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The breathing lifeline that comes at a price
Date:6/3/2008

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The challenge for researchers investigating ventilator-associated lung injury has been how to effectively monitor and observe the lungs of patients while on life-support. It is impossible to get monitoring equipment into the lungs themselves and x-rays are unable to provide the level of definition and clarity needed.

The 432,000 research project, funded by the Engineering and Physical Sciences Research Council (EPSCR) will see Dr Hardman working with control engineer Dr Declan Bates at The University of Leicester to produce believable computer models of lungs. These could be used to test a range of different uses of the ventilator, for example, varying the amount of oxygen supplied to the patient or the number of breaths per minute provided by the machine.

Real-life data collected in the autumn by researchers from patients on the Intensive Care Unit at Nottingham's Queen's Medical Centre will be used to create the computer models. The results of that work will then be taken out into clinical trials.

Dr Hardman said: "We plan to recreate a population of patients with a variety of illnesses and injuries which will allow us to look at the different permutations of treatment for those. Eventually this could lead to computer management of ventilators which will provide the optimum treatment with the least risk of injury."


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Contact: Emma Thorne
emma.thorne@nottingham.ac.uk
44-011-595-15793
University of Nottingham
Source:Eurekalert

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