Navigation Links
The Lancet: New trial suggests cheaper drugs for common heart attack procedure could improve outcomes and save health budgets millions
Date:7/4/2014

A new study published in The Lancet compares outcomes for two drugs used to prevent blood clot formation during emergency heart attack treatment. The study suggests that use of one of the drugs, heparin, could result in improved outcomes (such as a reduced rate of repeat heart attacks), compared to the other drug tested, bivalirudin, which is in widespread use in high-income countries, and is around 400 times more expensive than heparin.

The results of the HEAT-PPCI trial suggest that systematic use of heparin rather than bivalirudin after primary percutaneous coronary intervention (PPCI) the most commonly used treatment for heart attack, which unblocks the arteries carrying blood to the heart could save health services substantial sums of money, at the same time as potentially improving patient outcomes.

Patients who undergo PPCI usually receive a combination of antithrombotic drugs to prevent any further blood clots forming during the procedure and after it has been completed. The most commonly used antithrombotic drugs are unfractionated heparin and bivalirudin, and although several previous trials have compared the two drugs, the evidence is unclear as to which drug results in better outcomes.

The trial took place at the Liverpool Heart and Chest Hospital in the UK, where 1829 patients undergoing emergency angiography (an x-ray examination of the heart's arteries after a suspected heart attack) were recruited to the trial. More than four fifths of these patients then went on to receive PPCI; approximately half received heparin, and half received bivalirudin. Researchers then recorded how many patients in both groups experienced a major adverse cardiac event, such as death or another heart attack, within 28 days after surgery.

The results show that overall rates of major adverse cardiac events were significantly lower in the group who received heparin, although the rates of adverse events were low, as expected, in both groups
'/>"/>

Contact: Matthew Back
matthew.back@lhch.nhs.uk
44-015-160-01423
The Lancet
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. The Lancet: Midwifery matters more than ever
2. The Lancet: UK has one of the highest death rates for children in western Europe
3. The Lancet: China halves tuberculosis prevalence in just 20 years
4. First evidence for painless atrial fibrillation treatment
5. ASPIRE Phase III trial of vaginal ring to prevent HIV completes enrollment of 2,629 women
6. GW leads clinical trial to reduce epileptic seizures in people with temporal lobe epilepsy
7. First first patient enrolled in PROSPECT II clinical trial
8. New definition of kidney disease for clinical trials could lead to new treatments
9. Trial uncovers potential dangers of chemotherapy regimen for bladder cancer patients
10. UH part of $7.5M NIH clinical trial on nearsightedness in children
11. Experimental trial represents promising step toward universal antidote for snakebite
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... older adults on five continents found that nearly 1 ... simple test that measures how fast people walk and ... for pre-dementia were twice as likely as others to ... scientists at Albert Einstein College of Medicine ... was published online on July 16, 2014 in ...
(Date:7/25/2014)... (PRWEB) July 25, 2014 Hastings and ... offering discount attorney’s fees with regard to personal injury ... provide a wide range of legal services for those ... negligence of another individual or corporation. Free initial consultation ... the validity of a potential personal injury claim ...
(Date:7/25/2014)... 2014 As thousands of transvaginal mesh ... Bernstein Liebhard LLP notes that the Food & Drug ... advocacy group, Public Citizen, to order a global recall ... May 1, 2014, and released to the public last ... a ban on the marketing of all surgical mesh ...
(Date:7/25/2014)... FRIDAY, July 25, 2014 (HealthDay News) -- Babies seem ... suggests. By the time women are 34 weeks ... of their mother,s voice reciting a familiar nursery rhyme, ... predominant source of sensory stimulation in the developing fetus," ... University of Florida,s College of Nursing, said in a ...
(Date:7/25/2014)... vulnerable neurons and reduce motor deficits in a ... University School of Medicine have shown. , The ... Parkinson,s Disease . , The findings demonstrate that ... at sufficient levels and have beneficial effects when ... Previous studies of XPro1595 in animals tested more ...
Breaking Medicine News(10 mins):Health News:Slow walking speed and memory complaints can predict dementia 2Health News:Slow walking speed and memory complaints can predict dementia 3Health News:Slow walking speed and memory complaints can predict dementia 4Health News:Hastings and Hastings Announces Complimentary Consultation Services 2Health News:Hastings and Hastings Announces Complimentary Consultation Services 3Health News:Transvaginal Mesh Lawsuit News: FDA Rejects Petition Seeking Ban and Global Recall of All Transvaginal Mesh Products, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Lawsuit News: FDA Rejects Petition Seeking Ban and Global Recall of All Transvaginal Mesh Products, Bernstein Liebhard LLP Reports 3Health News:Transvaginal Mesh Lawsuit News: FDA Rejects Petition Seeking Ban and Global Recall of All Transvaginal Mesh Products, Bernstein Liebhard LLP Reports 4Health News:Rhymes Reveal Evidence of Learning in the Womb 2Health News:Anti-inflammatory drug can prevent neuron loss in Parkinson's model 2
... Children exposed to chlorpyrifos-an insecticide, while in their mother’s ... by three years of age and also have a// ... in a peer-reviewed study conducted by Academy of Pediatrics. ... use in 2001, is still widely applied to agricultural ...
... Britain's heart experts are hoping to exploit the passion for ... people from the community not to delay calling// emergency help ... Asians in Britain have a 40-50 per cent higher death ... Asians are known to be reluctant to seek emergency help ...
... Meet organized by the city board of health on 5th ... use of Trans fat in the commercially prepared foods such ... Frieden, the health commissioner said, 'We hope that the board ... into consideration the concerns raised by 24,000 restaurateurs in New ...
... about chicken, which finds itself in the news, for all ... be hounded incessantly by germs. ,When Consumer reports ... 83% of the chickens were infected with either the campylobacter ... trigger diarrhea, cramping, nausea, fever, and vomiting, and can be ...
... A new study finds that the anti-craving drug, Naltrexone ... women who are trying to quit smoking appear //to ... individualized medicine, scientists are focusing on gender differences in ... Andrea King and her colleagues of the University of ...
... gained new ground to prove that your moms' advice, to eat ... best for you! If you chew your food well and take ... feeling better, says a new study. , Kathleen ... of this study. She compared the intake of calories of two ...
Cached Medicine News:Health News:Chlorpyrifos Affects Mental Development of Foetus 2Health News:British Heart Experts Use Cricket To Target South Asians 2
(Date:7/25/2014)... July 25, 2014 GrowBLOX Sciences, Inc. (OTCQB: GBLX) ... of Understanding ("MOU") with LaurelCo, LLC, an Illinois ... of both cultivation and dispensary medical marijuana licenses in the ... MOU, GBLX will acquire a 20% equity interest in LaurelCo, ... TM growing chambers, as well as all technology related ...
(Date:7/25/2014)... HOUSTON , July 25, 2014  Solanbridge Group ... has acquired the majority interest in Buzznbrewz.com and the ... been replaced with a fully executed Purchase Agreement. ... Solanbridge, stated "We are proud to have Mr. ... has decades of experience in the private sector and ...
(Date:7/25/2014)... -- IDEXX Laboratories, Inc. (NASDAQ: IDXX ) today ... increased 11% versus the prior year period to $390 ... quarter of 2014 versus the prior year period was ... 2 . Earnings per diluted share ("EPS") for the ... prior year period to $1.10."In the second quarter, we ...
Breaking Medicine Technology:GrowBLOX Sciences, Inc. Partners with LaurelCo, LLC to Obtain Licenses to Cultivate and Dispense Medical Marijuana in Illinois 2GrowBLOX Sciences, Inc. Partners with LaurelCo, LLC to Obtain Licenses to Cultivate and Dispense Medical Marijuana in Illinois 3Solanbridge Group Inc Announces Acquisition of Buzznbrewz.com 2IDEXX Laboratories Announces Second Quarter Results 2IDEXX Laboratories Announces Second Quarter Results 3IDEXX Laboratories Announces Second Quarter Results 4IDEXX Laboratories Announces Second Quarter Results 5IDEXX Laboratories Announces Second Quarter Results 6IDEXX Laboratories Announces Second Quarter Results 7IDEXX Laboratories Announces Second Quarter Results 8IDEXX Laboratories Announces Second Quarter Results 9IDEXX Laboratories Announces Second Quarter Results 10IDEXX Laboratories Announces Second Quarter Results 11IDEXX Laboratories Announces Second Quarter Results 12IDEXX Laboratories Announces Second Quarter Results 13IDEXX Laboratories Announces Second Quarter Results 14IDEXX Laboratories Announces Second Quarter Results 15IDEXX Laboratories Announces Second Quarter Results 16IDEXX Laboratories Announces Second Quarter Results 17IDEXX Laboratories Announces Second Quarter Results 18IDEXX Laboratories Announces Second Quarter Results 19IDEXX Laboratories Announces Second Quarter Results 20IDEXX Laboratories Announces Second Quarter Results 21IDEXX Laboratories Announces Second Quarter Results 22IDEXX Laboratories Announces Second Quarter Results 23IDEXX Laboratories Announces Second Quarter Results 24IDEXX Laboratories Announces Second Quarter Results 25IDEXX Laboratories Announces Second Quarter Results 26IDEXX Laboratories Announces Second Quarter Results 27IDEXX Laboratories Announces Second Quarter Results 28IDEXX Laboratories Announces Second Quarter Results 29IDEXX Laboratories Announces Second Quarter Results 30IDEXX Laboratories Announces Second Quarter Results 31IDEXX Laboratories Announces Second Quarter Results 32IDEXX Laboratories Announces Second Quarter Results 33
... Technology Applicable for the Detection of a Host of Amyloid Neurological ... ... Parkinson Disease, ROCKVILLE, Md., Aug. 29 Adlyfe, a ... announced today the publication of a study, "Detection of,misfolded prion protein ...
... 28 Gilbert Hospital is,the first hospital in ... in,extracorporeal shockwave lithotripsy in the fight against painful ... waves in a,non-invasive procedure to break down kidney ... System has been added to Gilbert,Hospital,s arsenal of ...
Cached Medicine Technology:Adlyfe Study on the Detection of Misfolded Proteins Published in the Journal Transfusion 2Adlyfe Study on the Detection of Misfolded Proteins Published in the Journal Transfusion 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: