Navigation Links
Terry Fox Research Institute aims to change diagnosis and management of ovarian cancer worldwide
Date:10/13/2011

MONTREAL, QUE. -- Women throughout the world will benefit from a new, pan-Canadian Terry Fox Research Institute (TFRI) initiative that aims to change the way in which ovarian cancer is diagnosed and managed. TFRI and the Canadian Partnership Against Cancer are providing a total of $5-million in funding for a five-year, multi-site Ovarian Cancer Pan-Canadian Program called COEUR. The program will identify new biomarkers to predict and treat this relatively rare but deadly form of cancer, which will result in the use and application of current and new drugs more effectively for patients.

Ovarian cancer is the fifth-leading cause of cancer-related deaths in the Western world. One in every four women diagnosed with this form of cancer is resistant to standard first-line chemotherapy. Through TFRI, leading ovarian cancer researchers and clinicians across Canada have joined forces to develop a "made-in-Canada solution" to this global clinical problem facing cancer doctors.

The team's work will result in a new stratification system for ovarian carcinoma subtypes and will help clinicians better determine what treatment will work best for each patient. Patients who do not respond to standard therapy can be directed to clinical trials where new therapies are being validated.

"This project will change the way in which pathologists, physicians and clinicians think about ovarian cancer. It will help us to classify and sub-divide ovarian cancer into different diseases through molecular profiling. A better understanding of the disease will enable the development and delivery of more personalized care for the patient, which is both better and more efficacious," says TFRI President and Scientific Director Dr. Victor Ling.

"The program brings together expertise and resources from across the country to improve the lives of women in Canada and beyond who are diagnosed with ovarian cancer," says Dr. Stuart Edmonds, Director of the Research Portfolio at the Canadian Partnership Against Cancer, a national organization funded by Health Canada to lead the implementation of a co-ordinated cancer strategy. "This is one of several projects the Partnership is supporting with the practical goal of identifying emerging technologies that can improve the early detection and treatment of cancer and lead to better outcomes."

Momentum to form the consortium of 35 investigators came from within the ovarian cancer community. The project is headed up by three Canadian researchers at two prominent cancer care and research centres. At the University of Montreal Hospital Research Centre (CRCHUM*), molecular oncologist Dr. Anne-Marie Mes-Masson and gynecologist oncologist Dr. Diane Provencher are the principal investigators. Dr. David Huntsman, a genetic pathologist with the Ovarian Cancer Research Program at BC Cancer Agency and Vancouver Coastal Health, will co-lead the study from Vancouver.

"Ovarian cancer is a relatively rare disease that is also very complex. Today we know that it consists of several different subtypes; these are not yet well understood and we have significantly more work ahead to determine what treatment will work for patients and their specific tumour subtype," says Dr. Huntsman. "This program includes an important knowledge transfer component that will enable the results to be rapidly deployed within the Canadian pathology community and readily translated into practice."

"The women who are participating in this initiative by providing tissue samples for collection and analysis are hoping this research will accelerate the pace of discovery and validation of new biomarkers for ovarian cancer," says Dr. Provencher. "We hope to redirect women to new clinical trials and, in particular, those women who don't respond to first-line therapy."

"The team is building a unique, central scientific platform that will create a rich clinical resource for researchers to validate new biomarkers and treatments for ovarian cancer. By linking together laboratory scientists with the oncologists, surgeons and pathologists who work with the patients on the front lines, our work will be much more relevant and bear fruit that will reach patients much more quickly," says Dr. Mes-Masson. A strength of the program is the ability to link research results across multiple studies underway across the country.
'/>"/>

Contact: Kelly Curwin
kcurwin@tfri.ca
778-237-8158
Terry Fox Research Institute
Source:Eurekalert

Related medicine news :

1. Nevada Qui Tam Attorney Tim Terry to Address Sacramento Gold Rush Chapter of the National Contract Management Association (NCMA)
2. QHR'S Terry Peeples Named 2010 Grassroots Champion by American Hospital Association
3. Great Salt Lake Chapter of National Contract Management Association Hosts Presentation on False Claims Act by Qui Tam Attorney Tim Terry
4. East Tennessee Attorney Brack Terry Obtains $120,000 Jury Award For Injured Mail Carrier
5. Qui Tam Attorney Tim Terry to Speak at Phoenix Thunderbird Chapter of the National Contract Management Association (NCMA)
6. Motivational and Inspirational Author Dr. Terry Cole-Whittaker's New Book: "Live Your Bliss: Practices that Produce Happiness and Prosperity"
7. False Claims Act Attorney Tim Terry to Address Arizona Chapter of the Association of Certified Fraud Examiners
8. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
9. 2010 HSR Impact Award recognizes surgical safety research
10. MSU launches first anti-counterfeiting research program
11. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... New York, NY (PRWEB) , ... March 23, 2017 , ... 82% of adults are ... every 3 kids do not brush their teeth the minimum two times a day that ... teeth; with students missing 51 million hours of school and adults missing 164 million hours ...
(Date:3/23/2017)... Los Angeles, CA (PRWEB) , ... March 23, ... ... Series A funding investment in Los Angeles based healthcare technology company California Healthcom ... group’s portfolio into the US, and healthcare arena. With headquarters in California, CHG ...
(Date:3/23/2017)... ... 2017 , ... After raising more than $1.135 million ($1,479,231 AUD) from nearly ... in crowdfunding history, has established a U.S. Headquarters in New York City, FaceCradle ... , “We’re excited to be operating on U.S. shores, where most of our initial ...
(Date:3/23/2017)... ... 23, 2017 , ... According to the National Sleep Foundation , poor ... the only cause of the sunken-eye look, which can include dark circles or bags ... poor health are likely due to genetics, dehydration, allergies, and losing fat beneath the ...
(Date:3/23/2017)... ... March 23, 2017 , ... The American Board of Quality Assurance ... Anniversary of ABQAURP’s dedication to Health Care Quality and Management and Patient Safety. , ... only to the association, but also to the Health Care Quality and Patient Safety ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... VANCOUVER, British Columbia , March 23, 2017 /PRNewswire/ ... "Company" or "Sophiris"), a clinical late-stage biopharmaceutical company developing ... announced that data from its successful Phase 2a study ... treatment for localized prostate cancer, will be presented as ... nd Annual European Association of Urology in ...
(Date:3/23/2017)... 2017  Ethicon* today announced the completion of ... held medical device company that manufactures and markets ... treatment of Gastroesophageal Reflux Disease (GERD). This acquisition ... portfolio of minimally invasive options for patients suffering ... of the transaction have not been disclosed. ...
(Date:3/23/2017)... LITTLE SILVER, N.J. , March 23, 2017 ... device company, today announced that it has kicked ... in-growth into their 3D printed bone segments. ... of Engineering, "Our unique variable honeycomb lattice structures ... bone in-growth as compared to current allograft wedges ...
Breaking Medicine Technology: