Navigation Links
Test for hormones in blood not reflective of hormones in breast tissue; breast cancer risk
Date:4/22/2009

Denver, Colo. Many studies determine hormone levels in the blood as a marker of breast cancer risk. But it hasn't been known whether these blood tests reflect what is happening in the breast tissue, where certain hormones fuel cancer. Researchers at Georgetown University Medical Center's (GUMC) Lombardi Comprehensive Cancer Center found that measuring the levels of four hormones in blood known to be linked to breast cancer doesn't necessarily reflect the levels of these hormones in the breast tissue itself.

In fact, the scientists say that blood tests used in research studies that measure these hormones could give a false impression of both the real breast cancer risk women face, and an imprecise picture of how these hormones affect breast cancer development. The findings are being presented at the Annual Meeting of the American Association for Cancer Research.

"We know from this study that measuring the hormones in a patient's blood is not sufficient but that is how many research studies looking at breast cancer risk are being conducted," says the study's lead author, Adana Llanos, a graduate student in genetics at GUMC. "Understanding how cancers develop in breast tissue is the key to prevention, and we need to understand how these hormones affect breast tissue."

The research team, led by Llanos and under the guidance of senior investigator, Peter G. Shields, MD, head of Lombardi's Cancer Genetics and Epidemiology Program, did something that has not been done before: They tested normal breast tissue for the levels of IGF-1, IGFBP-3, adiponectin, and leptin. High levels of IGF-1 has been linked to breast cancer development, while low levels of IGFBP-3 is linked to increased risk. High levels of adiponectin and leptin are both related to obesity, which is, in itself, a risk factor for breast cancer.

"By understanding these hormones in the normal breast environment, we will have some insight into how early changes in th
'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Organic Left Standing as the Gold Standard for Consumers Looking to Avoid Food Produced With Synthetic Growth Hormones
2. Hormones May Help Shield Women from Parkinsons
3. Findings raise new questions about evolution of hormones in mammals
4. Female Hormones Deter Salt-Sensitive Hypertension
5. Tweaking Hormones Might Ease Chronic Stress
6. Newly Released Book by Retired Scientist Links Self-Control of Hormones to Perfecting One's Life
7. Erika Schwartz MD Congratulates Oprah Winfrey for Spotlighting Bioidentical Hormones
8. Susan Lark, MD Continues to Urge Women to Fight for Their Right to Use Bioidentical Hormones
9. Susan Lark, MD Urges Women to Fight for Their Right to Use Bioidentical Hormones
10. Women Using Compounded Bioidentical Hormones Miss the Full Story About These Drugs
11. Vigorous Treadmill Workout Curbs Appetite Hormones
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... OH (PRWEB) April 27, 2015 Douglas ... to help his clients feel secure, but also helps secure ... to 7 p.m., Douglas will be manning a booth at ... Center, Lausche Building, 717 E. 17th Ave., Columbus, Ohio. ... worthy event that will feature hundreds of adoptable pets from ...
(Date:4/27/2015)... Ticket Down is a reputable source ... Valley Music Theatre and the Isleta Amphitheater. ... Mexico area can celebrate because their favorite performer will ... Buffett will be performing alongside legendary performers, Huey Lewis ... during the summer and fall months of 2015 are ...
(Date:4/27/2015)... 2015 The global coagulation analyzers ... CAGR in developed countries; however, it is expected ... as China, India and Brazil in the next ... is driven by factors such as increasing adoption ... of high-throughput hemostasis analyzers, developments in high-sensitivity point-of-care ...
(Date:4/27/2015)... 2015 Volpara Solutions today announced ... the Society of Breast Imaging’s SBI/ACR Breast Imaging ... Booth #214). VolparaDensity, the first breast density ... breast tomosynthesis datasets from multiple manufacturers, is already ... and worldwide. , The latest version ...
(Date:4/27/2015)... Puroast Coffee has signed on to sponsor the ... BattleFrog OCR is a series of rigorous courses designed by ... the training that Seals undergo, as well as provide a ... to sponsor the BattleFrog events this year,” says Puroast CEO ... well-suited to give people throughout the country the chance to ...
Breaking Medicine News(10 mins):Health News:Farmers Insurance Agent Douglas Fitzpatrick Ensures Pets Find Homes 2Health News:Cheap Jimmy Buffett Tickets at Alpine Valley Music Theatre in Elkhorn, WI and at Isleta Amphitheater in Albuquerque, NM Now on Sale at TicketDown.com 2Health News:Coagulation Analyzers Market Concluded to Reach $3.58 billion by 2019 2Health News:Coagulation Analyzers Market Concluded to Reach $3.58 billion by 2019 3Health News:Volpara Solutions Releases VolparaDensity 3.1 for Use with Tomosynthesis Systems from Multiple Manufacturers at SBI 2Health News:Volpara Solutions Releases VolparaDensity 3.1 for Use with Tomosynthesis Systems from Multiple Manufacturers at SBI 3Health News:Puroast Coffee on Tour with BattleFrog 2
... Reporter , MONDAY, April 18 (HealthDay News) -- New ... stay clear of AIDS longer if they start drug ... However, starting treatment earlier, compared to waiting, didn,t ... benefit in terms of preventing death" by prescribing the ...
... , MONDAY, April 18 (HealthDay News) -- Patients with ... die after surgery, even after non-emergency procedures, a new study ... be used to revive someone who is clinically unresponsive and ... 18 and in the August print issue of the journal ...
... New research finds that older diabetics with better control of ... as heart attacks, amputation and kidney disease. However, ... sugar levels face a slightly higher chance of dying than ... normal range. Researchers tracked more than 70,000 people with ...
... , MONDAY, April 18 (HealthDay News) -- Infection with ... many college students -- and little exposure to sunlight may ... a new study suggests. "MS is more common at ... researcher, Dr. George C. Ebers, of the University of Oxford ...
... ovarian cancer (HGSOC), the fifth-deadliest cancer among American women, ... fallopian tube malignancy masquerading as an ovarian one. While ... tubes has so far been only circumstantial, a new ... connection, a finding that could aid in the development ...
... Ill. Nearly 800 dental sleep medicine professionals from ... Meeting of the American Academy of Dental Sleep Medicine ... at the Hilton Minneapolis in Minneapolis, Minn. The meeting ... 25th Anniversary Meeting of the Associated Professional Sleep Societies. ...
Cached Medicine News:Health News:Starting HIV Drugs Earlier May Delay AIDS But Not Death 2Health News:Starting HIV Drugs Earlier May Delay AIDS But Not Death 3Health News:People With DNR Orders More Apt to Die After Any Surgery 2Health News:Low Glucose Levels May Raise Death Risk Among Older People 2Health News:Can Common Virus, Lack of Sunlight Boost MS Risk? 2Health News:New scientific model tracks form of ovarian cancer to origins in fallopian tube 2Health News:New scientific model tracks form of ovarian cancer to origins in fallopian tube 3
(Date:4/27/2015)... , April 27, 2015   AMC Health ... will showcase advances in monitored care that are transforming ... ATA 2015 Conference, May 2-5 at the ... AMC Health will share information about how their ... to help transform and personalize healthcare delivery at Booth ...
(Date:4/27/2015)... -- The North America ... $4,211.2 million by 2019, at a CAGR of 5.0% from ... the North America ophthalmology surgery device ... It also provides a glimpse of the segmentation of this ... tables and figures. http://www.micromarketmonitor.com/market/north-america-ophthalmology-surgery-devices-9102894245.html ...
(Date:4/27/2015)... 27, 2015 PAML announced today that ... with Axela, Inc. to develop multiplex assays focused ... one of the nation,s leading medical reference laboratories, ... protein analysis for clinical diagnostics. ... and assay development serves as the foundation for ...
Breaking Medicine Technology:AMC Health to Showcase Advances in Monitored Care at ATA 2015 2AMC Health to Showcase Advances in Monitored Care at ATA 2015 3AMC Health to Showcase Advances in Monitored Care at ATA 2015 4North America Ophthalmology Surgery Device Market is Expected to Reach $4,211.2 Million by 2019, at a CAGR of 5.0% From 2014 to 2019 2North America Ophthalmology Surgery Device Market is Expected to Reach $4,211.2 Million by 2019, at a CAGR of 5.0% From 2014 to 2019 3PAML and Axela Collaborate on Immune Status for Vaccine Preventable Diseases 2
... SAN DIEGO, Nov. 2, 2011 Amylin Pharmaceuticals, Inc. (Nasdaq: ... Suisse 2011 Healthcare Conference in Phoenix on Wednesday, November 9, ... M. Bradbury, president and chief executive officer, Amylin Pharmaceuticals, will ... webcast live through the "Investors" section of Amylin,s corporate website ...
... Inc. (NASDAQ: IPHS ), the leading North ... beverage, pharmaceutical, oral care and industrial end markets, today ... and completed the acquisition of Kelatron Corporation. ... manufacturer of bioactive mineral nutrients. For over 30 years, ...
Cached Medicine Technology:Innophos Holdings, Inc. Announces Acquisition of Kelatron Corporation 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: