Navigation Links
Tests showing smokers their individual risk of future disease will help them quit, says paper
Date:2/4/2010

Auckland, New Zealand and Chicago, USA -- February 4, 2010 -- Giving smokers information about their own individual risk of serious illness helps motivate them to quit smoking, according to a paper published in the current issue of Postgraduate Medical Journal.

"Personalized risk assessment has been the mainstay of coronary artery disease prevention and has resulted in significant mortality reduction over the last decade," said Dr. Robert Young, lead author of the article. "Such an approach could be equally applied to smoking cessation, now that we have predictive risk assessment tools that identify those at greatest risk of lung-related illness from smoking."

Though about half of long-term smokers die from smoking-related disease, and 50% of those deaths will come from lung cancer or chronic lung disease, many smokers believe they will be the ones who will escape unharmed; they carry on smoking or they try but fail to quit.

The PMJ article endorses a new model for smoking cessation to help doctors engage smokers more effectively by using what it calls 'motivational tension' anxiety based on a smoker's perception of harms versus benefits. Health concerns are an important factor in motivating smokers to quit; smoking cessation rates appear to be greatest where smokers have suffered, or been shown to be personally at risk of, life threatening complications from their smoking.

In this setting, risk assessment tools that identify those at greatest risk, such as spirometry (a puff test to measure lung function) and genetic susceptibility testing, appear to help engage smokers and improve their smoking cessation rates. When smokers see their individual risk as a result of lung function or genetic tests, that new personalised information is likely to trigger a quit attempt, and will make that quit attempt more likely to succeed. This is very similar to cholesterol and blood pressure testing in the context of cardiovascular risk assessment and treatment.

According to studies cited in the article, genetic testing for smoking-related disease demonstrated utility for all smokers and found no evidence of fatalism in higher risk people or reduced motivation for those at lower risk levels.

Smokers' attitudes about whether to carry on smoking are based on how they balance the perceived "benefits" against their understanding about the harm it causes, and their individual vulnerability to this harm, according to studies cited in the PMJ article. The "Editor's Choice" paper says even relatively small triggers can change this balance, prompting a quit attempt.

Currently, the smoking quit rate remains discouragingly low. Smokers try to quit on average 12 to 14 times before they succeed, and only about 5% of cold-turkey tries work. Every year about 41% of smokers try to quit but only 10% succeed. Drugs and nicotine replacement help, but still achieve one-year quit rates of only up to 30%.

The paper says recent research shows says smoking cessation 'interventions' by doctors that give both a trigger for action and also provide support such as medication or anti-smoking counselling may be the most effective way to help smokers quit.

A similar approach works for coronary artery disease, where cholesterol testing to personalise an individual's risk helps give doctors a way to encourage patients to make lifestyle changes or take medications. "The recent reduction in coronary artery disease mortality has, in part, been attributed to this approach," the paper says.

For smokers, both spirometry and genetic testing appear to improve quit rates, it says.

Dr Young, an Associate Professor in the Schools of Biological Sciences and Medicine at the University of Auckland in New Zealand, has led the research program underpinning a test called Respiragene which combines genetic and non-genetic factors to show smokers and ex-smokers their own risk of lung cancer, still the leading cancer killer in most developed countries, including the United States. Preliminary studies show that over 50% of smokers taking the Respiragene test take positive steps such as quitting, reducing their cigarette intake or setting a quit date. Further studies are planned to assess smoker's actions after taking the test.


'/>"/>

Contact: Ken Li
media@respiragene.com
312-532-4675
Chempetitive Group
Source:Eurekalert

Related medicine news :

1. NHLBI funds preclinical tests on devices for infants and children with congenital heart defects
2. Seattle-based PhenoPath Laboratories Retests Nearly 3,000 Breast Cancer Specimens from Quebec Breast Cancer Inquiry
3. New Tests Confirm Wood Pallets Harbor Deadly Food Poisoning Bacteria
4. Stem Cells Turned Into AIDS Killers in Lab Tests
5. Targeted Testing Receives Favorable Reviews On PADDS, Begins Nationwide Research Study On The Target Tests of Executive Functioning-OV
6. Medical Tests Hit Heart Patients With High Doses of Radiation
7. Families Could Benefit From Gene Tests in Sudden Cardiac Death Victims
8. American Heart Association Late Breaking Clinical Trial Report: Tests Predict Which Patients Are Resistant to Anti-Clotting Therapy During Angioplasty, Stenting
9. Approved lymphoma drug shows promise in early tests against bone cancer
10. $36 Billion Charged for Blood Tests and Transfusions for U.S. Premature Infant Market
11. Consumer Reports: Tests Find Wide Range of Bisphenol A in Canned Soups, Juice, and More
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2017)... ... 2017 , ... MEDsys Software Solutions, the leading provider of ... Home Care Agencies, has been awarded CIO Applications Magazine’s Top 25 Workflow Solution ... 1,000 agencies and multiple State Medicaid and Managed Care Programs. MEDsys has ...
(Date:7/27/2017)... (PRWEB) , ... July 27, 2017 , ... ... outsourced services, announces the internal promotion of Elrene Clinkscales to Vice President of ... Claims & Remittance Management, reporting to Derek Morkel, chief executive officer (CEO). , ...
(Date:7/27/2017)... ... 2017 , ... Healthy eating isn’t always easy. Currently, more than 80 percent of Americans fail ... overeat refined grains and sugar. This trend may help explain why the obesity rate seems ... obese. , As a culture, we seem to have food on the brain more. "We ...
(Date:7/27/2017)... ... July 27, 2017 , ... The Freedom from Cancer Startup ... around 117 breakthrough inventions from 55 institutions, including the National Institutes of Health ... Biomedical Imaging and Bioengineering), the United States Army, and more than fifty American ...
(Date:7/27/2017)... ... , ... Cremations recently surpassed traditional burials for the first time in the ... continue with over 70% of Americans projected to choose cremation by 2030. , In ... families to celebrate the life of a lost loved one in different ways using ...
Breaking Medicine News(10 mins):
(Date:7/20/2017)... Minn. , July 20, 2017  Prime Therapeutics LLC ... Jonathan Gavras , M.D., following today,s Institute for Clinical and ... report on the effectiveness and value of abuse-deterrent formulations ... on the policy roundtable at the meeting. ... not a material cost benefit to the use of abuse-deterrent ...
(Date:7/17/2017)... ORLANDO, Fla. , July 17, 2017  MedX ... - branded medical testing, strengthening and rehabilitation equipment, today ... Back Machine Program. MedX is considered the gold standard ... world leader in specialized medical strengthening equipment. ... into a lease with the physician or practice who ...
(Date:7/14/2017)... -- Endo International plc (NASDAQ: ENDP ) will announce ... of its senior management team will host a conference call and ... The dial-in number to access the call is ... the passcode is 45397076. Please dial in 10 minutes prior to ... A replay of the call will be available from August 8, ...
Breaking Medicine Technology: