Navigation Links
The Framingham Heart Study -- global impact, ongoing influence
Date:7/6/2010

Philadelphia, PA, July 6, 2010 Few medical investigations have had the impact of the Framingham Heart Study. This study, started in 1948, was designed as a cohort, observational study of cardiovascular disease, then recognized as a growing health threat but now has emerged as much more. The Framingham Heart study came to revolutionize thinking about cardiovascular disease, change the study of epidemiology, and even force the biostatistics community to develop multivariate analysis. In a special issue of Progress in Cardiovascular Diseases, leaders from around the world offer their views on the global impact of the Framingham Heart Study.

The issue includes 10 articles describing not only the historical background of the Framingham Study, but also some of the current public health programs around the world that grew out of Framingham. An interview with Dr. William Kannel, one of the principal investigators, provides a personal perspective on this monumental work.

From the insights developed over the 60+ years of this still-ongoing study, significant investigations show the continuing influence of Framingham. Dr. Pekka Puska describes the Finnish-North Karelia project, the most potent demonstration that behavioral alteration in lifestyle risk factors leads to improved cardiovascular outcomes. Dr. K. Srinath Reddy describes a wide-reaching public health initiative to combat an explosive emergence of cardiovascular disease in India and Southeast Asia. In another program based on the legacy of Framingham, Drs. Cother Hajat and Oliver Harrison describe their comprehensive survey of over 95% of the Abu Dhabi population to develop a nation-wide prevention program for both the native citizens and the immigrant communities.

"The now well-established risk factor concept, fundamental to prevention of CVD, originated from the Framingham study," commented Shanthi Mendis, MD, of the World Health Organization. "It generated seminal findings such as the effects of tobacco use, unhealthy diet, physical inactivity, obesity, raised blood cholesterol, raised blood pressure, and diabetes on CVD. When these findings were first published, these were novel cardiovascular risk factors, now they are the major focus for global and national prevention efforts for reducing the burden of CVD and other major noncommunicable diseases. The Framingham Heart Study has also been in the forefront of the development of cardiovascular risk prediction equations for assessment of absolute risk."

The true global impact of the Framingham Heart Study, according to Henry Greenberg, MD, St. Luke's Roosevelt Hospital Center, New York, NY, and Editor-in-Chief of Progress in Cardiovascular Diseases, is whether prevention works. "The final verdict on the efficacy and relevance of the Framingham Heart Study is the outcome. Altering behavioral or cultural or political determinants of risk does reduce the societal burden of CVD. In the United States, though lacking a top-down approach to public health, the dramatic fall in CVD mortality in the early 1960s when little but blood pressure control was available speaks to this. During the ensuing 40 years, about half of the 50% fall in CVD mortality is attributable to prevention and risk factor modification, the legacy of the Framingham Heart Study."


'/>"/>

Contact: Katrina Saling
k.saling@elsevier.com
215-239-3712
Elsevier Health Sciences
Source:Eurekalert

Related medicine news :

1. Framingham Public School District Selects Aerohive for its Next Generation Wireless Network
2. New research identifies modifiable risk factors for heart disease
3. Magnetic field measurements of the human heart at room temperature
4. Summit Medical Group hosts “Go Red Day” to Raise Awareness of Heart Disease and Stroke
5. Top 10 Ways to Avoid a Heart Attack This Super Bowl
6. Blood Thinner Combos Risky for Heart Attack Patients
7. HeartMath Offers Free Certificates that Celebrate Love and the Heart
8. Texas Health Dallas Launches Screening Program for Female Heart Disease
9. NHLBI funds preclinical tests on devices for infants and children with congenital heart defects
10. Surgery on beating heart thanks to robotic helping hand
11. Renowned Cardiologist Offers Heart Healthy Tips for the Holiday Season
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... December 07, 2016 , ... Levels of a protein in the blood associated ... appearing online in the journal Radiology. , Heart disease and brain disease exact a ... the rapidly aging population. Damage to both organs often occurs at a subclinical stage, ...
(Date:12/7/2016)... ... December 07, 2016 , ... ODU, a worldwide ... US market its advanced highly customizable contact technology solutions. , ODU Single Contact ... technologies are ideal for a wide range of applications that require customization from ...
(Date:12/7/2016)... , ... December 07, 2016 , ... ... and financial planning services to families and business owners in the greater Dallas ... behalf of the Dallas Fallen Officer Foundation. , Established in 2009 by active ...
(Date:12/7/2016)... ... December 07, 2016 , ... A. Kevin Spann Insurance, ... families throughout the Five Boroughs, is launching a charity drive to raise funds that ... the traditions and spirit of marines and Navy FMF Corpsmen. Working closely with the ...
(Date:12/7/2016)... ... December 07, 2016 , ... The Honolulu cosmetic ... redesigned website, which launched October 17, 2016, features comprehensive information regarding a wide ... layout. Visitors and patients can discover the latest clinical dermatology treatments for medical ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... Inc. (NASDAQ: IONS ), the leader in antisense therapeutics, ... BMO Capital Markets Prescriptions for Success Healthcare Conference on Wednesday, December ... A live webcast of the presentation will be available on the ... be available within 48 hours and will be archived for a ... , , ...
(Date:12/7/2016)... Inc. (NYSE: LCI ) today announced that the company ... Healthcare Conference on December 14, 2016 at 9:20 a.m. (ET) at ... . In addition, the company will host one-on-one meetings ... Annual Boston Healthcare Conference taking place on December 13, 2016 at ... , ...
(Date:12/6/2016)... 2016  Alopexx Oncology, LLC announced data from a ... protein (immunocytokine) composed of interleukin-2 and a CD20-targeting monoclonal ... B cells as Rituxan and maintains the activities of ... involved in tumor targeting, engagement of the immune system, ... of the study (abstract #95954) were presented at the ...
Breaking Medicine Technology: