Navigation Links
The Lancet: China halves tuberculosis prevalence in just 20 years
Date:3/17/2014

Over the last 20 years, China has more than halved its tuberculosis (TB) prevalence, with rates falling from 170 to 59 per 100 000 population. This unrivalled success has been driven by a massive scale-up of the directly observed, short-course (DOTS) strategy, from half the population in the 1990s to the entire country after 2000, according to findings from a 20-year-long analysis of national survey data, published in The Lancet.

"One of the key global TB targets set by the Stop TB Partnership aims to reduce tuberculosis prevalence by 50% between 1990 and 2015. This study in China is the first to show the feasibility of achieving such a target, and China achieved this 5 years earlier than the target date", says study leader Dr Yu Wang from the Chinese Center for Disease Control and Prevention in Beijing, China.

"Huge improvements in TB treatment, driven by a major shift in treatment from hospitals to local public health centres implementing the DOTS strategy, were largely responsible for this success."*

China is a major contributor to the TB pandemic, with 1 million new TB cases every year, accounting for 11% of all new cases globally. Two national surveys of tuberculosis prevalence in 1990 and 2000 showed that levels of TB were reduced by around 30% in the 13 provinces where the DOTS programme was adopted. However, national TB prevalence fell by just 19% over the decade.

Another survey was done in 2010 to re-evaluate the national TB burden, providing an opportunity to assess the effect of the nationwide expansion of the DOTS programme. Nearly 253 000 individuals aged 15 years and older were surveyed in 2010 at 176 investigation points chosen from all 31 mainland provinces. The results show that between 2000 and 2010, national TB prevalence fell by 57%tripling the reduction of the previous decade.

During this time, 87% of the total decrease in prevalence was among cases already diagnosed with TB before the survey. The increase of known TB cases treated using DOTS rose from 15% in 2000 to 66% in 2010, and contributed to lower proportions of treatment default (from 43% to 22%) and retreatment (from 84% to 31%).

According to the authors, "The DOTS programme has been much more effective in reducing the prevalence of tuberculosis in known cases than in new cases. Because the prevalence in known cases is already very low, future reduction in tuberculosis prevalence is likely to slow substantially unless control efforts in addition to the DOTS strategy are implemented, especially in earlier case detection and treatment and use of new instruments."

Writing in a linked Comment, Giovanni Battista, Director of the WHO Collaborating Centre for Tuberculosis and Lung Diseases in Italy, and Giovanni Sotgiu from the University of Sassari-Research in Italy, point out that because many developing countries have already improved TB treatment using the DOTS strategy, "Long-term, rapid reduction in the tuberculosis burden leading to tuberculosis elimination will need additional efforts, including adoption of new instruments in diagnosis (rapid molecular testing for drug-susceptible and drug-resistant tuberculosis) and treatment (new drugs effective against drug-resistant cases), systematic diagnosis and treatment of latent tuberculosis infection, and better access to care by high-risk populations (including free diagnosis and treatment, and social protection mechanisms preventing income loss)."


'/>"/>

Contact: Yu Wang
wangyu@chinacdc.cn
86-105-890-0001
The Lancet
Source:Eurekalert

Related medicine news :

1. Chinas reliance on lower-paid contract nurses may compromise patient care
2. China Biometric Access Controller Manufacturer SWAccessControl.com Announces A Special Offer On Its Biometric Fingerprint Scanners And Fingerprint Scanners
3. Global Sealant Industry & China Aerogel Market Size Analysis in New Research Reports at DeepResearchReports.com
4. China Laser Equipment Industry Production Capacity to Be 2.77 Times More by 2017 in a New Study at MarketReportsChina.com
5. China RFID Product Supplier SWAccessControl.com Introduces its UHF RFID Readers and RFID Antennas
6. China Digital Radiography Industry & Global CBCT Market Analysis in a New Research Study Available at DeepResearchReports.com
7. 2014 Vitamin C and Vitamin A Market China Global Analysis in a New Research Available at Deepresearchreports.com
8. China Door Access Control System Manufacturer Introduces Its RFID Reader Collection
9. Solid Fir Wood Caskets Now Offered By China Casket Manufacturer MillionaireCasket.com
10. Global and China Monoclonal Antibody Industry Report 2013 Analysis and 2017 Market Focus by Researchmoz.us
11. China Medical Monitor Industry 2013 Analysis & 2015 Forecasts in New Research Report at ChinaMarketResearchReports.com
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, ... Elite. The attorneys chosen by their peers for this recognition are considered among the ... Traurig Shareholders received special honors as members of this year’s Legal Elite Hall of ...
(Date:6/24/2016)... Plano, TX (PRWEB) , ... June 24, 2016 , ... ... taking part in Genome magazine’s Code Talker Award, an essay contest in which patients ... for an award to be presented at the 2016 National Society of Genetic Counselors ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital Partners, ... economy by obtaining investment capital for emerging technology companies. SCP has delivered ... already resulted in more than a million dollars of capital investment for five ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the upcoming 2016 Miss Arizona pageant as its official Medspa Sponsor. Dr. Josh ... Mesa, and Chandler, Arizona. , Dr. Olson says the decision to support ...
(Date:6/24/2016)... New York (PRWEB) , ... June 24, 2016 , ... ... marijuana patients optimize the ingestion of their medication by matching users with high quality ... users to compare pieces with no commitment. , Inhale was founded by two brothers, ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Global Blood Therapeutics, Inc. (GBT) (NASDAQ: ... novel therapeutics for the treatment of grievous blood-based ... closing of its previously announced underwritten public offering ... public offering price of $18.75 per share. All ... by GBT. GBT estimates net proceeds from the ...
(Date:6/24/2016)... June 24, 2016 The Academy of Managed ... recommendations that would allow biopharmaceutical companies to more ... that make formulary and coverage decisions, a move that ... new medicines. The recommendations address restrictions in ... on the drug label, a prohibition that hinders decision ...
(Date:6/24/2016)... 2016 According to a new ... Pen Needles, Safety Pen Needles), Needle Length (4mm, 5mm, ... Mode of Purchase (Retail, Non-Retail) - Trends & Global ... the market for the forecast period of 2016 to ... Billion by 2021 from USD 1.65 Billion in 2016, ...
Breaking Medicine Technology: