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The Oncologist Pays Tribute to Dr. Judah Folkman
Date:2/27/2008

Pioneering Discoveries Led to Angiogenesis-Inhibiting Drugs for Cancer

Treatment

DURHAM, N.C., Feb. 27 /PRNewswire/ -- The February issue of The Oncologist presents a special tribute to the late Judah Folkman, M.D. -- a legendary surgeon and researcher whose scientific insight led to the development of an entirely new class of drugs for the treatment of cancers.

Dr. Folkman was best known for his work in discovering the importance of new blood vessel formation -- a process called angiogenesis -- for the growth of cancers. His discoveries led to the development of medications called angiogenesis inhibitors, which today are among the most promising new cancer treatments. At the time of his death in January, Dr. Folkman was the Julia Dyckman Andrus Professor of Pediatric Surgery and professor of cell biology at Harvard Medical School, and Director of the Vascular Biology Program at Children's Hospital Boston.

In this month's special tribute, leading scientists and physicians share recollections honoring Dr. Folkman's scientific vision, energy, and compassion. Their essays highlight Dr. Folkman's determination in his twenty- year fight against disbelief in the possibilities of anti-angiogenesis treatment for cancer. "He was patient and persevered on the road to his goal, never neglecting the rules of good science," writes Dr. H.M. Pinedo of VUmc Cancer Center, Amsterdam.

Today, more than one million patients have received some form of angiogenesis inhibitor therapy, estimates Dr. Bruce Chabner of Harvard Medical School and Massachusetts General Hospital, and Editor-in-Chief of "The Oncologist." In addition, over a thousand laboratories are working to explore the concept further. Future research will help to clarify the best uses of angiogenesis inhibitor therapy, and to develop new medications that are more effective and safer -- and perhaps one day, useful in preventing cancers in patients at high ris
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SOURCE AlphaMed Press
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