Navigation Links
The Lancet Diabetes & Endocrinology: Large clinical trials to evaluate risks of testosterone treatment urgently needed
Date:4/27/2014

Physicians do not have sufficient information from clinical trials to understand the risks associated with the prescription of testosterone in older men, according to a Comment in The Lancet Diabetes & Endocrinology, written by Professor Stephanie Page, of the University of Washington and Harborview Medical Center, Seattle, USA.

While the benefits of testosterone therapy in younger men with a deficiency of the hormone are well established, testosterone is now widely prescribed to older men, particularly in the USA.

Existing studies have produced conflicting findings over whether the prescription of testosterone is associated with increased cardiovascular risk in older men, and ongoing studies are unlikely to adequately address this question, meaning that even if an appropriately powered trial were to start today, reliable safety data are at least a decade away.

According to Professor Page, "In an era when millions of men are using testosterone every day, support is urgently needed from both the public and medical communities to fund an appropriate clinical study to assess the risks and benefits of testosterone treatment in older men. There is a danger that funding and regulatory agencies will overinterpret the evidence from existing and ongoing observational studies, and conclude that larger and longer clinical trials are unnecessary and unwarranted. This conclusion would do men's health a disservice."*

"Testosterone is a billion dollar industry, probably fuelled partly by direct to consumer advertising and some degree of overprescription," Professor Page adds. "Physicians need to discuss with their patients that we simply do not fully understand the risks associated with testosterone use in older men, and use conservative treatment guidelines such as those provided by the Endocrine Society to guide therapeutic decisions."*


'/>"/>

Contact: Stephanie Page
page@u.washington.edu
The Lancet
Source:Eurekalert

Page: 1

Related medicine news :

1. Premier global health journal, The Lancet, releases series on universal health coverage
2. Indias patent laws under pressure: The Lancet special report
3. Lancet Oncology: Long-term side-effects of targeted therapies in pediatric cancer patients
4. 1-year results of ADAPT-DES trial published in The Lancet
5. More Babies are Oversized as Maternal Obesity Rate Rises, Lancet Report Says
6. The Lancet: China halves tuberculosis prevalence in just 20 years
7. The Lancet journals: World TB Day media alert
8. How a cancer drug leads to diabetes
9. Heart failure patients with diabetes may benefit from higher glucose levels
10. Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study
11. Mouse Study Hints at New Path for Diabetes Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2016)... , ... May 23, 2016 , ... ... Texas Veterinary Medical Association (TVMA) reminds pet owners that intervening at the first ... Heatstroke occurs when a pet’s normal body mechanisms cannot keep the body’s temperature ...
(Date:5/23/2016)... CA (PRWEB) , ... May 23, 2016 , ... ComplianceOnline, ... regulatory subjects will host medical device summit on September 15 and 16, 2016 ... leading experts and former FDA office bearers will be one of the largest gatherings ...
(Date:5/23/2016)... ... May 23, 2016 , ... The Society for Women’s Health Research (SWHR) announced ... from that role. , “No one in Washington led the way to advance women’s ... Florence Haseltine, MD, PhD. “We offer our deep gratitude to Phyllis for her passion ...
(Date:5/23/2016)... ... May 23, 2016 , ... During Logan University’s ... Process Inc. awarded $6,000 in chiropractic scholarships. The winners of the three ... in her fifth trimester of classes at Logan. , “Standard Process has been ...
(Date:5/23/2016)... IL (PRWEB) , ... May 23, 2016 , ... ... largest provider of distance education worldwide for people who are blind or visually ... the 10-year tenure of retiring President Charles E. Young. Hadley’s Board of Trustees ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... --Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today the start ... hands-on learning experience is a 12-week summer program, May ... and Internship programs bring participants to ... are provided optional housing free of charge through Diplomat ... Riverfront Residence Hall to foster communication and collaboration among ...
(Date:5/23/2016)... , May 23, 2016 ... Devices, Diagnostics and Monitoring, and Vision Care ... Which areas are going to grow at the fastest ... revenues to 2026, assessing data, trends, opportunities and prospects. ... charts, and graphs. Discover the most lucrative areas in ...
(Date:5/23/2016)... -- Experts from various countries ... role of technology in innovative healthcare ... International Conference of VPS-Penn Medicine opened in Abu ... Sheikh Nahyan bin Mubarak Al Nahyan, Minister of Culture and ... provide personalized medicine and tailor-made healthcare in disease treatment and ...
Breaking Medicine Technology: