Navigation Links
The Lancet Diabetes & Endocrinology: Large clinical trials to evaluate risks of testosterone treatment urgently needed
Date:4/27/2014

Physicians do not have sufficient information from clinical trials to understand the risks associated with the prescription of testosterone in older men, according to a Comment in The Lancet Diabetes & Endocrinology, written by Professor Stephanie Page, of the University of Washington and Harborview Medical Center, Seattle, USA.

While the benefits of testosterone therapy in younger men with a deficiency of the hormone are well established, testosterone is now widely prescribed to older men, particularly in the USA.

Existing studies have produced conflicting findings over whether the prescription of testosterone is associated with increased cardiovascular risk in older men, and ongoing studies are unlikely to adequately address this question, meaning that even if an appropriately powered trial were to start today, reliable safety data are at least a decade away.

According to Professor Page, "In an era when millions of men are using testosterone every day, support is urgently needed from both the public and medical communities to fund an appropriate clinical study to assess the risks and benefits of testosterone treatment in older men. There is a danger that funding and regulatory agencies will overinterpret the evidence from existing and ongoing observational studies, and conclude that larger and longer clinical trials are unnecessary and unwarranted. This conclusion would do men's health a disservice."*

"Testosterone is a billion dollar industry, probably fuelled partly by direct to consumer advertising and some degree of overprescription," Professor Page adds. "Physicians need to discuss with their patients that we simply do not fully understand the risks associated with testosterone use in older men, and use conservative treatment guidelines such as those provided by the Endocrine Society to guide therapeutic decisions."*


'/>"/>

Contact: Stephanie Page
page@u.washington.edu
The Lancet
Source:Eurekalert

Page: 1

Related medicine news :

1. Premier global health journal, The Lancet, releases series on universal health coverage
2. Indias patent laws under pressure: The Lancet special report
3. Lancet Oncology: Long-term side-effects of targeted therapies in pediatric cancer patients
4. 1-year results of ADAPT-DES trial published in The Lancet
5. More Babies are Oversized as Maternal Obesity Rate Rises, Lancet Report Says
6. The Lancet: China halves tuberculosis prevalence in just 20 years
7. The Lancet journals: World TB Day media alert
8. How a cancer drug leads to diabetes
9. Heart failure patients with diabetes may benefit from higher glucose levels
10. Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study
11. Mouse Study Hints at New Path for Diabetes Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... ... Chocolate Biscuit”: a biographical account following a man who went on to support his country ... Ivey, born in Lynn Haven, Florida and at the age of 5, his family moved ... he joined the Navy and got married right out of boot camp. , He ...
(Date:1/20/2017)... ... , ... “Christmas in Suffolk”: a story of love, secrets, and mystery. ... Lafayette, Indiana where she works in a daycare and looks for inspiration in the ... Christian Faith Publishing, Sara Seymour’s new book is an adventure of love and secrets. ...
(Date:1/20/2017)... ... ... Land of More and More”: a brilliant story for children and adults alike ... achievable answer. “The Land of More and More” is the creation of published author, ... where he works with the children’s ministry department. , Michael says that he ...
(Date:1/19/2017)... ... January 19, 2017 , ... ... Aerolib Learning Management System: an On-demand E-learning system for Clinical and Regulatory ... Administration that is based on Aerolib`s successful education methodology of Disease Specific ...
(Date:1/19/2017)... ... January 19, 2017 , ... With the cold weather here, many people will have to ... efficient when clearing large amounts of snow, but they can be dangerous when used incorrectly. ... Product Safety Commission for the proper use of snow blowers:, , ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... 2017 Avillion LLP, a co-developer and financier ... Weinberg , MD MBA as Chief Medical Officer. Dr Weinberg will ... . ... Weinberg has spent more than 17 years as a pharmaceutical and ... micro-cap biotech. Over the course of his career, he has interfaced ...
(Date:1/19/2017)... , Jan. 19, 2017 Report Details ... Devices Market? Which areas are going to grow at ... revenues to 2026, assessing data, trends, opportunities and prospects. ... graphs. Discover the most lucrative areas in the industry ... you assess forecasted sales across the all the major ...
(Date:1/19/2017)... -- Conference Call and Webcast to Follow Vanda Pharmaceuticals ... release results for the fourth quarter of 2016 on Wednesday, February ... ... 4:30 PM ET on Wednesday, February 15, 2017, during which management ... and other corporate activities. To participate in the conference call, please ...
Breaking Medicine Technology: