Navigation Links
Test Might Predict Risk of Lung Cancer's Return

By Randy Dotinga
HealthDay Reporter

THURSDAY, Jan. 26 (HealthDay News) -- A new industry-funded study suggests that a molecular test can provide insight into whether patients are at high risk of a relapse after surgical treatment for a form of lung cancer.

The test, which is currently available, could help doctors decide whether the patients should undergo chemotherapy to prevent the cancer from returning.

There are caveats: The test is expensive, and researchers don't yet know whether patients determined to be at high risk will live longer if they undergo chemotherapy.

Still, "this may be one of the very first examples of where we understood enough about the molecular biology of a cancer to truly personalize the treatment of patients and actually improve the cure rate for that cancer," said study co-author Dr. Michael Mann, an associate professor of surgery at the University of California, San Francisco.

At issue is non-small-cell lung cancer, by far the most common kind of lung cancer. Even if tumors are diagnosed early and removed, the cancer will spread and kill 35 percent to 50 percent of patients.

In these cases, "even when the tumor is small and they got it all, microscopic disease has spread around the body," said Dr. John Minna, co-author of a commentary accompanying the study. He is a cancer researcher and professor of medicine at the University of Texas Southwestern Medical Center in Dallas.

Scientists are trying to find a way to predict what will happen to patients after surgery so they can figure out if chemotherapy treatment is a good idea.

In the new study, researchers gave the molecular test to 433 lung cancer patients in California and 1,006 patients in China. The researchers found that the test helped them to predict the likelihood that patients would survive for five years.

Conceivably, physicians could adjust the treatment of patients after surgery to coincide with the risk of a recurrence of their cancer. For now, though, that's not proven. The research "doesn't tell you that if you had a bad prognosis and you were treated with chemotherapy, then you'd do better," Minna said.

Still, information about the risks faced by a patient could help doctors make choices about treatments, said Minna, who called the test "promising."

Study co-author Mann agreed: "There may be an important conversation that you can have with your oncologist about potential benefit from additional therapy to reduce the likelihood of the cancer coming back."

Mann said the test -- which is currently available -- could cost several thousand dollars. Minna, the commentary co-author, said any cost over a few hundred dollars could be an issue for insurors.

The research was funded by the firm that developed the molecular test, and several of the study authors serve as consultants to the firm.

The study appears in the Jan. 27 online issue of The Lancet.

More information

For more about lung cancer, try the U.S. National Library of Medicine.

SOURCES: Michael J. Mann, M.D., associate professor, surgery, University of California, San Francisco; John D. Minna, M.D., professor, medicine, University of Texas Southwestern Medical Center, Dallas; Jan. 27, 2012, The Lancet

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Herpes Drug Might Also Slow HIV Progression
2. Bonding Hormone Might Help Some With Autism
3. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
4. Bilingualism Might Begin in the Womb
5. Teens Might Exercise More If They Think Its Fun
6. Gas Cooking Might Up Your Cancer Risk
7. Afternoon Nap Might Make You Smarter
8. What it might take to unravel the lean mean machine that is cancer
9. Increasing neurogenesis might prevent drug addiction and relapse
10. Kids Peanut Allergies Might Be Tamed: Study
11. Blood Test Might Sort Out Milk Allergies
Post Your Comments:
Related Image:
Test Might Predict Risk of Lung Cancer's Return
(Date:11/27/2015)... ... 27, 2015 , ... Lizzie’s Lice Pickers just announced a special promotion that ... of their purchase of lice treatment product. In addition, customers will receive a complimentary ... spokesperson. “Finding lice is a sure way to ruin the holidays, so we encourage ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ProSidebar: ... in Final Cut Pro X. With ProSidebar: Fasion, video editors can easily add ... ProSidebar as a minimalist title opener. Utilize presets featuring self-animating drop zones, lines, ...
(Date:11/27/2015)... ... 2015 , ... Consistent with the Radiology Business Management ... Radiology Marketing Programs meeting will showcase some of the best 2015 radiology ... Palace in Las Vegas with a pre-conference session on a collaborative approach for ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... A simply ... Jones, is an interesting show that delves into an array of issues that are ... that could benefit from open dialogue, this show is changing the subjects consumers focus ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... innovative online platform for mental health and wellness consultation, has collaborated with a ... will bridge the knowledge gap experienced by parents and bring advice from parenting ...
Breaking Medicine News(10 mins):
(Date:11/29/2015)... -- National Decision Support Company (NDSC) continues to experience ... statewide implementations. As a result, ordering providers now ... than 1 million times per month—all from within ... real-time feedback on the most appropriate imaging test ... at over 100 healthcare systems nationally, representing over ...
(Date:11/27/2015)... Une nouvelle approche consistant ... contre le cancer avancé.    --> ... au traitement photodynamique au Bremachlorin contre le cancer ... nouvelle approche consistant à combiner l,immunothérapie au traitement ...    Clinical Cancer Research . ...
(Date:11/27/2015)... 27, 2015 --> ... go online. The potential to save costs, improve treatment ... far from fully exploited as yet. Here, particular emphasis ... either via mobile tablet or directly at the patients, ... ) -->      (Photo: ...
Breaking Medicine Technology: