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Testosterone Therapy May Reduce Bone Loss in Older Men
Date:4/7/2008

o small to prove or disprove the value of testosterone therapy in preventing bone loss and, perhaps, preventing osteoporosis.

"This small, short-term study indicates that men with low levels of testosterone respond to appropriate replacement as far as turnover markers indicate," said John Eisman, director of the Bone and Mineral Research Program at the Garvan Institute of Medical Research, in Sydney, Australia.

While calling the study "too small and too short to provide any insight into fracture-risk reduction or safety outcomes," Eisman said it does complement research he has done. "Our study showed that men with testosterone in the lowest quartile of the population had much higher risk of osteoporotic fractures," he said.

A large, long-term trial testing whether testosterone can prevent osteoporosis in men is needed to settle the question, Eisman said.

More information

To learn more about men and osteoporosis, visit the U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases.



SOURCES: John Eisman, Ph.D., director, Bone and Mineral Research Program, Garvan Institute of Medical Research, and professor of medicine, the University of New South Wales, Sydney, Australia; April 7, 2008, presentation, Experimental Biology 2008 conference, San Diego


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