Navigation Links
The GenoMEL project identifies a new region of the genome associated with the risk of melanoma
Date:7/6/2009

Research is increasingly becoming a networked process. The big genome studies are a good example of the need to pool the efforts of gold standard centers around the world. Only in this way is it possible to achieve results as solid as those obtained by the GenoMEL project, which is funded by the European Commission to study the genetic and environmental risk factors for melanoma. The objective is to translate this knowledge into recommendations based on evidence and healthier habits. The latest results obtained by this project, to published Online on Sunday in the journal Nature Genetics, have found a link between the risk of melanoma and two regions associated with skin pigmentation and a new region of the genome. GenoMEL is led by Leeds University and the IDIBAPS - Hospital Clnic of Barcelona researchers Dr. Susana Puig and Dr. Josep Malvehy are the only Spanish authors of this article.

Single-nucleotide polymorphisms (SNPs) are small variations in the sequence of nucleotides that make up DNA and can be associated with many genetic diseases. The study published in Nature Genetics performs an exhaustive search for SNPs in a broad population sample. The study enrolled 4336 control subjects and 1650 patients with melanoma and probable unknown genetic susceptibility. That is, patients with familial melanoma, multiple melanoma or melanoma before the age of 40 years who do not present mutations in the familial melanoma genes. The study was later replicated in a sample of 1163 patients and 903 controls in order to increase the solidity of the results. The statistical studies identified three regions in the genome with variations that represent a risk of developing melanoma. Two of these regions form part of the genes TYR and MCR1, associated with skin pigmentation and sensitivity to sunlight; they had already been identified in previous studies as risk factors. The third region is on chromosome 9 and represent
'/>"/>

