Navigation Links
Tendon stimulation the key to repair in 'tennis elbow'
Date:6/11/2014

New data presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) show that ultrasound-guided injections of growth factors-containing platelet-rich plasma (PRP) are no more effective in treating recently developed epicondylitis than injections of saline.1

Lead researcher, Patrick Le Goux of the Hpitaux Universitaires Paris Ile-de-France Ouest, France, commented, "while PRP injections were shown to have no inherent benefit in the treatment of epicondylitis, what is exciting is that pain scores in both treatment groups decreased significantly over the course of the trial. The healing process is stimulated by the echo-guided injection of a substance and/or by the own effect of the needle (needling); the injections stimulate the process of tendon repair through an irritation effect, a technique known as prolotherapy."

Epicondylitis is a painful condition that occurs when the tendons in the elbow are overworked, usually by repetitive motions of the wrist and arm. In lateral epicondylitis (also referred to as tennis elbow), the pain occurs primarily where the tendons of the forearm muscles attach to the bone on the outside of the elbow2 and medial epicondylitis (also referred to as golfer's elbow) where the tendons attach to the bone on the inside of the elbow. The pain of both conditions may also spread to the forearm and wrist.3

Although a large number of treatments including physiotherapy, corticosteroid injections, and non-steroidal anti-inflammatory drugs are used to treat epicondylitis, there is no consensus on which is the most effective.4 Recently, local injections of growth factors containing platelet-rich plasma (PRP) were proposed as a new therapeutic technique for boosting tendon repair,5 with ultrasound guidance of the intra-tendinous injections used to optimise the procedure.6

In this latest study, patients with recent onset epicondylitis (pain ≤3 months), confirmed by MRI and/or ultrasound, were treated with two ultrasound-guided injections at 4 week intervals. Patients received either PRP (ACP, Arthrex) or saline solution and were monitored by an independent clinical evaluator, blinded to the treatment at baseline, one, three, six and 12 months.

The primary evaluation criterion was the relative improvement from baseline to six months in pain score (PS) on the visual analogue scale (0-10). The secondary criteria was the assessment of pain (yes/no) on isometric contraction of the second radial and of the muscle of the posterior forearm (extensor digitorum communis), the Roles-Maudsley score* (1-4), the proportion of asymptomatic patients (PS ≤1) at six and 12 months follow-up and the proportion of patients with persistent pain (PS >2) at 12 months follow-up. Fifty patients were included in the study, 25 in each arm, but only 22 in both groups completed the follow up at 12 months.

At a six-month follow-up, no statistically significant difference was found between the groups for mean relative improvement in pain (ACP 54.7% vs. control 63.6%; p=0.24) and no statistically significant difference was found for the secondary criteria. In the two groups, the pain score decreased significantly between two consecutive visits from 6.80.8 (PRP) and 71 (control) at baseline to 2.51.6 (PRP) and 2.11.6 (control) at 6 months and 1.651.5 (PRP) and 1.82.1 (control) at 12 months. At six months, 34% of all patients were asymptomatic; 66% were asymptomatic at one year. The proportion of patients with persistent pain at 12 months was 23.8% in both groups. No adverse effects were observed.


'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-078-801-73209
European League Against Rheumatism
Source:Eurekalert

Related medicine news :

1. Scientists discover new clues explaining tendon injury
2. Surgery May Not Be Needed for Ruptured Achilles Tendon
3. This is why it takes so long to get over tendon injuries
4. A New Topical Pain-Relief Product, Tendonex Hits the Shelves This Month
5. Ten Skechers Lawsuits Filed by Wright & Schulte on Behalf of Consumers Who Sustained Severe Tendon Damage Allegedly Due to Wearing Skechers Shape-Ups
6. PRP therapy improves degenerative tendon disease in athletes
7. Stem cells inside sutures could improve healing in Achilles tendon injuries
8. Deep Brain Stimulation May Offer Longer-Term Relief for Parkinsons
9. Electrical brain stimulation can alleviate swallowing disorders after stroke
10. New research confirms efficacy of transcranial magnetic stimulation for depression
11. Electrical Brain Stimulation Curbs Epileptic Seizures in Rats
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2017)... ... September 20, 2017 , ... Collins Concrete Coatings announced that ... rely on safety and cleanliness. This unique flooring system uses silver ion technology ... for centuries for its antimicrobial properties. Unlike antibiotics, which kill specific microorganisms, silver ...
(Date:9/20/2017)... ... September 20, 2017 , ... Renal Support Network’s annual essay ... kidney disease. The theme “Describe a positive decision that you have made about ... meet only one qualification— to have been diagnosed with chronic kidney disease. This ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... medical device compliance and commercialization, has just released a new white paper ... is more adamant than ever about medical device, pharmaceutical, and combination product ...
(Date:9/20/2017)... ... September 20, 2017 , ... Demand generation pioneer True ... edition of MarTech: The Marketing Tech Conference October 2–4, at the Hynes Convention ... speakers — representing such thought-leading companies as JP Morgan Chase, GE Digital, ...
(Date:9/20/2017)... ... September 20, 2017 , ... As part ... company recently unveiled a redesigned website. The new site – still located at ... owners, architects, contractors and other industry users that Garland serves. , After an ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... MOUNTAIN LAKES, N.J. , Sept. 12, 2017  Consumer reviews ... Embrace Hearing as the number one company for hearing ... Oticon™, ReSound™ and fifteen other brands. ... Embrace Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that ...
(Date:9/9/2017)... , Sept. 9, 2017  Eli Lilly and ... primary and secondary endpoint data for lasmiditan, an investigational, ... which demonstrated statistically significant improvements compared to placebo in ... highlighted today at the 18th Congress of the International ... "The data presented today demonstrate lasmiditan,s potential ...
(Date:9/7/2017)... STOCKHOLM , Sept. 7, 2017 NuvoAir ... Air Smart Spirometer, announced today a partnership with Novartis Pharma ... partnership solidifies NuvoAir,s position as the leading mobile spirometry platform ... respiratory patients. ... spirometry test ...
Breaking Medicine Technology: