Navigation Links
The ABCs of childhood z's: Snoring may be chronic despite surgery
Date:3/14/2008

Children who gain weight rapidly after having their tonsils and adenoids removed to treat sleep-disordered breathing (SDB) may improve in the short-term, but over time they may relapse or even worsen. African-American children also tend to relapse, according to new research from Cincinnati Childrens Hospital Medical Center.

Adenotonsillectomy is the most commonly performed surgery in children, ranging from about 19 per 10,000 in Canada to 115 per 10,000 in the Netherlands. In the U.S., the rate is about 50 per 10,000. It is the first line of treatment for SDB in children. For many kids, undergoing this major surgery provides only temporary relief.

The high rate of recurrence we observed in both obese and non-obese children indicates that SDB is a chronic condition, said Raouf Amin, M.D., director of pulmonary medicine at the hospital.

The results were published in the second issue for March of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

The researchers recruited 40 healthy children between seven and 13 whose parents and otolaryngologists had jointly agreed upon adenotonsillectomy surgery to treat nightly snoring. The investigators also recruited 30 sex- and age-matched children who were not undergoing adenotonsillectomy as a control group. They performed polysomnographies on each child at time of recruitment, and again at six weeks, six months, and a year following surgery. Children in the control group had polysomnographies at the same intervals.

While the majority of children with SDB showed significant improvement in their AHI scores six weeks after surgery, the rate of relapse one year later had no correlation with the six-week score. Children who relapsed were more likely to be more obese, have worse SDB at baseline, have an accelerated body mass index (BMI) gain, and to be African-American.

Most post-adenotonsillectomy outcome studies have focused on the assessment of SDB six to 16 weeks after surgery. Resolution of SDB during this window was usually interpreted as a cure for the disorder, noted Dr. Amin. We report[ed] for the first time the longitudinal outcome of adenotonsillectomy in healthy children, the important influence of BMI gain velocity and African-American race on recurrence of SDB.

Half of the non-obese children, and two-thirds of the obese children had an AHI score of greater than 3 prior to surgery. A year later, 27 percent of the non-obese children and 79 percent of obese children had AHI score of greater than 3, indicating that the surgery was significantly more effective at a year in non-obese children.

While children who were obese at the baseline were more likely to relapse than their no-obese peers, accelerated BMI gain was also an independent risk factor for relapse.

These results highlight the differential disease mechanisms between those due to obesity and those due to the rapid change in body composition associated with accelerated BMI gain, explained Dr. Amin.

Furthermore, children who relapsed had significantly higher blood pressure at follow up than children who didnt.

SDB appears to be a chronic disorder that is clearly linked to other medical problems. Given the rate of relapse, we advocate long-term follow up of children with SDB, monitoring of BMI gain, and reevaluation of children who demonstrate rapid BMI gain, especially those who are African-American, the researchers concluded.


'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. Continuous Doctor Care Key to Childhood Screenings
2. UF researchers warn parents about dangers of childhood foot burns
3. Southern California Parents and Kids Take Healthy Steps in Tackling Childhood Obesity
4. In Early Childhood, Continuous Care by One Doctor Improves Delivery of Health Screenings
5. In early childhood, continuous care by 1 doctor improves delivery of health screenings
6. Business Leaders, Policy Makers and Advocates Gather to Discuss Strategies for Securing the Nations Economy by Investing in Early Childhood
7. AAPD Announces Partnership With Head Start to Address Childhood Epidemic
8. Families Rejoice in CDCs Advisory Committee on Immunization Practices Vote for Universal Childhood Influenza Vaccination
9. Otho S.A. Sprague Memorial Institute awards Rush $230,000 for childhood obesity prevention
10. Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia
11. Childhood Influenza Immunization Coalition Responds to Recent Influenza Outbreaks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Creek, Michigan (PRWEB) , ... June 26, 2016 , ... ... joined as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in ... in honor of the city’s history as home to some of the world’s leading ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... ... fertility once they have been diagnosed with endometriosis. These women need a treatment ... also require a comprehensive approach that can help for preservation of fertility and ...
(Date:6/25/2016)... ... ... "With 30 hand-drawn hand gesture animations, FCPX users can easily customize each ... Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures into hand ... select a ProHand generator and drag it above media or text in the Final ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort to ... treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain management ... (SCD) is a disorder of the red blood cells, which can cause episodes of ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
(Date:6/23/2016)... , June 23, 2016 Research ... Pharma News Issue 52" report to their offering. ... in influenza treatment creates a favourable commercial environment for MedImmune ... growing patient base that will serve to drive considerable growth ... vaccine would serve to cap sales considerably, but development is ...
(Date:6/23/2016)... PARK RIDGE, Ill. and INDIANAPOLIS ... caliber of students receiving a Lilly Diabetes Tomorrow,s Leaders ... hands. The 2016 scholarship winners, announced today online at ... refused to let type 1 diabetes stand in the ... Lilly Diabetes has supported the Foundation,s scholarship program since ...
Breaking Medicine Technology: