Navigation Links
The blood-brain barrier: A misunderstood key to finding life-saving cures to brain disease
Date:12/18/2007

ST. LOUIS -- An international team of scientists that includes a Saint Louis University researcher suggest several strategies to propel research for treatments of brain diseases that include multiple sclerosis, Alzheimers disease, obesity and stroke in the January issue of the Lancet Neurology.

Their review article, which focuses on surmounting obstacles posed by the blood-brain barrier (BBB), is available in an early online edition of the prestigious medical journal on Dec. 17.

The blood-brain barrier is a gate-keeping system of cells that protects the brain from toxins and lets in nutrients. Because it passes no judgment on which foreign substances are there to treat diseases and which are penetrating the brain to do harm, it locks all of them out. That makes getting drugs into the brain where they can do their work in treating brain diseases difficult.

A big part of our work is raising the awareness about the blood-brain barrier as an intimate part of the disease process, said William A. Banks, M.D., professor of geriatrics and pharmacological and physiological science at Saint Louis University School of Medicine, and a member of the research team.

You cant get drugs into the brain or understand brain disease without understanding the blood-brain barrier, which is among our most significant recommendations for future research.

The blood-brain barrier is woefully misunderstood, said Banks, who also is a staff physician at Veterans Affairs Medical Center in St. Louis.

The general theme of our review article is the blood-brain barrier is not a brick wall but a regulating interface between the brain and the rest of the body. Look at the brain as an island, where all raw materials have to be imported. The blood-brain barrier is the shipping and communications system that connects the island (the brain) to the rest of the world (the body).

Sometimes the blood-brain barrier lets in things that it shoul
'/>"/>

Contact: Nancy Solomon
solomonn@slu.edu
314-977-8017
Saint Louis University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
3. New MRI finding sheds light on multiple sclerosis disease progressio
4. High and mighty: first common height gene identified by researchers behind obesity gene finding
5. Scientists, physicians present latest findings in personalized cancer treatment and prevention
6. Health psychologists discuss latest research findings
7. Incidental findings found when radiologists take a broader look at renal MRA
8. First significant genetic finding in severe PMS, or PMDD
9. Chair of U.S. Preventive Services Task Force Pledges to Recommend Re-evaluation of Recent Glaucoma Findings
10. The Organic Trade Association Hails Preliminary Research Findings Showing Nutritional Benefits of Organic Products
11. Key findings for all veterans seen in depression and suicide study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2015)... Adenna, Inc ., worldwide supplier of high-quality, ... the launch of Enov8 (pronounced “innovate”), one ... (PE) and approved by the U.S. FDA for patient ... The Enov8 glove might look like the PE gloves ... our proprietary formula and production technology brings to life ...
(Date:5/26/2015)... MN (PRWEB) May 26, 2015 Learning ... product line, Nutrition Education Cards . These cards ... Featuring engaging photography and simple, easy-to-read text, these new ... educators . They offer practical nutrition tips and suggestions ... Current titles available are: , + MyPlate: Eat for ...
(Date:5/26/2015)... Many sexy cocktail dresses inspired by ... collections recently. Now, TheCelebrityDresses.com is offering great discounts ... 70% off. The company aims to help ladies ... of dollars on valuable, trendy formal outfits. , ... fashion special occasion dresses. Their dresses are popular ...
(Date:5/26/2015)... U.S. Food and Drug Administration (FDA) ... are extensive and can be difficult to understand. ... device companies comply with FDA regulations, compiled a list ... FDA requirements. , 1. Start researching early. ... be a lengthy process depending on the classification of ...
(Date:5/26/2015)... (PRWEB) May 26, 2015 Carl W. ... Pinehurst Surgical Center in Pinehurst, N.C. have launched a ... surgery patients about chronic sinusitis and the benefits of ... can be used to determine if someone is a ... about symptoms and other factors that can contribute to ...
Breaking Medicine News(10 mins):Health News:Enov8® Exam Glove by Adenna® Approved by U.S. FDA 2Health News:Learning ZoneXpress Introduces New Educational Resource for WIC, SNAP-Ed, and EFNEP 2Health News:Cocktail Dresses Inspired by Celebrities on Sale at TheCelebrityDresses.com 2Health News:FDA Medical Device Regulations: Top 10 Tips for Marketing a Device in the USA 2Health News:FDA Medical Device Regulations: Top 10 Tips for Marketing a Device in the USA 3Health News:FDA Medical Device Regulations: Top 10 Tips for Marketing a Device in the USA 4Health News:Pinehurst Surgical Sinus Center Launches Pinehurst Balloon Sinuplasty Website 2
... (AMS), which affects about half of those ascending to heights ... pulmonary or cerebral edema. ,The interest of the general ... past 25 years. This change is partly due to media ... In spite of these apparent changes, it is unknown whether ...
... deadly bird flu since it is still rampant in the region, ... ,"I think countries in this part of the world have ... it, the virus is still circulating," said Shigeru Omi, WHO's regional ... We remain concerned. We must avoid human transmission," he told reporters ...
... patients who have already gone blind in one eye ... and Therapeutics Bulletin (DTB). ,But that is ... (NICE), the body responsible for guiding the NHS on ... (Lucentis) and pegaptanib (Macugen) are licensed in the UK ...
... Biotechnology Co., Ltd. announced that a team led by ... completed a study to assess clinical efficacy, safety, ... for patients with peripheral vascular disease of the lower ... research and treatments for ataxia, cerebral palsy, spinal cord ...
... Those involved in biological weapons programs should be logically liable ... it seems to have happened in US and the Centers ... research laboratory at Texas A&M University to stop all work ... investigating reports of lab workers infected with the category B ...
... personnel involved in the Iraqi invasion of 2003 have ... published ahead of print in Occupational and Environmental Medicine. ... combat to pierce armoured vehicles, and spontaneously combusts on ... breathed in or eaten/drunk in contaminated food/water. ...
Cached Medicine News:Health News:Acute Mountain Sickness may Lead to Pulmonary or Cerebral Edema 2Health News:Bird Flu in Asia Still High Risk Says WHO Official 2Health News:Draft National Policy on Sight-saving Drugs unacceptable 2Health News:Adult Stem Cells Show Promise for Peripheral Vascular Disease 2Health News:Bio-defense Lab Ordered Shut Down as Researchers Get Infected 2Health News:Bio-defense Lab Ordered Shut Down as Researchers Get Infected 3Health News:Bio-defense Lab Ordered Shut Down as Researchers Get Infected 4
(Date:5/26/2015)... 26, 2015 Cellular testing ... ,What,s the future of technologies for screening cells? ... 2015. Stay ahead there for data, benefiting your ... results, R&D, opportunities and revenue forecasts. ... you what,s possible for cell-based assays ...
(Date:5/26/2015)... LONDON , May 26, 2015 ... Access Initiative, Inc. (CHAI) announced today that Aurobindo Pharma ... dolutegravir 50mg, for Tentative Approval, to the Food and ... is the first ANDA for a generic version of ... Tivicay® (dolutegravir) for sale in the United ...
(Date:5/26/2015)... NEW YORK , May 26, 2015 /PRNewswire/ ... and Flatiron Health today announced a ... cloud-based, electronic health record (EHR), data analytics and decision ... Together, the companies will build upon their existing respective ... radiation oncology and data analytics product suite. ...
Breaking Medicine Technology:Cell-Based Assays: World Industry and Market Prospects 2015-2025 2Cell-Based Assays: World Industry and Market Prospects 2015-2025 3Cell-Based Assays: World Industry and Market Prospects 2015-2025 4Cell-Based Assays: World Industry and Market Prospects 2015-2025 5Cell-Based Assays: World Industry and Market Prospects 2015-2025 6Cell-Based Assays: World Industry and Market Prospects 2015-2025 7ViiV Healthcare and CHAI Collaboration Delivers Second Milestone With First Filing With the FDA of Generic Dolutegravir by Aurobindo Pharma for the Treatment of HIV 2ViiV Healthcare and CHAI Collaboration Delivers Second Milestone With First Filing With the FDA of Generic Dolutegravir by Aurobindo Pharma for the Treatment of HIV 3ViiV Healthcare and CHAI Collaboration Delivers Second Milestone With First Filing With the FDA of Generic Dolutegravir by Aurobindo Pharma for the Treatment of HIV 4ViiV Healthcare and CHAI Collaboration Delivers Second Milestone With First Filing With the FDA of Generic Dolutegravir by Aurobindo Pharma for the Treatment of HIV 5ViiV Healthcare and CHAI Collaboration Delivers Second Milestone With First Filing With the FDA of Generic Dolutegravir by Aurobindo Pharma for the Treatment of HIV 6ViiV Healthcare and CHAI Collaboration Delivers Second Milestone With First Filing With the FDA of Generic Dolutegravir by Aurobindo Pharma for the Treatment of HIV 7Varian Medical Systems and Flatiron Health to Develop Next Generation of Cloud-based Oncology Software 2Varian Medical Systems and Flatiron Health to Develop Next Generation of Cloud-based Oncology Software 3Varian Medical Systems and Flatiron Health to Develop Next Generation of Cloud-based Oncology Software 4
... – Intercell AG (VSE,“ICLL”) has been informed by ... results of a Phase I study involving,in total ... of different doses of the Staphylococcus aureus,vaccine. , ... conserved protein,antigen discovered by Intercell’s Antigen Identification,Program (AIP®) ...
... for New Combination, PARSIPPANY, N.J., May 21, ... amlodipine besylate with the angiotensin,receptor blocker olmesartan ... and diastolic blood pressure in,patients with hypertension, ... of Hypertension's Twenty-Second Annual Scientific,Meeting and Exposition ...
Cached Medicine Technology:Staphylococcus aureus vaccine development on track ? safe and,immunogenic in Phase I clinicaltrials 2Staphylococcus aureus vaccine development on track ? safe and,immunogenic in Phase I clinicaltrials 3Amlodipine and Olmesartan Study Results Released; Late Breaker,Presented at American Society of Hypertension Twenty-Second Annual,Scientific Meeting (ASH 2007) 2Amlodipine and Olmesartan Study Results Released; Late Breaker,Presented at American Society of Hypertension Twenty-Second Annual,Scientific Meeting (ASH 2007) 3
... pedicle screw insertion assembly incorporates slotted ... construct locking. The PathFinder MIS System ... the pedicle screw insertion assembly incorporates ... insertion. The evolutionary Pathfinder MIS pedicle ...
Kerrison (Spurling) Laminectomy Rongeur. 15 cm - 6, thick footplate, large handle, 90 up-cutting, 2 mm wide....
Micro-Kerrison Laminectomie Rongeur and Stella Punch, golden springs, with ejector. 18 cm - 7 1/8, very delicate, narrow footplate, small handle, 40 up-cutting, jaws 2 mm wide....
... Impacted Instrument Set offers maximum distraction with ... offered by the Tangent Posterior Impacted Instrument ... ability to reproduce the technique. Set offers ... vertebral body distraction. A variety of sizes ...
Medicine Products: