Navigation Links
The Melanoma Research Alliance Foundation supports CNIO research
Date:4/23/2013

A consortium led by the Spanish National Cancer Research Centre's researcher Mara S. Soengas −Programme Director of the Centres Molecular Pathology Programme and Leader of the CNIO Melanoma Group− has been selected to receive funding from the Melanoma Research Alliance (MRA), the most important private international melanoma research foundation, in order to advance research in melanoma; this type of skin tumour represents one of oncology's biggest challenges due to its high incidence and malignancy.

The main goals of the project, which has been awarded $900,000, are aimed at generating molecular tools and validating new compounds that block the formation of lymphatic vessels, one of the main routes that cancer cells use to conquer new organs and generate metastasis.

To this end, Soengas will coordinate the work of world-leading researchers in the fields of oncology, pathology, dermatology, medical chemistry or tumour spectrometry, from institutions such as the Swiss Federal Institute of Technology in Munich, the National Institute of Health and Medical Research in Paris, Ludwig Maximilian University in Munich or the Weill Cornell Medical College in New York.

According to Soengas, for decades, the prognosis for patients with melanoma has been largely defined by the presence or absence of tumour cells in the lymph nodes adjacent to the tumour. "Up until now, however, we have not been able to detect the activation of the lymphatic vessels (lymphangiogenesis) before melanoma cells disseminate through the organism", she adds.

This project seeks to provide a solution to this problem, in addition to validating efficient anti-metastatic drugs. "We have generated the first melanoma models to visualise the activation of lymphangiogenesis in vivo. These models will also allow us to carry out pharmacological studies to determine the efficiency and stability of new anti-metastatic therapies", says CNIO researcher.

Furthermore, researchers will study several drugs under clinical development, as well as nanoparticles discovered by CNIO that have led to the creation of Bioncotech Therapeutics, a CNIO spin-off dedicated to anti-cancer therapies.

With the current round of funding of $9.6 million, this award brings the total awarded by MRA in its 6-year history to almost $48 million, destined to promoting multidisciplinary research to improve the treatment of patients with melanoma.


'/>"/>

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)
Source:Eurekalert

Related medicine news :

1. Surgery Rates Rising for Non-Melanoma Skin Cancer: Study
2. Moffitt Cancer Center researchers working at frontiers of melanoma research
3. Women More Likely to Survive Melanoma Than Men: Study
4. Scientists Map Melanomas Genome
5. Two-Drug Combo May Be Safe for Melanoma Treatment
6. Melanoma a Big Threat to Older Men
7. Fish shed light on human melanoma
8. LA BioMed investigators, Drs. Kevin Bruhn and Noah Craft, develop novel treatment for melanoma
9. New Melanoma Drug May Extend Survival
10. New Guidelines Issued for Biopsy Use in Melanoma Patients
11. Melanoma-promoting gene discovered
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... temporary closing of Bruton Memorial Library on June 21 due to a possible lice infestation, ... aspect of head lice: the parasite’s ability to live away from a human host, and ... necessary one in the event that lice have simply gotten out of control. , As ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... ... ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for ... $12 an hour by 2020 and then adjusting it yearly to increase at the same ... wage, assure the wage floor does not erode again, and make future increases more predictable. ...
(Date:6/24/2016)... ... 2016 , ... Strategic Capital Partners, LLC (SCP) in concert ... capital for emerging technology companies. SCP has delivered investment events and professional ... than a million dollars of capital investment for five companies. The ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016 /PRNewswire/ ... pulmonary function testing company, is now able to perform sophisticated lung ... ndd Medical Technologies , Inc. Patients are ... labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients like ... any needed testing done in the comfort of her own home. ...
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/23/2016)... June 23, 2016  MedSource announced today that ... e-clinical software solution of choice.  This latest decision ... value to their clients by offering a state-of-the-art ... relationship establishes nowEDC as the EDC platform of ... full-service clients.  "nowEDC has long been a preferred ...
Breaking Medicine Technology: