Navigation Links
The ORIGIN-GRACE study
Date:8/27/2012

Munich, Germany A sub-study of the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial, designed to investigate the effect of insulin glargine and omega-3 fatty acids on atherosclerosis progression, has found that, compared to standard care, only insulin glargine (a long-acting insulin) had a "modest" statistically non-significant reducing effect on the primary outcome of rate of change in maximum carotid intima media thickness (CIMT) at 12 carotid sites.

However, while insulin glargine did significantly reduce the secondary outcomes of the study (the annualised rates of change in maximum CIMT for the common carotid artery and for the common carotid plus bifurcation sites), there was no differences in either the primary or secondary outcomes between the omega-3 polyunsaturated fatty acid supplements and placebo groups.

"Our study demonstrates that in high-risk people with established cardiovascular disease or with cardiovascular risk factors plus type 2 diabetes or pre-diabetes, insulin glargine modestly retards the progression of atherosclerosis," said first investigator Professor Eva Lonn, Professor of Medicine and Population Health Research Scientist at McMaster University, Hamilton, Ontario, Canada.

As background to the trial, known as the Glucose Reduction and Atherosclerosis Continuing Evaluation Study (GRACE) study, Professor Lonn explained that the effects of treatment with insulin titrated to normalise fasting plasma glucose levels and with omega-3 polyunsaturated fatty acid supplements (fish oil supplements) on atherosclerosis progression in people with type 2 diabetes or pre-diabetes are unknown.

The GRACE study assessed the effects of insulin glargine and omega-3 fatty acids by performing yearly high-resolution carotid ultrasound examinations for five years and detailed precise measurements of CIMT. Patients were recruited from 32 centers in seven countries. At baseline patients' mean age was
'/>"/>

Contact: ESC Press Office
press@escardio.org
European Society of Cardiology
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. People of normal weight with belly fat at highest death risk, Mayo Clinic study
2. New Blood Thinner Effient No Better Than Plavix at Preventing Heart Trouble: Study
3. Study examines factors associated with improvement in survival from heart attack in France
4. Study: Clot removal devices successful tools for acute ischemic stroke treatment
5. Global study suggests need for strategies to combat unhealthy lifestyles among the poor and the rich
6. Multiple Brain Tumors Even More Malignant: Study
7. Meditation May Help Fight Loneliness, Study Says
8. Spirituality May Boost Mental Health: Study
9. Study identifies human melanoma stem cells
10. Study helps pancreatic cancer patients make hard choices
11. Anorexics Cant Judge Own Body Size: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... Benefit Express Services, LLC, a leader in ... will be hosting a free Workplace Wellness webinar on ... The presentation will focus on making sure your workplace ... Health Care Reform Requirements. The team will also share ... Express regularly hosts free educational webinars on issues that ...
(Date:5/21/2013)... Three major Ohio universities and four hospitals have ... a new collaborative research program aimed exclusively at finding ... Dimes intends to invest $10 million in the program ... Prematurity Research Center -- Ohio Collaborative is a unique ... the March of Dimes. "This new transdisciplinary, team-based research ...
(Date:5/21/2013)... 2013 EMBO announced today that 52 outstanding researchers ... membership. Forty-three of the researchers reside in Europe and ... nine Associate Members from Canada, China, India, Japan and ... 1600 life scientists. , "Our members are the basis ... Maria Leptin said. "We have been building our network ...
(Date:5/21/2013)... Healthcare Solutions, the parent company ... announced that it was honored to receive the ... Conferred annually, the Innovation Award recognizes a ... cutting edge programs that improves cost and/or quality ... for its clinical and IT solutions that have ...
(Date:5/21/2013)... Two-thirds of patients who have been diagnosed ... that they engage in at least one type of ... findings from the National Health and Wellness Survey ... research will be presented today at the 18th Annual ... Outcomes Research) in New Orleans. , “Cancer ...
Breaking Medicine News(10 mins):Health News:Benefit Express to Host Workplace Wellness Webinar 2Health News:New multi-million dollar research center aims to solve the mystery of premature birth 2Health News:New multi-million dollar research center aims to solve the mystery of premature birth 3Health News:EMBO announces 52 new members for 2013 2Health News:Healthcare Solutions Receives Innovation Award From Catamaran 2Health News:Two in Three Cancer Patients are Non-Adherent with Their Medications, According to Kantar Health Research 2Health News:Two in Three Cancer Patients are Non-Adherent with Their Medications, According to Kantar Health Research 3
... By Jenifer Goodwin HealthDay Reporter , MONDAY, Sept. ... more likely to suffer socially and emotionally than their normal-weight ... in Australia checked children,s BMI, a measure of height and ... few years later. Parents and teachers filled out questionnaires that ...
... , MONDAY, Sept. 19 (HealthDay News) -- More than ... attack are delayed in getting the emergency artery-opening intervention ... from the fact that only a quarter of American ... that many patients who experience a so-called "ST-segment elevation ...
... D.C. Psychosocial stress could play a role in ... populations, according to study results presented at the Fourth ... held here from Sept. 18-21, 2011. "We found ... reported higher levels of stress than whites, and that ...
... COLUMBIA, Mo. For medications to be effective, they must ... time, as prescribed by healthcare providers. The World Health ... incorrectly, costing the U.S. health care system and consumers ... University of Missouri researchers say medication non-adherence interventions should ...
... effects of cancer treatments. Beth Faiman MSN, ... School of Nursing at Case Western Reserve University, is ... effects for people with blood and bone marrow cancers. ... 1994 at the Cleveland Clinic Taussig Cancer Center with ...
... , MONDAY, Sept. 19 (HealthDay News) -- American youngsters ... than their northern neighbors due to a public health policy ... 4-year olds, according to a Canadian-American research team. The ... the U.S. Advisory Committee on Immunization Practices in 2006. To ...
Cached Medicine News:Health News:Obese Kids May Face Social, Emotional Woes 2Health News:Obese Kids May Face Social, Emotional Woes 3Health News:One-Third of Severe Heart Attack Patients Have Treatment Delays 2Health News:Integrating medication regimens into daily routines can improve adherence 2Health News:CWRU research examines over-the-counter drug's effect on chemo's side effects 2Health News:U.S. Flu Shot Policy Shields More Kids Than Canada's Program, Study Finds 2
(Date:5/21/2013)... /PRNewswire-iReach/ -- The 2013 Pharma ChemOutsourcing Show slated for ... number of "Emerging" small molecule biotech company chemists ... .  "No one saw this coming", commented ... still 4 months away and we may end up ... surprise and great news for attendees". Thecurrent list of ...
(Date:5/21/2013)... 21, 2013  IsoRay, Inc. (AMEX: ISR ... entered into an exclusive international distribution agreement with IASIS ... in Greece . IsoRay is a ... medical radioisotope applications for brain cancer, lung cancer, head ... IASIS Medical is ideally suited to ...
(Date:5/21/2013)...  The North Shore-LIJ Health System is expanding a ... at North Shore University Hospital in Manhasset, ... at Forest Hills (NY) Hospital. ... new pilot program strengthens patient safety by providing hospitals ... first time in the US that remote video auditing ...
Breaking Medicine Technology:Emerging Pharma at ChemOutsourcing 2013 in Record Numbers for Upcoming September Show 2IsoRay Announces A New International Distributor For Greece 2IsoRay Announces A New International Distributor For Greece 3North Shore-LIJ Extends Use of 3rd Party Remote Video Auditing into ORs 2North Shore-LIJ Extends Use of 3rd Party Remote Video Auditing into ORs 3North Shore-LIJ Extends Use of 3rd Party Remote Video Auditing into ORs 4
... Tango exercise BP monitor is designed to ... and diastolic BP along with heart rate. ... for use in treadmill, ergometer and pharmacological ... for use in research environments., ,Tango ...
...
...
... Tamp is an orthopedic balloon designed to ... Like an angioplasty balloon, it can be ... is inflated with radiopaque contrast medium. The ... volume. The force of balloon growth compacts ...
Medicine Products: