Navigation Links
The beat goes on: Modeling the human heart
Date:4/10/2013

tions for arrhythmia in order to predict a drug's pro- or anti-arrhythmic effects. But with heart models, that's possible.

Drug companies often test drugs at the cell level, which does not give as complete a picture as the whole-heart level, says Trayanova. Hence, Trayanova's team constructed a computational framework under which drug interactions with the whole heart can be studied. Their model focuses on the sodium channel, particularly sodium channel blockers, which are often used as drugs in arrhythmia treatments. The modeling of drug-channel interactions in order to determine the effects of drugs on electrical activity in the heart can help develop a drug-screening system for treatment applications.

Treatment of arrhythmias:

Trayanova's team also studies other methods to terminate arrhythmias using computational models.

Defibrillation

Atrial fibrillation or cardiac arrhythmia that occurs in the heart's upper chambersis a common form of arrhythmia. It is one of the most predominant diseases affecting our aging population. While it is not lethal, it is a major risk factor for stroke, and can be extremely unpleasant, says Trayanova.

A procedure that is often used by physicians to treat atrial fibrillation, called defibrillation, delivers an electric shock to the patient's heart, resetting it to a normal rhythm.

However, this process can be inconsistent. In some cases, the frequency or magnitude may be insufficient to block the arrhythmia, and the process fails. In addition, defibrillation that is currently used clinically is an extraordinarily painful process, says Trayanova. Hence, her lab has used models to come up with a new way to simultaneously defibrillate the heart while blocking nerve conduction in the nerves that carry pain, targeting them for pain suppression.

