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The Journal of Nutrition Publishes Study Indicating that AHCC(R) Provides Immune Support against West Nile Virus

Results demonstrate potential for AHCC(R) in individuals living with West Nile Virus or susceptible populations such as the elderly or immune compromised

PURCHASE, N.Y., Feb. 23 /PRNewswire/ -- A study published online from The Journal of Nutrition (2009 Jan 13.) has demonstrated that AHCC(R) (Active Hexose Correlated Compound) enhances host resistance by boosting protective immune responses specific to West Nile Virus. This study is an important initial finding indicating that dietary supplements containing AHCC may be beneficial for individuals living with West Nile Virus.

West Nile Virus is a major public health concern that has been closely monitored by U.S. government agencies. The virus can cause brain inflammation (encephalitis) and is transmitted to humans by infected mosquitoes. According to the Centers for Disease Control and Prevention (CDC), there have been 28,975 reported cases with 1,124 deaths since 1999. In 2003, the highest number of cases was reported at nearly 10,000. Currently there is no effective treatment for the disease.

"Our results indicate that AHCC increases several critical immune responses associated with protecting the body from West Nile Virus," said Tian (Tina) Wang, Ph.D., lead researcher for the study and Assistant Professor, University of Texas Medical Branch at Galveston. "This study shows that AHCC may provide benefits against the West Nile Virus infection and demonstrates its role for immune system enhancement."

The West Nile Virus study utilizing AHCC examined its effect in both young and aged mice infected with a potent strain of West Nile Virus. AHCC was administered both prior to and post infection at specific intervals. Blood was drawn and analyzed for key parameters such as IgM (Immunoglobulin M) and IgG (Immunoglobulin G) antibody levels as well as gamma delta T cells. Increasing these responses helps the body protect itself from the virus. Results from the study demonstrated that AHCC increased the production of West Nile Virus-specific IgM, IgG and gamma delta T cells in young mice. Producing higher levels of these critical antibodies and lymphocytes is essential in helping the immune system protect itself from infection. AHCC also had an effect in aged mice but it was not as strong as on young mice. This initial study suggests that AHCC enhances protective immune responses against West Nile Virus infection in young and aged mice. Although additional studies are needed, these results are promising for individuals living with the disease as well as West Nile Virus susceptible populations such as the elderly and those individuals with a weakened immune system.

AHCC has been the subject of over 80 research studies worldwide. Research has demonstrated that AHCC enhances the immune system proving beneficial for a number of diseases that include flu, cancer, and autoimmune diseases.

What is AHCC (Active Hexose Correlated Compound)?

AHCC is derived from the hybridization of several subspecies of medicinal mushroom, cultivated in Japan and then produced from a specialized manufacturing process. AHCC is the leading immune-enhancing supplement in Japan and is utilized by over 700 hospitals and healthcare facilities worldwide as a standard preventative supplement for incoming patients to help reduce the risk of hospital infections as well as supporting the body's fight against the formation of abnormal cells.*

AHCC is manufactured by Amino Up Chemical Company in Sapporo, Japan and is distributed in the United States by Maypro Industries. Maypro sells AHCC to a number of leading supplement companies including Quality of Life Laboratories, a subsidiary of Maypro.

The AHCC Research Association was founded in 1986 to promote further study. Each year since 1994, over 300 medical doctors and researchers have gathered in Sapporo, Japan for the AHCC Research Association Symposium to share and discuss the latest developments.

To learn more about AHCC, visit the AHCC Research Association Web site at

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or mitigate disease.

SOURCE AHCC Research Association
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