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The International Meeting for Autism Research (IMFAR)
Date:5/14/2014

y unpleasant touch and sound. In particular, the brain areas that were hyperactive included areas responsible for processing sound and touch (the primary auditory and somatosensory cortices), areas responsible for recognizing saliency and novel and/or unpleasant events (striatum), and areas responsible for emotion processing (amygdala, hippocampus, and orbital frontal cortex). Even more striking than the group differences was the finding that youth with autism whose parents reported higher SOR symptoms had higher activation in these brain areas. As such, youth with SOR may constitute a subgroup of individuals with autism who both initially respond too strongly to sensory stimuli but also fail to regulate their subsequent emotional response to the stimuli.

Emerging patterns of repetitive behavior linked to clinical and behavioral outcomes in high-risk infant siblings -- Jason J. Wolff1, Jed T. Elison2, Heather C. Hazlett1, Juhi Pandey3, Sarah J. Paterson3, Kelly N. Botteron, Annette M. Estes, Lonnie Zwaigenbaum4, Joseph Piven1, & the IBIS Network, 1University of North Carolina at Chapel Hill, 2University of Minnesota, 3Children's Hospital of Philadelphia, 4University of Alberta.

Restricted and repetitive behaviors are a core symptom of autism. These behaviors can range from arm and hand flapping to insistence on a set routine or limited set of interests and activities. Our longitudinal study focused on how these behaviors unfold very early in the lives of children at-risk for autism. We tracked profiles of restricted and repetitive behaviors in 243 toddlers at low- and high-risk for autism from ages 12 to 24 months using a parent-report measure. We found that all forms of restricted and repetitive behavior were significantly increased in children who developed autism. These differences were evident starting at age 12 months, years before the average age of diagnosis. Children with elevated repetitive behavior at age 12 months were 4 times m
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Contact: Adam Pockriss
apockriss@rubenstein.com
212-843-8286
Rubenstein Associates, Inc.
Source:Eurekalert

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