Contact: lex Argem, Scientific editor
aargemi@clinic.ub.es
34-932-275-700
IDIBAPS - Institut d'Investigacions Biomdiques August Pi i Sunyer
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Wounded Warrior Project (WWP) Seeks to Provide Mind, Body and Spirit Healing for Combat Stress
2. Allegiant Professional Business Services Inc. Signs New Members to Its PPO Health Insurance Plan. Annual Revenues Projected to Increase by $5M.
3. Kiwanis International Pursuing Second Worldwide Service Project
4. Marathon and Partners Announce Dramatic Results of Malaria Control Project on Bioko Island in Equatorial Guinea
5. Cardin Calls on NIH to Utilize Small Businesses for Extramural Research Projects
6. Parent Project Muscular Dystrophy Holds 15th Annual Connect Conference in Atlanta
7. First Lady Michelle Obama and California First Lady Maria Shriver Kick Off 2009 National Conference on Volunteering & Service with Playground Service Project
8. McGill University receives almost $63 million under CFI program to support 5 research projects
9. National Council on Aging and Medicare Diabetes Screening Project Launch New Program to Educate Seniors about Medicares Benefits for Diabetes Screening
10. Wounded Warrior Project (WWP) Expands Board of Directors
11. Medicare, NW Denver Partners Launch Care Transitions Project
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... HealthDay Reporter THURSDAY, Oct. 30, 2014 (HealthDay ... is nothing new. The first kidney transplant took place ... and the first human heart transplant in 1967. By 2010, ... face. One major organ still eludes the transplant surgeon, ... U.S. scientists has its way, that dream may become reality, ...
(Date:10/31/2014)... year, people across the United States spend an estimated ... which costs $522 billion, according to new research. ... the time and wages that caregivers give up every ... daily activities. The study authors said the significant financial ... flexibility policies. "Our findings provide a new and ...
(Date:10/30/2014)... Einstein College of Medicine of Yeshiva ... their latest aging research at the Gerontological Society ... include the identification of a genotype that can ... the cellular biology of aging. GSA 2014 will ... "Einstein-Montefiore has distinguished itself in a range of ...
(Date:10/30/2014)... research group at the DFG Research Center for Regenerative ... Dresden (CRTD) demonstrated for the first time the in ... three dimensions from mouse embryonic stem cells. Correct spatial ... the dorsal/ventral axis was observed., This study has been ... Cell Reports " on 30.10.2014 ., For many years ...
(Date:10/30/2014)... Graphics, coding, typography and search engine optimization– ... of web design and require thorough knowledge to create ... to create a website can be as easy as ... reviews and Facebook posts all accumulate on a multiple ... evolution of how a business can develop a website," ...
Breaking Medicine News(10 mins):Health News:Scientists Set Their Sights on First Whole-Eye Transplant 2Health News:Scientists Set Their Sights on First Whole-Eye Transplant 3Health News:'Informal Care' for Older Americans Tops $500B Annually, Study Finds 2Health News:Einstein-Montefiore investigators present aging research at Gerontological Society of America's Annual Scientific Meeting 2Health News:Einstein-Montefiore investigators present aging research at Gerontological Society of America's Annual Scientific Meeting 3Health News:Einstein-Montefiore investigators present aging research at Gerontological Society of America's Annual Scientific Meeting 4Health News:Reconstruction of a patterned piece of spinal cord in 3-D culture 2Health News:Facebook Websites In Thirty-Seconds 2
... clarify the disease,s connection to obesity , , TUESDAY, Dec. 30 ... their blood appear to be more likely to develop breast ... might be the link between obesity and breast cancer, say ... York City. High insulin levels have already been associated with ...
... variant had cancer as well as idiopathic pulmonary fibrosis, study ... mutation in a gene previously found to help protect the ... and some inherited cases of a lethal lung disease affecting ... in the SFTPA2 gene have been found in ...
... resident Gary Balady, MD, a cardiologist in the Division ... of medicine at the Boston University School of Medicine ... by Castle Connolly Medical Ltd. , The America,s Top ... is a trusted and authoritative resource for identifying top ...
... cruciate ligament (ACL) reconstruction can be difficult, but a review of ... edition of Sports Health: A Multidisciplinary Approach highlights how the use ... issues. , ... Rosemont, IL (Vocus) December 30, 2008 ...
... Treat Diseases (HTDS) www.htdsmedical.com (temporary site up ... it has registered with Pink Sheets for its back ... information including updating last 2 years financial statements. The ... a "Yield" rank from the current "STOP" no information ...
... with fish oil can improve health and cholesterol levels, however, new ... Approach highlights the effects of the omega fish oil on professional ... ... -- Researchers have firmly established that supplementing a diet with fish ...
Cached Medicine News:Health News:High Insulin May Boost Odds of Breast Cancer 2Health News:Gene Mutation Tied to Inherited Fatal Lung Disease 2Health News:BMC, Boston University School of Medicine cardiologist named 1 of America's Top Doctors 2Health News:Adding Eccentric Resistance Training Improves Muscle Strength Following ACL Surgery 2Health News:Adding Eccentric Resistance Training Improves Muscle Strength Following ACL Surgery 3Health News:Study Shows Fish Oils Dramatically Improve Cholesterol Levels in Professional Football Players 2Health News:Study Shows Fish Oils Dramatically Improve Cholesterol Levels in Professional Football Players 3
(Date:10/31/2014)... announces the list of stocks featured in the Analyst Blog. Every ... events impacting stocks and the financial markets. Stocks recently featured in ... Report ), Celgene (Nasdaq: CELG - Free Report ... ), Market Vectors Biotech ETF (AMEX: BBH - ... XBI - Free Report ). Today, Zacks is ...
(Date:10/31/2014)... 31, 2014 /CNW Telbec/ - Ergoresearch Ltd ... plan, for accelerated growth in terms of sales and ... reached $17,862,341. Net income amounted to $1,230,153. The EBITDA ... first time in the Company,s history. With ... the forces of its subsidiaries, merging in September 2014 ...
(Date:10/31/2014)... -- Though therapies are in their nascent phase, sales ... annual increase of 16.2% over the 2010-2020 period, reaching ... to Kalorama Information,s report, Stem Cell Therapeutics Markets ... have gained or are expected to gain approval from ... ever more complicated conditions, stem cell therapies hold the ...
Breaking Medicine Technology:The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 2The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 3The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 4The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 5The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 6The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 7Results for the fourth quarter and the fiscal year ended June 30, 2014 - Ergoresearch reports solid 2014 annual results 2Results for the fourth quarter and the fiscal year ended June 30, 2014 - Ergoresearch reports solid 2014 annual results 3Results for the fourth quarter and the fiscal year ended June 30, 2014 - Ergoresearch reports solid 2014 annual results 4Results for the fourth quarter and the fiscal year ended June 30, 2014 - Ergoresearch reports solid 2014 annual results 5Report: Stem Cell Technologies Market Growing 2
... 20 Santaris Pharma announced today that,the fourth ... In the USA,several patients with cancer have now ... jointly developed by Santaris Pharma and Enzon,Pharmaceuticals. The ... Pharma­ceutical,s Investigational New Drug (IND) application,for the use ...
... Expands Overseas TBI TrialCOSTA MESA, Calif., March 19 ... that the company has received a letter from the ... forward" as a basis to resume clinical studies of ... therapeutic oxygen carrier.The letter was in response to the ...
Cached Medicine Technology:Another LNA-based RNA Inhibitor Enters Clinical Trials 2Another LNA-based RNA Inhibitor Enters Clinical Trials 3Oxygen Biotherapeutics, Inc. Receives Letter From FDA Outlining Path Forward to Resume Oxycyte Clinical Trials in TBI in U.S.A. 2Oxygen Biotherapeutics, Inc. Receives Letter From FDA Outlining Path Forward to Resume Oxycyte Clinical Trials in TBI in U.S.A. 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: