in the September issue of the Journal of the International Neuropsychological Society.

Thomas Hammeke, PhD, professor of psychiatry and behavioral medicine at the Medical College of Wisconsin, is the lead author. Collaborators at the Cleveland Clinic; St. Mary's Hospital in Enid, Okl.; the University of North Carolina; Franklin College in Franklin, Ind., and the Marshfield Clinic in Marshfield, Wis., co-authored the paper.

To study the natural recovery from sports concussion, 12 concussed high school football athletes and 12 uninjured teammates were evaluated at 13 hours and again at seven weeks following concussive injury.

The concussed athletes showed the expected postconcussive symptoms, including decreased reaction time and lowered cognitive abilities. Imaging via fMRI (functional magnetic resonance imaging) showed decreased activity in select regions of the right hemisphere of the brain, which suggests the poor cognitive performance of concussion patients is related to that underactivation of attentional brain circuits.

Seven weeks post-injury, the concussed athletes showed improvement of cognitive abilities and normal reaction time. However, imaging at that time showed the post-concussed athletes had more activation in the brain's attentional circuits than did the control athletes.

"This hyperactivation may represent a compensatory brain response that mediates recovery," said Dr. Hammeke. "This is the first study to demonstrate that reversal in activation patterns, and that reversal matches the progression of symptoms from the time of the injury through clinical recovery."

"Deciding when a concussed player should return to the playing field is currently an inexact science," said Dr. Stephen Rao, director of the Schey Center for Cognitive Neuroimaging at the Cleveland Clinic and a senior author. "Measuring changes in brain activity during the acute recovery period can provide a scientific basis for making this critical decision."

Each year, an estimated 3.8 million people sustain a traumatic brain injury (TBI). TBI is a contributing factor to a third of all injury-related deaths in the United States. More than three-quarters of the TBI's that occur are concussions or other forms of mild TBI, many of which may go undiagnosed.


'/>"/>

Contact: Maureen Mack
mmack@mcw.edu
414-955-4744
Medical College of Wisconsin
Source:Eurekalert

Related medicine news :

1. New MR analysis technique reveals brain tumor response to anti-angiogenesis therapy
2. St. Onge Company Named 2013 Great Chain Partner by SupplyChainBrain
3. Autistic kids who best peers at math show different brain organization, Stanford/Packard study shows
4. Remembering to remember supported by 2 distinct brain processes
5. Unlock The Brain’s Fundamental Nutrition and Necessities with Dr. Bob, “The Drugless Doctor”
6. Donated 2014 Ford Shelby Raises $500,000 for Brain Injury Association of America
7. Theres life after radiation for brain cells
8. Inaugural Barn Bash a Celebration of Life for 16 Year Brain Cancer Survivor in West Linn Oregon
9. Brain Monitoring Market to reach $1.63 Billion - 2017 at a 8.06% CAGR - New Report by MarketsandMarkets
10. Brain dopamine may serve as a risk marker for alcohol use disorders
11. Alcoholism could be linked to a hyper-active brain dopamine system
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... 2017 , ... The Boulevard is honored to host Shriners and Masons Children’s ... located in the Main West Entrance of The Boulevard (in front of JCPenney). ... necessary and each child with a parent or guardian will be photographed for free ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... News Advisory/Interview ... Choice has helped score a major victory in Europe for public health and the ... , Based on rigorous scientific research and the overwhelming support of European citizens, ...
(Date:3/23/2017)... ... March 23, 2017 , ... “Wounded Woman Be Ye Healed-Passing On A Legacy”: ... A Legacy” is the creation of published author, Desiree M Webb, a registered nurse, ... She has been happily married to her husband, Paul, for over twenty-nine years. ...
(Date:3/23/2017)... ... March 23, 2017 , ... Ogden ... innovative patient - centric payment system, to expand its focus on patient care ... patient financial experience. , “At Ogden Clinic, we are working to become ...
(Date:3/23/2017)... ... ... Trainer”: an electrifying and suspenseful gunslinger novel with a twist. “The Trainer” is ... an enthusiasm for action and adventure stories. , Published by Christian Faith ... at the thirty-three notches that lined the edges of the wooden grip plates of ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... , March 23, 2017 ... Enterprises Limited, anuncia el nombramiento de Stuart ... una plataforma de servicios integrados completa para su ... un cargo clave en el crecimiento y ejecución ... será responsable de impulsar todas las actividades de ...
(Date:3/23/2017)... Merrimack Pharmaceuticals, Inc. (NASDAQ: MACK ) ... a Phase 1 study of MM-310 in solid tumors. ... novel taxane and targets the EphA2 receptor, a protein ... major tumor types, including prostate, ovarian, bladder, gastric, pancreatic ... study is an important step in evaluating MM-310,s safety ...
(Date:3/23/2017)... March 23, 2017 /PRNewswire/ - Medicure Inc. ("Medicure" ... specialty pharmaceutical company, is pleased to announce that ... approval from the U.S. Food and Drug Administration ... ("ANDA") for tetrabenazine tablets in the 12.5 mg ... is a generic equivalent of the branded product ...
Breaking Medicine Technology: