Navigation Links
The Montreal Children's Hospital of the MUHC begins search for causes of autism

This release is available in French.

Montreal, 7 May 2008 Dr. Eric Fombonne, from the Research Institute of the MUHC at the Montreal Childrens Hospital, is involved in a multi-site consortium to gather DNA samples from 2,000 autism patients and their families over the next three years.

The Simons Simplex Collection (SSC) is a coordinated effort to create a database of genetic and behavioral information about cases where there is only one family member with autism. This group, which represents the great majority of autism spectrum disorders, Is expected to lead to the discovery of new genetic factors that increase the risk of autism.

In addition, this database will be accessible online by the scientific community and will represent an invaluable tool for future research projects.

This database will link state-of-the-art genetic analysis to very detailed behavioral assessments. This is an unprecedented project that could greatly enhance our understanding of underlying biological processes, explains Dr. Fombonne. This is an important step towards the unraveling of genetic mechanisms and understanding the pathophysiology of this disorder of brain development.

Families are currently being recruited to participate in an initial assessment and then may be invited to participate in other research projects as work continues. Those eligible to participate are families with only one child with an autism spectrum disorder (ASD) who is four years of age or older; with one or more siblings without an ASD, age four or older; and biological parents without an ASD and who are willing to participate. Eligible children with an ASD will receive a behavioral assessment and all family members will donate blood, a source of DNA. A small number of families with no siblings or siblings under the age of four may be eligible to participate in the study.

The MUHC is committed to recruiting 200 families by the end of 2009. This represents an important challenge, but being the only centre in Canada we hope to be able to attract the required number of English speaking patients, says Dr. Fombonne.

In addition to the Research Institute of the MUHC, the SSC will be conducted at Baylor University, Columbia University, Emory University, Harvard University, the University of California, Los Angeles (UCLA), the University of Illinois-Chicago, the University of Michigan, the University of Missouri, the University of Washington, Vanderbilt University, Washington University, and Yale University.


Contact: Isabelle Kling
McGill University Health Centre

Related medicine news :

1. Worrell Inc. Acquires Gad Shaanan Design Operations in Montreal and San Diego
2. World fertility experts to meet in Montreal - IVF and IVM patients to provide first-person accounts at 14th World Congress
3. Siegel+Gale Designs New HOPE Portal for Childrens Hospital Los Angeles
4. Childrens Hospital Los Angeles Turns Off the Tap With Green Earth Waterless Carwash
5. Nautica Malibu Triathlon Presented by Toyota Raises $718,000 for Childrens Hospital Los Angeles Pediatric Cancer Research
6. Hospitals in Louisiana and Mississippi to Receive More Katrina Recovery Grants
7. Brooks Brothers CEO at St. Jude Childrens Research Hospital(R) To Announce Partnership With Stanford St. Jude Championship
8. Graduation Gift Books to Benefit Levine Childrens Hospital
9. Clarient Partners With Joint Venture Hospital Laboratories to Offer Pathologists Wide Array of Cancer Assays
10. Kaiser Foundation Health Plan and Hospitals Reports First Quarter 2008 Financial Results
11. Customer Communications Group Selected by The Childrens Hospital for Direct Marketing Expertise
Post Your Comments:
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort to ... treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain management ... (SCD) is a disorder of the red blood cells, which can cause episodes of ...
(Date:6/24/2016)... ... 2016 , ... The Pulmonary Hypertension Association (PHA) learned during ... two significant new grants to support its work to advance research and patient ... recognizing patients, medical professionals and scientists for their work in fighting pulmonary hypertension ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway ... call for a minimum wage raise to $12 an hour by 2020 and then adjusting ... restore the lost value of the minimum wage, assure the wage floor does not erode ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. ... articles published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... FRANCISCO, Calif. , June 24, 2016 /PRNewswire/ ... ), a biopharmaceutical company developing novel therapeutics for ... unmet needs, today announced the closing of its ... of common stock, at the public offering price ... in the offering were offered by GBT. GBT ...
(Date:6/24/2016)... Research and Markets has ... 2015-2025: Applications, Technologies, Forecasts" report to their ... Electronics, Smart Skin, Structural Health Monitoring, Composite Smart ... electronics involves electronic and/or electrical components and circuits ... structures such as vehicle bodies or conformally placed ...
(Date:6/24/2016)... , June 24, 2016  American Respiratory Labs (ARL), a ... now able to perform sophisticated lung assessments in patients, homes, thanks ... Inc. Patients are no longer limited to having ... PRO ® , ARL patients like Jeanne R. of ... the comfort of her own home. ...
Breaking Medicine Technology: