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The Surgeons of Los Angeles Colon and Rectal Surgical Associates are Now Offering Exparel for Use in Local Anesthesia During Anorectal Operations
Date:5/14/2013

if you will, which contain the anesthetic bupivicaine, which is delivered to the precise location where it is needed. It then diffuses slowly into the tissues, over 72 hours, and provides extended post-operative relief.”

About Exparel®, A New Type of Delivery System

Exparel® is a local anesthetic and delivery system injected into the affected area at the beginning of a medical operation. The anesthetic drug bupivicaine is used in conjunction with the delivery system known as DepoFoam®, and has been clinically proven to be safe and effective. The bupivicaine is surrounded by DepoFoam® in the form of microvesicles, and the use of Exparel® in this manner has been shown to reduce the need for opioid pain medications post-operatively. The anesthetic may be effective for up to 72 hours after injection.

The difference between microsomal bupvicaine and other types of local anesthetic injections is the manner in which it is delivered. While injections are used for the majority of local anesthestic drugs, the vesicles that contain the medication provide a slow release that leads to prolonged pain relief. Exparel® has been shown to be most effective when injected directly into the site of the operation, and often leads to an increase in the length of time before opioid pain relief is needed. Studies have shown the median time before opioids are used with normal local anesthesia is 1.2 hours. With Exparel®, this time increases to almost 15 hours, thus reducing the risks associated with opioid use. Additionally, administering Exparel® has reduced the amount of supplemental oral pain medication.

About Los Angeles Colon and Rectal Surgical Associates
Los Angeles Colon and Rectal Surgical Associates was formed in 1957, and provides patients with focused diagnostic, compassionate medical and surgical treatment. The doctors specialize in the diagnosis and treatment of various diseases that affect the c
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