Cardiac Ablation

Another commonly-used procedure for terminating arrhythmias is cardiac a
'/>"/>

Contact: Karthika Muthukumaraswamy
karthika@siam.org
267-350-6383
Society for Industrial and Applied Mathematics
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. HHS enlists Archimedes Inc. to expand governments use of health care modeling
2. Modeling the demise of migrating brain tumor cells
3. Modeling sepsis in newborns
4. Modeling Good Research Practices guidelines for modeling in health care research available now
5. NLP Logix Signed to Provide Predictive Modeling Services for Worker Compensation Physical Therapy Provider
6. UK-Based Laminin Solutions and NLP Logix Formalize Agreement to Leverage the Power and Flexibility of M-Files with Big Data Predictive Modeling
7. Home Restoration Services of Minneapolis Receives Houzz’s 2013 ‘Best Of Remodeling’ Award
8. Recon 2 modeling may help tailor treatments for patients with metabolic diseases, cancer
9. New drug prevents spread of human prostate cancer cells
10. Scientists solving the mystery of human consciousness
11. First targeted nanomedicine to enter human clinical studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... HealthDay Reporter THURSDAY, Dec. 18, ... States -- along with Angelina Jolie,s chickenpox and the ... in the nation,s public health defense against infectious disease, ... Half of U.S. states are poorly prepared to ... was the main conclusion of the report issued jointly ...
(Date:12/19/2014)... Hands On Mobile Spa, has announced they now have a ... been transformed into a utopia for the Long Island community ... The Virtual Tour showcases the beauty of the Spa On ... more. , The Virtual Tour shows viewers each of the ... overhauled Winnebago. Marla Kaplan-Pelle, Director states " It's hard to ...
(Date:12/19/2014)... After a 13-year absence from active touring, the ... stage to entertain his many worldwide fans. Trisha Yearwood ... successful tour has been steadily expanding since the very ... Ticketability.com for a large inventory of Garth Brooks ... , Music fans have had a long wait for ...
(Date:12/19/2014)... new study suggests a possible link between certain menopause ... sweats -- and higher rates of hip fractures and ... affecting about 60 percent of women. The hormonal changes ... then face a higher risk of weakened bones and ... or severe menopausal symptoms are more likely to have ...
(Date:12/19/2014)... (HealthDay News) -- Prostaglandin analogue eye drops -- a ... risk of vision loss in patients with the eye ... by David Garway-Heath, of the Moorfields Eye Hospital and ... more than 500 people newly diagnosed with open-angle glaucoma ... one of the leading causes of blindness. About ...
Breaking Medicine News(10 mins):Health News:Most States Not Ready to Handle Infectious Disease Outbreaks: Report 2Health News:Most States Not Ready to Handle Infectious Disease Outbreaks: Report 3Health News:Most States Not Ready to Handle Infectious Disease Outbreaks: Report 4Health News:A Virtual Tour Of Hands On Mobile Massage Spa Is Now Available 2Health News:A Virtual Tour Of Hands On Mobile Massage Spa Is Now Available 3Health News:Garth Brooks Tickets for Joe Louis Arena: Ticketability.com Becomes a Popular Destination for Discount Tickets for Garth Brooks’ Detroit Concerts Set for February 27-28 2Health News:Severe Hot Flashes During Menopause May Raise Hip Fracture Risk Later: Study 2Health News:Study Supports Benefit of Widely Used Glaucoma Drug 2
... effective in differentiating the blood supply to medial and lateral ... according to a study conducted by researchers at the University ... in Petah Tikva, Israel. , Blood supply of medial ... tumors may be supplied by both the internal or lateral ...
... evaluating and diagnosing small bowel disorders is an effective ... to a recent study conducted by researchers at the ... India. Sonoenteroclysis is a new way of doing ... nasojejunal tube in order to alleviate gas in the ...
... PET/CT can help spare patients with clinically operable cervical ... not lead to increased survival of these patients, a ... to determine the value of pretreatment imaging in the ... MD, MPH, of Massachusetts General Hospital in Boston, and ...
... used to measure cardiac function and has the potential ... a preliminary study indicates. , CT coronary angiography provides ... however, CT coronary angiography uses a high radiation dose ... examinations, can evaluate structure and function with no or ...
... Although guidelines keep changing regarding screening mammography in elderly ... benefit from this exam, showing that with frequent mammograms ... recent study conducted by researchers at Jacobi Medical Center ... , Our initial interest was sparked by the ...
... how red blood cell production is controlled could lead ... anaemia, according to West Australian medical researchers. , The ... the journal of the American Society of Hematology and ... Australian scientists, led by Western Australian Institute for Medical ...
Cached Medicine News:Health News:New procedure in diagnosing small bowel disorders proves efficient and effective 2Health News:Screening mammography in elderly patients beneficial 2Health News:Twin findings raise hopes of improved anemia treatments 2
(Date:12/19/2014)... 18, 2014 Capnia, Inc. (NASDAQ: ... medical diagnostics based on its proprietary Sensalyze™ Technology ... announced financial results for the third quarter and ... "Following the completion of our initial public offering ... the recently initiated CoSense® commercial launch," said Anish ...
(Date:12/19/2014)... Dec. 18, 2014   Aratana Therapeutics, Inc ... company focused on the licensing, development and commercialization ... positive results from its pivotal field study of ... pain in dogs with osteoarthritis.  In the study, ... scores that were statistically significant compared to placebo ...
(Date:12/17/2014)... Alemania, December 17, 2014 Los ... con un alto nivel de gasto en investigación y ... 2013/14 (finalizado el 30 de septiembre de 2014) ZEISS ... 4.287 millones de euros (año anterior: 4.190 millones de ... desfavorables. Las ganancias (EBIT) crecieron un 14 por ciento, ...
Breaking Medicine Technology:Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 4Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 5ZEISS confirma su posición en un entorno difícil 2
... 22, 2012  Argon Medical Devices, Inc. announced today ... catheter, licensed from Rex Medical, LP, designed to ... treatments. "UltraStream provides clinicians with an ... life for their patients," commented George Leondis, President ...
...  Dune Medical Devices, the manufacturer of the MarginProbe ® ... experts in the field of breast cancer regarding the ... the importance of margin assessment in breast conserving surgery. ... with the MarginProbe System, designed to improve a surgeon,s ...
Cached Medicine Technology:Argon Medical Devices Announces The Launch of a Unique New Chronic Hemodialysis Catheter 2Dune Medical Devices Hosts Symposium Featuring MarginProbe® System at European Breast Cancer Conference 2Dune Medical Devices Hosts Symposium Featuring MarginProbe® System at European Breast Cancer Conference 3
... The QC Manager Point-of-Care Data Management System ... Blood Glucose Testing System and the Precision ... simple, automated way to collect, analyze, and ... format. It provides an essential laboratory tool ...
... The CELL-DYN SMS consistently produces high-quality blood ... consistent blood films every time, eliminating the ... significantly high or low hematocrit values. In ... mixes, identifies the sample, and aspirates only ...
... The QuickVue In-Line Strep A Test allows for ... directly from patient throat swab specimens. , ,QuickVue ... and is the first strep A test waived ... rapid procedure allow testing to take place at ...
... The IntraLase FS laser introduces new ... Surgeons now have the opportunity to ... alternative to a microkeratome for creating the ... IntraLase FS laser and proprietary IntraLASIK software, ...
Medicine Products: