Navigation Links
The International Meeting for Autism Research (IMFAR)
Date:5/14/2014

n occurring at 18 months. When we mathematically transformed these "growth curves" to identify when this process began in development i.e., when there was a change in the dynamic of the trajectory we could pinpoint a shift in rate of change in eye fixation to the 9th month of life in these children. These results suggest a period of malleability in this phenomenon, with some children naturally undergoing course correction. If so, this early period of plasticity might be capitalized upon for early treatment and intervention with the goal of fostering such "course correction" in a larger number of children at greater genetic risk for ASD.

Insulin-like growth factor-1 rescues synaptic and motor deficits in a mouse model of autism and developmental delay -- J. D. Buxbaum, Seaver Autism Center for Research and Treatment, Department of Psychiatry, Icahn School of Medicine at Mount Sinai.

SHANK3 gene deletions and mutations result in Phelan McDermid Syndrome (PMS) and cause ASD with a frequency of 0.5% of ASD cases. Loss of SHANK3 is sufficient to cause the syndrome and is known to produce significant disruption in nerve cell function and plasticity in animal models. Our recent evidence from preclinical studies with mouse models of SHANK3 deficiency indicates that Insulin-Like Growth Factor-1 (IGF-1) can reverse synaptic plasticity and motor learning deficits at clinically approved doses. More recently another group has shown beneficial effects of IGF-1 in human nerve cells carrying SHANK3 mutations. IGF-1 is a commercially available therapeutic compound that enters the brain and has beneficial effects on nerve development by promoting nerve cell survival, synaptic maturation, and synaptic plasticity. We have now carried out a pilot study of IGF-1 treatment in nine patients with PMS (ages 5-15) in order to evaluate safety, tolerability, and efficacy for core deficits of ASD, including social impairment and restricted and repetitive behaviors.
'/>"/>

Contact: Adam Pockriss
apockriss@rubenstein.com
212-843-8286
Rubenstein Associates, Inc.
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. International breast health global summit will focus on supportive care and quality of life
2. International conference to explore health of descendants of transatlantic slave trade
3. Kessler Foundation researchers present at first International Congress on Cognition in MS
4. Internationally known expert in ovarian cancer to be honored at the ASCO Annual Meeting
5. Nobel laureate to keynote international pharmaceutical conference at URI
6. International Nanomedicine Conference bound for Sydney: July 2-4, 2012
7. June 2012 marks a milestone for International Urogynecology Associates as Dr. Robert D. Moore and Dr. John R. Miklos perform their 24th Neovagina Surgery in 24 months
8. Heavy Duty Alternators and Starters Expert Elreg Distributors Ltd. Meets Needs of International Market with Launch of Spanish Website
9. The US Drug Watchdog Now Urges Plaintiffs Law Firms Worldwide To Contact Them About A Possible International Effort To Help Victims Of Defective Drugs Or Medical Devices
10. RMAX International to donate Recuper8 - a free, health - restoring program to Everyone in Uniform
11. International symposium on veterinary rehabilitation and physical therapy to be held in Vienna
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... (PRWEB) December 26, 2014 The ... Analysis to 2023” focuses on the current treatment ... in the colorectal cancer market. Stivarga is a ... colon or rectal cancer. Boehringer Ingelheim is developing ... the treatment of refractory CRC in the US, ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... When head lice hits a home or school, parents ... rid of it while keeping it from taking over the ... the solution right in their neighborhood: Lice Troopers . ... full spectrum head lice screening and treatment services to families ... Biscayne, Brickell, Coconut Grove, Kendall, Pinecrest and South Miami. , ...
(Date:12/25/2014)... 2014 (HealthDay News) -- Among early stage breast cancer ... half of one percent will eventually develop leukemia as ... The finding comes from a review of more ... 2007, and it suggests that the risk for developing ... had previously thought. "The frequency of bone marrow ...
(Date:12/25/2014)... December 25, 2014 Plugin creators from ... 5k. A fully customizable business presentation tool made specifically ... the ProFire 5k business tool, users can now display ... CEO of Pixel Film Studios. “ProFire 5k gives users ... to add professionalism to a presentation” , Pixel Film ...
Breaking Medicine News(10 mins):Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 3Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2
... . , Montreal, January 14, 2009 Canadian researchers ... cancer. According to a recent study from the Universit de ... Journal of Biological Chemistry , the protein ARF1 plays a ... tumours. Targeting this protein with drug therapy may provide hope ...
... Only Non-Drowsy Allergy Medicine in a Liquid-Filled Capsule ... 14 Schering-Plough Corporation (NYSE: SGP ... Liqui-Gels(R), the first and only non-drowsy allergy medicine ... CLARITIN(R) Liqui-Gels(R) provide powerful liquid relief for the ...
... affected by chronic inflammation without knowing much about it. FlameEz.com is ... inflammation, the root cause of many of the most feared illnesses ... ... PA (PRWEB) January 14, 2009 -- Millions of Americans are affected ...
... N.C., Jan. 14 Germs are everywhere,and especially dangerous ... can age hands, ignite near flame and make kids ... www.remi-d.com ) dispenses with these maladies with subtle,scents, convenience ... sanitizers have been sick with laziness. Remi-D is ...
... Va., Jan. 14 ... solutions for healthcare, announced that the Unbound(TM) Platform ... iPod(R) touch devices. Adding delivery of iPhone applications ... Palm OS devices strengthens Unbound Medicine,s position as ...
... Specialty Line for Tweens and TeensCARLSBAD, Calif., Jan. 14 ... ages clarifying products that are 100% natural and ultra-effective ... The products include the Everyday Clarifying Lotion, Everyday Clarifying ... be debuting at the New York International Gift Fair, ...
Cached Medicine News:Health News:New Non-Drowsy CLARITIN(R) Liqui-Gels(R) Now Available 2Health News:New Non-Drowsy CLARITIN(R) Liqui-Gels(R) Now Available 3Health News:Control of Inflammation May Benefit Many of the Most Feared Illnesses in Middle and Old Age 2Health News:Control of Inflammation May Benefit Many of the Most Feared Illnesses in Middle and Old Age 3Health News:No Germs, No Fires, No Mess: New Product Makes Good Health Easy and Natural 2Health News:Unbound Medicine Announces Download Support for iPhone(TM) and iPod(R) Touch Devices 2Health News:Glory for Girls Announces All-Natural Clarifying Products for Clear and Radiant Skin 2
(Date:12/24/2014)... , Dec. 23, 2014  Medical Science Liaisons ... the key link between the medical device industry and ... more in the coming years as the device industry ... According to research by benchmarking firm, Best Practices, ... gain an important edge is by harnessing new technology ...
(Date:12/22/2014)... , Dec. 22, 2014   TRU-D SmartUVC ... no-touch UV disinfection robot, announced today that the General ... contract through November 2019.   This newly ... engage all levels of government purchasers, including Department of ... well as Homeland Security contacts purchasing solutions for the ...
(Date:12/22/2014)... MARLBOROUGH, Mass , Dec. 22, 2014 /PRNewswire/ -- ... a biotechnology company focused on discovering, developing and ... using RNA-targeted technologies, today issued the following open ... Geert Cauwenbergh , Dr. Med. Sc. ... few days a number of inaccurate statements posted ...
Breaking Medicine Technology:Role of Medical Science Liaisons Evolving in Medical Device Sector 2TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2RXi Pharmaceuticals Issues Open Letter to Shareholders 2RXi Pharmaceuticals Issues Open Letter to Shareholders 3RXi Pharmaceuticals Issues Open Letter to Shareholders 4RXi Pharmaceuticals Issues Open Letter to Shareholders 5RXi Pharmaceuticals Issues Open Letter to Shareholders 6
... Inc.(Nasdaq: MSHL ), an oncology company focused on ... today that it will host its Annual Meeting of Stockholders ... offices of Morgan, Lewis & Bockius LLP, located at 101 ... vote on certain matters, including the approval of the transactions ...
... 10, 2011 Eli Lilly and Company (NYSE: ... Ph.D., will lead Lilly,s oncology research efforts as the vice ... research. In this innovative new role created by ... of both Lilly and its subsidiary, ImClone. Plowman will be ...
Cached Medicine Technology:Marshall Edwards to Host Annual Meeting of Stockholders 2Marshall Edwards to Host Annual Meeting of Stockholders 3Lilly Announces New Vice President of Oncology Research 2Lilly Announces New Vice President of Oncology Research 3
... of flexible lighting products. The first is ... different sizes 5", 10", and 15" (refers ... light). These lights are for use in ... ,The second group of flexible lights is ...
... two groups of flexible lighting products. The ... in three different sizes 5", 10", and ... of the light). These lights are for ... needed., ,The second group of flexible ...
... Aaron manufactures two groups of flexible lighting ... and non-sterile in three different sizes 5", ... shaft portion of the light). These lights ... light is needed., ,The second group ...
Designed to be used for neuromuscular blockage monitoring. Provides for easy placement over the ulnar nerve on a patient's wrist. Dual element permits non-invasive monitoring using a single electrode...
Medicine Products: