Navigation Links
The Huntington Study Group announces first-HD study
Date:6/21/2013

The Huntington Study Group (HSG), under the leadership of Samuel Frank, MD, Principal Investigator, (Boston University School of Medicine) and Claudia Testa, MD, PhD, co-Principal Investigator (Virginia Commonwealth University), is conducting a clinical trial with a formulation of the novel drug SD-809 in the treatment of HD the United States and Canada. The trial is sponsored by Auspex Pharmaceuticals, Inc. who is developing the drug for the treatment of Huntington disease, as well as Tourette syndrome and tardive dyskinesia.

First-HD is a randomized, double blind, placebo controlled study that examines the efficacy, safety and tolerability of a formulation of the investigational drug known as SD-809 for the treatment of chorea associated with Huntington Disease. The drug has the same mechanism of action as the FDA approved drug tetrabenazine that is used to lessen chorea in people with HD, an inherited disease that affects over 30,000 people in both the United States and Canada. HD is characterized by brain cell death that usually begins between the ages of 30 to 50. This cell loss results in motor, cognitive and behavioral signs and symptoms. Chorea, which is characterized by involuntary movements, is a hallmark of the disease.

Because SD-809 is more slowly metabolized than tetrabenazine, it provides more consistent and predictable drug levels and can be given less often than tetrabenazine. With these changes, a lower overall dose of SD-809 can be administered and it may be more convenient for persons with HD. This study will test the efficacy, safety and tolerability of a formulation of SD-809 in the management of chorea symptoms in HD patients who have not previously taken tetrabenazine. Participants will be involved in this trial for approximately 4 months.

Dr. Samuel Frank, the Principal Investigator of First-HD notes that "we are excited to work with Auspex to investigate the efficacy, safety and tolerability of this i
'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Huntingtons Disease Linked to Reduced Cancer Risk in Study
2. Researchers restore neuron function to brains damaged by Huntingtons disease
3. Reach2HD, a Phase II study in Huntingtons disease, launched
4. Device implanted in brain has therapeutic potential for Huntingtons disease
5. Proposed drug may reverse Huntingtons disease symptoms
6. Well-known author and historian reports on progress in Huntingtons therapies
7. Human model of Huntingtons disease created from skins stem cells
8. Scientists Use Stem Cells to Mimic Huntingtons Disease
9. First Huntingtons disease center established in Washington, D.C., area
10. Cell loss in the brain relates to variations in individual symptoms in Huntingtons disease
11. NIH funds UT Dallas study on cause of Huntingtons disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Lambda Solutions, a leader in cloud-based ... to welcome Stewart Rogers on board as the ... Lambda Solutions comments, “Product leadership will take Lambda to the ... so. Learning and talent management is at a pivotal moment ... learning and talent development in the past ten years so ...
(Date:9/16/2014)... ADW Diabetes has teamed up with the Durham Diabetes ... diabetes testing supplies to people in the local ... these much needed supplies to maintain their health. , ... free diabetes information to the community of Durham. It ... have diabetes, many of them not knowing that they do. ...
(Date:9/16/2014)... 2014 Recently, UWDress.com, an outstanding online ... has announced its special offer for cocktail gowns ... cocktail dresses at a low rate. More importantly, all ... shipping cost. , UWDress.com has promised to provide ... able to find the most fashionable items. The company ...
(Date:9/16/2014)... 2014 The rapidly increasing cost of ... plans, employers and PBMs as spending on these specialized ... lists. Once a concentrated, patient-specific practice, compounding has become ... Atlantic Information Services, Inc. (AIS), “Controlling the Cost ... details of what one leading health insurer and its ...
(Date:9/16/2014)... Dakota Software , a ... and Sustainability management software, today announced that it ... software platform, MobileWorkflows, at their Annual Users Conference ... allow for on-the-go access to Dakota’s enterprise-level software ... Web Design, MobileWorkflows feature a streamlined user interface, ...
Breaking Medicine News(10 mins):Health News:Stewart Rogers Joins Lambda Solutions as Director of Product Management 2Health News:Stewart Rogers Joins Lambda Solutions as Director of Product Management 3Health News:ADW Diabetes Joins Forces with Durham Diabetes Coalition to Help Local Community 2Health News:ADW Diabetes Joins Forces with Durham Diabetes Coalition to Help Local Community 3Health News:UWDress.com: Cheap Cocktail Gowns For The Global Market 2Health News:Sept. 25 Webinar to Offer Health Plan, Employer Strategies to Control Compounded Medication Costs 2Health News:Mobile EHS Compliance Tools the Focus of Dakota Software’s 2014 Users Conference 2
... long been the factor most commonly used to predict ... four additional factors that can help predict a preemies ... Health Neonatal Research Network, of which Yale is a ... is a twin and whether the mother was given ...
... The cost of cancer care for elderly Medicare patients varies ... survival, according to a new study published online April 29 ... The 5-year cost is highest for patients with lung, colorectal, ... care for elderly Medicare patients diagnosed with cancer in 2004 ...
... Young Internet-using men who have sex with men AND ... numbers of partners, appear more likely to contract HIV, and report ... online or offline, according to new research at the University of ... A greater percentage of the group reported unprotected ...
... Two New York University professors, Helmut Hofer of NYUs ... of the universitys Center for Neural Science, have been ... D.C.-based organization announced today. , Hofer and Movshon were ... from nine countries who were elected in recognition of ...
... And perhaps more importantly, who should be charged with ... physician? , Elisa Hurley, a philosophy professor, is seeking ... at The University of Western Ontario. , In the ... a fictional, non-surgical procedure called targeted memory erasure is ...
... Looming Closures, Layoffs and Loss of Healthcare Services, ... services. Longer drives and longer waits for care.,Those are ... for if,the state,s $300 million in proposed healthcare cuts ... nearly 100 healthcare leaders from across,the state met with ...
Cached Medicine News:Health News:Factors affecting survival, disability of extremely premature infants identified 2Health News:Medicare costs estimated to top $21.1 billion for 5 years of care for elderly cancer patients 2Health News:U of M study: Online intervention paramount for reducing HIV in high-risk population 2Health News:Moral philosopher questions memory manipulation 2Health News:Hospital CEOs Meet with Governor on Budget Cuts 2
(Date:9/15/2014)... , Sept. 15, 2014  Patients in today,s ... care more frequently in an outpatient setting versus a ... curve and to ensure that patients continue to receive ... the launch of its new internal medicine residency program. ... more often in office, clinic and even virtual settings. ...
(Date:9/15/2014)... , Sept. 15, 2014  Valeant Pharmaceuticals International, Inc. ... its wholly owned subsidiary, Valeant Pharmaceuticals International, will redeem ... of its 6.75% Senior Notes due 2017, CUSIP Nos. ... 2014 and has mailed an irrevocable notice of redemption ... a copy of the irrevocable notice of redemption with ...
(Date:9/15/2014)... , Sept. 15, 2014 myMatrixx has extended ... Stanos with an expanded role that includes direct ... Dr. Stanos, a nationally recognized physiatrist and pain management ... to rehabilitation and workers, compensation, is Board Certified in ... American Board of Pain Medicine and subspecialty boarded by ...
Breaking Medicine Technology:Kaiser Permanente Hawaii Launches New Internal Medicine Residency Program 2Kaiser Permanente Hawaii Launches New Internal Medicine Residency Program 3Valeant Announces Redemption of All of the Outstanding $500.0 Million Aggregate Principal Amount of its 6.75% Senior Notes due 2017 2myMatrixx Announces Expanded Role for Medical Director Steven P. Stanos, Jr., DO 2
... 2009 Convention -- When Shawnae Jebbia won the Miss USA ... career. She appeared at events throughout the world, worked as ... world unexpectedly changed when she was diagnosed with hearing loss. ... had a difficult time understanding and accepting the sudden hearing ...
... eResearchTechnology, Inc. (ERT), (Nasdaq: ERES ), a leading provider ... medical device and related industries, announced today results for the ... Unless otherwise noted, all comparative numbers refer to changes from ... , Financial highlights for the third quarter of 2009: ...
Cached Medicine Technology:Former Miss USA Shawnae Jebbia Shines with Siemens Pure 2Former Miss USA Shawnae Jebbia Shines with Siemens Pure 3ERT Reports Third Quarter 2009 Results 2ERT Reports Third Quarter 2009 Results 3ERT Reports Third Quarter 2009 Results 4ERT Reports Third Quarter 2009 Results 5ERT Reports Third Quarter 2009 Results 6ERT Reports Third Quarter 2009 Results 7ERT Reports Third Quarter 2009 Results 8ERT Reports Third Quarter 2009 Results 9ERT Reports Third Quarter 2009 Results 10ERT Reports Third Quarter 2009 Results 11ERT Reports Third Quarter 2009 Results 12ERT Reports Third Quarter 2009 Results 13
The Empore 96 well plate vacuum manifold comes complete with waste tray, gasket and shims, may be used as a stand-alone or with 96-well automation....
QIAvac 6S provides all manifold components for processing QIAGEN 8-well strips....
For processing mini spin columns on QIAvac 6S;...
Replacement gaskets for the Empore 96 Well Vacuum Manifold Assembly, insure a tight seal....
Medicine Products: