Navigation Links
The Texas Institute of Dermatology Team Finds Easy-to-Apply, Topical Drug Just as Good as Injectable Compound for a Disfigurating Skin Infection
Date:3/5/2009

SAN ANTONIO, March 5 /PRNewswire/ -- A plentiful, inexpensive, topical compound is as effective at treating the skin lesions of Middle Eastern and African leishmaniasis as is the standard therapy, a less-available, costlier compound injected into lesions. That's one of the findings of a research team from Johns Hopkins University, Harvard University, Thomas Jefferson University and led by Reza F. Ghohestani, M.D., Ph.D., director of the Texas Institute of Dermatology and an associate professor of medicine at The University of Texas Health Science Center at San Antonio.

The panel, reporting in the prestigious peer-reviewed journal Public Library of Science Neglected Tropical Diseases, analyzed 14 major clinical research trials that enrolled 1,221 patients. The trials compared the standard therapeutics, known as pentavalent antimony compounds, with the topical treatment, paramomycin. Old World leishmaniasis infection is caused by parasites carried by the desert sandfly and can be found mainly in the Middle East, Mediterranean Sea coastal areas, Africa, and Asia.

More than 12 million people in 88 countries suffer from leishmaniasis and 2 million new cases are diagnosed annually, the authors wrote.

"Millions of people worldwide suffer with leishmaniasis, but we in South Texas should keep in mind that cutaneous leishmaniasis is not a rare entity here, either," Dr. Ghohestani said. "In our area the infection is mainly seen in people coming from Mexico and soldiers returning from Iraq."

Pentavalent antimony compounds were considered the main therapeutic option for all types of cutaneous leishmaniasis for decades. They were given intravenously, into muscle or into lesions.

"Our findings suggest that the topical paramomycin can be a good alternative for the Old World type of leishmaniasis, especially if MBCL is added," Dr. Ghohestani said. "Our group is now focused on improving delivery of paramomycin to the skin." The team is working with the Eastern Mediterranean regional office of the World Health Organization on this project.

The Texas Institute of Dermatology is the sole dermatology program in South Texas that combines basic and clinic research with clinical care. The Institute offers excellence in clinical dermatology as well as in basic and clinical research. General dermatology services are available for Skin Disorders. For more information, visit www.txdi.org or call 1-888-884-5557 Ext 2.

CONTACT: Maria E. Guerra of Texas Institute of Dermatology, 1-888-884-5557, Ext. 2, TexasDermatologyInstitute@gmail.com


'/>"/>
SOURCE Texas Institute of Dermatology
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Austin, Texas, Physicians Second in Nation to Perform New Procedure for Difficult-to-Treat Atrial Fibrillation Cases
2. Texas Cardiac Arrhythmia Institute at St. Davids Medical Center First in Nation to Use NaviStar(R) RMT ThermoCool(R) Catheter Since Technology Received FDA Approval
3. Motor behavioral research at UH moves to prestigious Texas Medical Center
4. New Texas Study Reveals Serious Flaws in Abstinence Programs
5. Texas Association of Health Underwriters Announces 15th Annual Day at the Capitol
6. Partnership for Prescription Assistance Prepared to Help Texas Workers Hurt by Recession
7. University of Texas engineers receive $3.2 million in National Science Foundation CAREER awards
8. Accordent Delivers Medical Lecture Capture Platform for University of Texas Health Sciences Center
9. Texas Mutual Wins National Employee Wellness Award
10. New Research Study in Houston, Texas Seeks Improved Quality of Life for People in the Future with Schizophrenia
11. Texas Health Dallas New Intensivist Program Puts Critical-Care Specialists in the ICU - All the Time
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/6/2016)... , ... February 06, 2016 , ... With the ... add warm color grades to their footage. A LUT is a Lookup Table that ... to the corresponding color indicated by the table. By manipulating each pixel, LUT's can ...
(Date:2/5/2016)... ... ... Steven Tonkinson, 36, of Coconut Grove, Florida, ran the Miami Marathon on ... This year, he ran all 26.2 miles with a green 25-pound ShelterBox strapped to ... , This Sunday, while many are watching the Superbowl, Steven Tonkinson will strap on ...
(Date:2/5/2016)... & Salt Lake City, UT (PRWEB) , ... February 05, 2016 ... ... of Activz Whole-Food Nutrition , announced that the much-anticipated feature with author Jahnavi ... New Really Cool Humans Amateur TV Network. , Each week, on his weekly Whole-Food ...
(Date:2/5/2016)... FL (PRWEB) , ... February 05, 2016 , ... ... the largest domestic franchisees of Popeyes Louisiana Kitchen restaurants, launched the 14th annual ... awareness for kids and adults with muscular dystrophy, ALS and related diseases that ...
(Date:2/5/2016)... ... February 05, 2016 , ... Freed-Hardeman University President Joe A. ... a joint enrollment and degree completion agreement. The agreement, which begins with ... at FHU|Dickson. , The agreement allows students to be jointly admitted to ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... Feb. 5, 2016  Redwood Scientific Technologies, Inc. announced ... designed to help women balance their hormones. This product ... Jason Cardiff , President and CEO. ... to help the millions of women across the country ... of imbalanced hormones. Our research and development team is ...
(Date:2/5/2016)... 5, 2016  Patients in Alabama ... (HIFU) therapy no longer have to travel out of state. ... with Urology Centers of Alabama to provide a ... for qualifying patients. Alabama ... treatment of prostate cancer using many different modalities. They are ...
(Date:2/5/2016)... Feb. 5, 2016  Venice,s newest laser clinic, ... first of its kind in the area and ... advanced laser treatment. The physician-owned and operated laser ... Suncoast by storm with its revitalizing skin care ... multi-wavelength Astanza Trinity technology. http://photos.prnewswire.com/prnh/20160204/329957 ...
Breaking Medicine Technology: