Navigation Links
The Interplay of Kinase Broad Profiling and Phenotypic Screening Discussed in DiscoverX Webinar
Date:11/9/2016

Kinases play important roles in many biological signaling pathways, as an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates. Kinase inhibitors are, therefore, potentially found as actives in typical phenotypic screens.

DiscoverX is sponsoring a free webinar on the interplay of kinase broad profiling and phenotypic screening, which will provide details on the design of the Janssen kinase inhibitor broad profiling project and its impact on general early kinase drug discovery projects.

The team at Janssen Research & Development will be sharing two examples during this webinar, the mouse embryonic stem cell stemness assay, run in collaboration with Dundee DSTT, and the literature reported splicing corrector assay of pre-Lamin A. They will share results of how kinase inhibitor broad profiling and chem-bioinformatic analyses developed in the IMI OpenPhacts consortium can impact target deconvolution after phenotypic screening. The outcomes of these analyses are lists of potential kinase targets for further biological validation.

DiscoverX has arranged for Dr. Edgar Jacoby, senior principal scientist in computational chemistry at Janssen Research & Development, to be the presenter during this webinar.

Jacoby received his doctorate in computational chemistry from RWTH Aachen University, before doing post-doctoral work in molecular biophysics at Harvard Medical School and the University of Chicago. In 2013, he joined Janssen Research & Development as a senior principal scientist in computational chemistry. Prior to joining Janssen Research & Development, Jacoby worked at Servier doing research framework in molecular modeling. He has also worked at the Combinatorial Chemistry Group at Novartis Central Technologies as lab head for the in-silico design of combinatorial compound libraries, as well as led the Molecular and Library Informatics Group in the Novartis Center of Proteomic Chemistry in Basel from 2002 to 2012.

LabRoots will host the webinar December 7, 2016, beginning at 9:00 a.m. PT, 12:00 p.m. ET. To learn more about this event, or to register for free, click here.

About DiscoverX
DiscoverX Corporation, headquartered in Fremont, CA, USA, is a leader in the design, manufacture and sale of biochemical and cell-based assays for the drug discovery & life science markets. This industry-leading portfolio of products and services, under the KINOMEscan®, PathHunter® and BioMAP® brands, are used to aid life science research and enable rapid development of safe and effective biologic and small molecule drugs, by improving research productivity, effectiveness of screening, lead optimization & bioanalytical campaigns, as well as providing predictive tools that deliver physiologically relevant insights on drug molecules from early discovery through pre-clinical development. DiscoverX embodies an innovative approach to creating life science tools that have been widely adopted across the globe in pharmaceutical, biotechnology and academic laboratories.

About LabRoots
LabRoots is the leading scientific social networking website and producer of educational virtual events and webinars. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

Read the full story at http://www.prweb.com/releases/2016/11/prweb13819545.htm.


'/>"/>
Source: PRWeb
Copyright©2016 Vocus, Inc.
All rights reserved


Related medicine news :

1. Development of a novel dual JAK/Src kinase inhibitor
2. Global and Chinese Enterokinase Industry 2009-2019 Market Research Report Now Available at RnRMarketResearch.com
3. Broad-Connect Telecom Introduces Essential Voice SIP, Long Distance SIP and Toll-Free SIP
4. Human Circuit Completes Town of Vienna’s Council Chambers and Live Cable TV Broadcasting Project
5. My Positive Perspective Broadcasts Episode to Show Appreciation for Living in the Charleston, South Carolina area.
6. San Francisco's Top Pacific Heights Apartments for Rent, 2000 Broadway Apartments, to Participate in Trinity Management Job Fair
7. Targets of anticancer drugs have broader functions than what their name suggests
8. Operation Walk Utah Performs 60 Joint Replacement Surgeries Abroad at No Cost to Patients
9. My Positive Perspective Broadcasts Episode to Highlight the My Positive Perspective Radio Show on Kinetic Hifi
10. Forbes Living to Broadcast a Beneficial Senior Fitness Segment
11. My Positive Perspective Broadcasts Episode Speaking About Another Radio Show on Kinetic Hifi
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2019)... Ore. (PRWEB) , ... September 18, 2019 , ... A new study by BestPlaces looks ... . Same-sex marriage is the only Federally-mandated right, so other related rights vary widely across ... Conversion Therapy (trying to change an individual's sexual orientation) , Employment , ...
(Date:9/17/2019)... ... September 17, 2019 , ... ... Keflezighi and the American Heart Association (AHA)-San Diego Chapter to raise awareness of ... Stroke Walk on Saturday, September 21 in Balboa Park alongside National University System ...
(Date:9/17/2019)... , ... September 17, 2019 , ... ... initiative contributing to the long-term health of canines – specifically golden retrievers - ... Golden Retrievers will die from cancer – one out of five retrievers in ...
(Date:9/17/2019)... , ... September 17, 2019 , ... ... join the largest accountable care organization (ACO) in the country, the company announced ... groundbreaking collaboration to improve care quality and increase cost efficiency. This opportunity is ...
(Date:9/17/2019)... ... September 17, 2019 , ... Dr. Perry ... has been certified by the American Academy of Facial Esthetics (AAFE) to administer ... wide range of orofacial conditions such as tooth clenching and grinding, tongue tension, ...
Breaking Medicine News(10 mins):
(Date:9/17/2019)... ... September 17, 2019 , ... Dr. Arta Farahmand welcomes patients ... An alternative to conventional orthodontics, the Wilckodontics orthodontic system often cuts treatment time ... orthodontics uses brackets and wires that apply constant pressure on the teeth, thus ...
(Date:9/17/2019)... ... September 17, 2019 , ... Gustavo Grodnitzky, PhD will ... conference on Yoga Science as holistic mind/body medicine for physicians and other health care ... held October 22-26, 2019 at the Cranwell Resort and Spa in Lenox, Massachusetts, is ...
(Date:9/14/2019)... ... September 13, 2019 , ... Corey Stern , a partner at Levy ... Reginald Archibald over at least 3 decades while employed by Rockefeller University Hospital ... District Court - Southern District of New York, No. 1:19-cv-01403), the first case filed ...
Breaking Medicine Technology: