Navigation Links
The GenoMEL project identifies a new region of the genome associated with the risk of melanoma
Date:7/6/2009

Research is increasingly becoming a networked process. The big genome studies are a good example of the need to pool the efforts of gold standard centers around the world. Only in this way is it possible to achieve results as solid as those obtained by the GenoMEL project, which is funded by the European Commission to study the genetic and environmental risk factors for melanoma. The objective is to translate this knowledge into recommendations based on evidence and healthier habits. The latest results obtained by this project, to published Online on Sunday in the journal Nature Genetics, have found a link between the risk of melanoma and two regions associated with skin pigmentation and a new region of the genome. GenoMEL is led by Leeds University and the IDIBAPS - Hospital Clnic of Barcelona researchers Dr. Susana Puig and Dr. Josep Malvehy are the only Spanish authors of this article.

Single-nucleotide polymorphisms (SNPs) are small variations in the sequence of nucleotides that make up DNA and can be associated with many genetic diseases. The study published in Nature Genetics performs an exhaustive search for SNPs in a broad population sample. The study enrolled 4336 control subjects and 1650 patients with melanoma and probable unknown genetic susceptibility. That is, patients with familial melanoma, multiple melanoma or melanoma before the age of 40 years who do not present mutations in the familial melanoma genes. The study was later replicated in a sample of 1163 patients and 903 controls in order to increase the solidity of the results. The statistical studies identified three regions in the genome with variations that represent a risk of developing melanoma. Two of these regions form part of the genes TYR and MCR1, associated with skin pigmentation and sensitivity to sunlight; they had already been identified in previous studies as risk factors. The third region is on chromosome 9 and represent
'/>"/>

Contact: lex Argem, Scientific editor
aargemi@clinic.ub.es
34-932-275-700
IDIBAPS - Institut d'Investigacions Biomdiques August Pi i Sunyer
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Wounded Warrior Project (WWP) Seeks to Provide Mind, Body and Spirit Healing for Combat Stress
2. Allegiant Professional Business Services Inc. Signs New Members to Its PPO Health Insurance Plan. Annual Revenues Projected to Increase by $5M.
3. Kiwanis International Pursuing Second Worldwide Service Project
4. Marathon and Partners Announce Dramatic Results of Malaria Control Project on Bioko Island in Equatorial Guinea
5. Cardin Calls on NIH to Utilize Small Businesses for Extramural Research Projects
6. Parent Project Muscular Dystrophy Holds 15th Annual Connect Conference in Atlanta
7. First Lady Michelle Obama and California First Lady Maria Shriver Kick Off 2009 National Conference on Volunteering & Service with Playground Service Project
8. McGill University receives almost $63 million under CFI program to support 5 research projects
9. National Council on Aging and Medicare Diabetes Screening Project Launch New Program to Educate Seniors about Medicares Benefits for Diabetes Screening
10. Wounded Warrior Project (WWP) Expands Board of Directors
11. Medicare, NW Denver Partners Launch Care Transitions Project
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2013)... Bournemouth, Dorset (PRWEB) June 20, 2013 ... disease) and more serious medical conditions because they do ... of Eludril mouthwash and Elgydium toothpaste. , Seven million ... leaving it 48 hours between brushes, latest data from ... per cent of people polled by the BDHF also ...
(Date:6/20/2013)... Michigan-based natural health and wellness coach ... Hamilton which revealed that performing random acts of kindness ... release of the feel-good hormone Oxytocin in the brain ... the ‘cardio protective’ hormone because it temporarily lowers blood ... , “Being kind is something we can all do, ...
(Date:6/20/2013)... (PRWEB) June 20, 2013 Startups who ... energize their sales or test new markets, and international ... now have a new sales outsourcing company ... sales revenue. , Strategy Sales Partners is ... Founded by business owners for business owners, Strategy Sales ...
(Date:6/20/2013)... Creighton University was named to the ... the highest federal recognition a college or university can ... and civic engagement as well as meaningful community outcomes. ... and Community Service, is given to 690 schools nationwide ... Creighton is based on spiritual growth through service to ...
(Date:6/19/2013)... With the winter season having begun ... winter season Santiago day trips schedule. Offering ... and around Santiago this season, expert mountain guides from ... for backcountry skiing, challenging rock climbing adventures, and trekking ... dreamed of skiing in Chile , Chile Montaña ...
Breaking Medicine News(10 mins):Health News:Millions Are Risking Gum Disease, Warn Eludril And Elgydium 2Health News:Millions Are Risking Gum Disease, Warn Eludril And Elgydium 3Health News:Kindness Can Be Good for The Heart Says BioGirl Health Show 2Health News:Kindness Can Be Good for The Heart Says BioGirl Health Show 3Health News:Strategy Sales Partners Launches to Provide Sales Outsourcing Assistance to Businesses 2Health News:Strategy Sales Partners Launches to Provide Sales Outsourcing Assistance to Businesses 3Health News:Creighton Again Named to President’s Honor Roll - University Picks Up Sixth Recognition Award for Service 2Health News:Creighton Again Named to President’s Honor Roll - University Picks Up Sixth Recognition Award for Service 3Health News:Chile Montaña Announces Winter Season Santiago Day Trips 2Health News:Chile Montaña Announces Winter Season Santiago Day Trips 3
... Canadian Study finds that adolescence boys are at higher risk ... Researchers have found that the seeds of hypertension and its ... management, lack of exercise, obesity are some of the factors ... in heart damages. ,In the study which began ...
... following an E. coli outbreak. In the last fortnight, at ... diarrhea. They were diagnosed with E coli infection. ... Inc in New Jersey have been incriminated as the most ... that they had eaten from one of the three Taco ...
... its annual meeting at Nashville on 4 th December. ... for// the need to move in a new direction ... ,The panel consisted of representatives from academics, ... the delay in the development of novel treatments for ...
... Academy of Pediatrics blames inappropriate advertising to be the ... government to impose bans and restrictions on// advertising to ... of New Mexico's Doctor and the lead author of ... ads per year on television alone and increasingly are ...
... health awareness in rural areas - puppets.// ... Raje last week informs the rural poor on the ... shows and cultural programmes. ,The month-long 'Swasthaya ... health-related information with the help of local artistes in ...
... have fast food outlets in their site, thus giving an ... reality it is not. According to a report in the// ... 200 hospitals had fast food outlets. ,Dr. Hannah ... two different messages by being in the health care profession ...
Cached Medicine News:Health News:Teen Boys At Greater Risk To High Blood Pressure Than Girls 2Health News:Research In A New Direction To Develop Innovative Psychotropic Drugs 2Health News:Research In A New Direction To Develop Innovative Psychotropic Drugs 3
(Date:6/19/2013)... , June 19, 2013 Pharmacyclics, Inc. ... that The New England Journal of Medicine ... 1b/2 study evaluating the investigational oral Bruton,s tyrosine kinase ... leukemia (CLL) or small lymphocytic lymphoma (SLL). Ibrutinib was ... relapsed/refractory CLL or SLL, even in patients who were ...
(Date:6/19/2013)... BELLEVUE, Wash. , June 19, 2013 ... Provisioning version 4.0, a solution designed to ... to applications and data while supporting their ... release of Provisioning represents a milestone in ... governance and analytics capabilities for health systems. ...
(Date:6/19/2013)... June 19, 2013 ... added DrugPatentWatch to its extensive list ...      (Logo: http://photos.prnewswire.com/prnh/20130128/590935) , ... on pharmaceutical, drug patents and their ... critical business functions of patent agents ...
Breaking Medicine Technology:Ibrutinib Study Results in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Published in The New England Journal of Medicine 2Ibrutinib Study Results in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Published in The New England Journal of Medicine 3Ibrutinib Study Results in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Published in The New England Journal of Medicine 4Ibrutinib Study Results in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Published in The New England Journal of Medicine 5Ibrutinib Study Results in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Published in The New England Journal of Medicine 6Caradigm Provisioning Helps Healthcare Organizations Improve Clinical Efficiency, Manage Risk 2Caradigm Provisioning Helps Healthcare Organizations Improve Clinical Efficiency, Manage Risk 3Drug Patent Watch 2Drug Patent Watch 3
... is the aqueous ... It is a fast-acting, ... gram-positive and gram-negative bacteria ... as well as most ...
... the one-step prep solution, allows the user ... applies and dries in less than 2-minutes. ... commonly used in surgical scrubbing and healthcare ... added to help provide a tacky surface ...
... designed for individual application and are ideal ... nursing homes, home healthcare settings, blood banks, ... departments. This unit dose pouch contains hydrogen ... and cleansing agent. Hydrogen Peroxide's chief value ...
... This multi-purpose topical solution ... Povidone Iodine Prep Spray is ... the possibility of cross contamination. ... an alternate method to the ...
Medicine Products: