Navigation Links
Testosterone Patch Restores Libido in Postmenopausal Women
Date:11/5/2008

But, the male hormone therapy may cause unwanted hair growth, study finds,,

WEDNESDAY, Nov. 5 (HealthDay News) -- There aren't a lot of treatment options for older women with flagging libidos, but a new study suggests that a testosterone patch may significantly improve the number of satisfying sexual episodes that women experience.

However, the increased sexual satisfaction doesn't come without side effects, such as unwanted hair. Of more concern is a possible increase in the risk of breast cancer in women taking the male hormone, although the study's authors think this finding was probably a chance occurrence.

"This is the first study to show that when used alone, testosterone administered by a skin patch significantly improves sexual well-being in postmenopausal women," said the study's lead author, Dr. Susan R. Davis, a professor of women's health at Monash University in Australia.

Results of the study were published in the Nov. 6 issue of the New England Journal of Medicine. The study was funded with research grants from Procter & Gamble Pharmaceuticals, the manufacturer of the testosterone patch, Intrinsa.

The testosterone patch is available in Europe to treat a loss of sexual desire in women, but the U.S. Food and Drug Administration turned down the manufacturer's request for approval in December 2004, citing a lack of long-term safety data, the study authors said.

The new study ran for 52 weeks -- 24 weeks were designed to test effectiveness, and the entire study period was designed to assess safety.

Just over 800 postmenopausal women who weren't taking estrogen therapy were included in the study. All of the women reported low sexual desire. The women were randomly assigned to one of three groups: treatment with a patch that delivered 300 micrograms of testosterone daily, treatment with a patch that delivered 150 micrograms of testosterone daily, or a placebo patch.

After 24 weeks, women in the 300 microgram group reported an average of 2.1 satisfying sexual episodes during a four-week period, compared to 1.2 sexually satisfying episodes for those on the lower dose, and just 0.7 satisfying episodes for women on the placebo.

Both doses of testosterone were associated with an increase in sexual desire, according to the study.

The most significant side effect was unwanted hair growth, but Davis said that most women didn't find it troubling enough to stop taking testosterone.

Four women taking testosterone were diagnosed with breast cancer during the study period; there were no cases among women on a placebo. However, Davis explained that two women probably had their cancers prior to the start of the study, while another had a high risk of the disease.

"We have carefully considered this, and we believe the likelihood is that this is a chance finding," Davis said.

Dr. Steven Goldstein, an obstetrician and gynecologist at the New York University Langone Medical Center in New York City, called the new study "helpful."

"It shows that in the double-blind, placebo-controlled trial, testosterone does have a positive effect on the frequency of satisfying sexual experiences. But, what about long-term effects?" he asked. "You have to wear this patch all the time. That means you're subjecting yourself to a hormone 24/7," he added.

Plus, Goldstein said, he'd like older people to realize that "decreased desire is not a disease," and it doesn't mean you don't love your spouse any more. There are evolutionary reasons why you don't feel the same way you did when you were 20, he explained. But, he added, if the loss of libido bothers you or is causing you distress, you should talk with your doctor about it.

Davis believes the testosterone patch should be more widely available. "I believe women have as much right as men to have a choice of therapy if sexual well-being impairs their quality of life," she said, adding, "I think [the testosterone patch] should be made available, because it is both effective and safe."

More information

To read more about aging and sexuality, visit the U.S. National Institute on Aging.



SOURCES: Susan Davis, M.D., Ph.D., professor of women's health, Monash University, Prahran, Australia; Steven Goldstein, M.D., obstetrician/gynecologist, New York University Langone Medical Center, and professor, New York University School of Medicine, New York City; Nov. 6, 2008, New England Journal of Medicine


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. 1 in 4 Men Over 30 Has Low Testosterone
2. The latest about male infertility and testosterone from NewYork-Presbyterian/Weill Cornell
3. Low Testosterone Might Shorten Mens Lives
4. Testosterone supplementation for older men appears to have limited benefit
5. MSU research indicates testosterone could guard against eating disorders
6. Older Men With Low Testosterone Face Greater Depression Risk
7. AUDIO from Medialink and Solvay Pharmaceuticals: Men with Type 2 Diabetes at Increased Risk for Low Testosterone Should Talk to Their Doctors
8. Testosterone Therapy May Reduce Bone Loss in Older Men
9. Testosterone Levels Among Financial Traders Affect Performance
10. Testosterone Spray Improves Sexual Satisfaction in Women
11. Many men with low testosterone levels do not receive treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... , ... First Choice Emergency Room , the largest network of independent ... Director of its new Mesquite-Samuell Farm facility. , “We are pleased to announce ... Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of ... of the latter, setting the bar too high can result in disappointment, perhaps even ... progress toward their goal. , Research from PsychTests.com reveals that behind ...
(Date:6/24/2016)... ... ... was in a crisis. Her son James, eight, was out of control. Prone to extreme ... “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was ... other children and say he was going to kill them. If we were driving ...
(Date:6/24/2016)... ... ... Comfort Keepers® of San Diego, CA is excited to announce they are ... drive cancer patients to and from their cancer treatments. Comfort Keepers provides quality ... and ongoing independence. Getting to and from medical treatments is one of the ...
(Date:6/24/2016)... ... 24, 2016 , ... The Haute Beauty Network, affiliated with ... as a prominent plastic surgeon and the network’s newest partner. , Dr. ... handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands by ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... N.J. , June 24, 2016  Collagen ... the design, development and manufacturing of collagen and ... regeneration announced today that Bill Messer ... and Marketing to further leverage the growing portfolio ... medical devices. Bill joins the Collagen ...
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
(Date:6/24/2016)... Research and Markets has announced the addition of the ... to their offering. ... World Market for Companion Diagnostics covers the world market for ... report includes the following: , World IVD ... (N. America, EU, ROW), 2015-2020 , World IVD Companion ...
Breaking Medicine Technology: