Navigation Links
Tendon stimulation the key to repair in 'tennis elbow'
Date:6/11/2014

New data presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) show that ultrasound-guided injections of growth factors-containing platelet-rich plasma (PRP) are no more effective in treating recently developed epicondylitis than injections of saline.1

Lead researcher, Patrick Le Goux of the Hpitaux Universitaires Paris Ile-de-France Ouest, France, commented, "while PRP injections were shown to have no inherent benefit in the treatment of epicondylitis, what is exciting is that pain scores in both treatment groups decreased significantly over the course of the trial. The healing process is stimulated by the echo-guided injection of a substance and/or by the own effect of the needle (needling); the injections stimulate the process of tendon repair through an irritation effect, a technique known as prolotherapy."

Epicondylitis is a painful condition that occurs when the tendons in the elbow are overworked, usually by repetitive motions of the wrist and arm. In lateral epicondylitis (also referred to as tennis elbow), the pain occurs primarily where the tendons of the forearm muscles attach to the bone on the outside of the elbow2 and medial epicondylitis (also referred to as golfer's elbow) where the tendons attach to the bone on the inside of the elbow. The pain of both conditions may also spread to the forearm and wrist.3

Although a large number of treatments including physiotherapy, corticosteroid injections, and non-steroidal anti-inflammatory drugs are used to treat epicondylitis, there is no consensus on which is the most effective.4 Recently, local injections of growth factors containing platelet-rich plasma (PRP) were proposed as a new therapeutic technique for boosting tendon repair,5 with ultrasound guidance of the intra-tendinous injections used to optimise the procedure.6

In this latest study, patients with recent onset epicondylitis (pain ≤3 months), confirmed by MRI and/or ultrasound, were treated with two ultrasound-guided injections at 4 week intervals. Patients received either PRP (ACP, Arthrex) or saline solution and were monitored by an independent clinical evaluator, blinded to the treatment at baseline, one, three, six and 12 months.

The primary evaluation criterion was the relative improvement from baseline to six months in pain score (PS) on the visual analogue scale (0-10). The secondary criteria was the assessment of pain (yes/no) on isometric contraction of the second radial and of the muscle of the posterior forearm (extensor digitorum communis), the Roles-Maudsley score* (1-4), the proportion of asymptomatic patients (PS ≤1) at six and 12 months follow-up and the proportion of patients with persistent pain (PS >2) at 12 months follow-up. Fifty patients were included in the study, 25 in each arm, but only 22 in both groups completed the follow up at 12 months.

At a six-month follow-up, no statistically significant difference was found between the groups for mean relative improvement in pain (ACP 54.7% vs. control 63.6%; p=0.24) and no statistically significant difference was found for the secondary criteria. In the two groups, the pain score decreased significantly between two consecutive visits from 6.80.8 (PRP) and 71 (control) at baseline to 2.51.6 (PRP) and 2.11.6 (control) at 6 months and 1.651.5 (PRP) and 1.82.1 (control) at 12 months. At six months, 34% of all patients were asymptomatic; 66% were asymptomatic at one year. The proportion of patients with persistent pain at 12 months was 23.8% in both groups. No adverse effects were observed.


'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-078-801-73209
European League Against Rheumatism
Source:Eurekalert

Related medicine news :

1. Scientists discover new clues explaining tendon injury
2. Surgery May Not Be Needed for Ruptured Achilles Tendon
3. This is why it takes so long to get over tendon injuries
4. A New Topical Pain-Relief Product, Tendonex Hits the Shelves This Month
5. Ten Skechers Lawsuits Filed by Wright & Schulte on Behalf of Consumers Who Sustained Severe Tendon Damage Allegedly Due to Wearing Skechers Shape-Ups
6. PRP therapy improves degenerative tendon disease in athletes
7. Stem cells inside sutures could improve healing in Achilles tendon injuries
8. Deep Brain Stimulation May Offer Longer-Term Relief for Parkinsons
9. Electrical brain stimulation can alleviate swallowing disorders after stroke
10. New research confirms efficacy of transcranial magnetic stimulation for depression
11. Electrical Brain Stimulation Curbs Epileptic Seizures in Rats
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... ... , ... My T Chai, a South African company that creates a number ... RevNutrition.com, a popular website specializing in sales of nutritional products. , Chai tea ... Siam. It spread across Asia and Africa quickly, and today recipes vary from region ...
(Date:4/24/2017)... PORT RICHEY, Fla. (PRWEB) , ... April 24, ... ... Control and Prevention (CDC), rising prescription opioid overdose deaths now claim the lives ... has slashed its civil case filings against drug manufacturers, distributors, pharmacies and prescribers ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... Rod Burkett, ... Senior Housing News website. , Rod has been at the forefront of Gardant since ... culture. As CEO, Rod has overseen the opening of more than 40 new senior ...
(Date:4/24/2017)... ... April 24, 2017 , ... Come to PAINWeekEnd (PWE) Tampa ... Walter Blvd, for an educational and exciting 2-day program. , An attendee at ... this before they approach patients” about the course entitled Ain't Misbehavin': Decreasing and Managing ...
(Date:4/24/2017)... ... April 24, 2017 , ... A new global study of ... student well-being has seriously declined. "When disenfranchised youth from the heart of our ... State to turn the historic multi-ethnic and multi-religious powerhouses of the Middle East ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... - CRH Medical Corporation (TSX: CRH) (NYSE MKT: CRHM) (the "Company"), announces that ... Conference 2017 at the Sheraton Hotel in Toronto, Ontario ... of the Company is scheduled to present on Tuesday, May 2 ... the Chairman of the Board, Tony Holler will also ... For more ...
(Date:4/19/2017)... , April 19, 2017 Global Prostate ... report on the prostate cancer therapeutics market analyzes ... market. Increasing prevalence of prostate cancer, launch of ... the development of new drugs & therapeutic biological ... drug due to lesser side effects are some ...
(Date:4/19/2017)...  New research provides evidence that an old drug may ... study released today that will be presented at the ... Boston , April 22 to 28, 2017. ... disease, the oral drug levodopa has long been considered the ... the disease progresses, the effects of the medication can partially ...
Breaking Medicine Technology: