Navigation Links
Tendon complications, though rare, linked to statins
Date:2/27/2008

>

The authors note that tendon complications due to statins may be largely unreported; no cases were reported during the large therapeutic trials that included more than 30,000 patients, but this may have been due to controlling for factors that predisposed patients to tendon conditions. In this study, an increasing number of patients with complications was seen with the increasing number of prescriptions between 1990 and 2005. They also note that although the prevalence of tendon problems in connection with statins is low, all types of statins could potentially cause tendon problems, which occurred at the recommended dosages.

Our study suggests that regular tendinous clinical examination may be required in statin-treated patients, particularly during the first year following statin therapy initiation, the authors state. They also suggest that it is worth considering interrupting statin therapy before strenuous physical activity such as marathon running.

Although it is not known how statins may produce tendon injury, there are several theories. It may be that blocking cholesterol synthesis reduces the cholesterol content of tendon cell membranes, making them unstable, or that statins either reduce the levels of proteins involved in maintaining tendon cells or destroy vascular smooth muscle cells.

The authors suggest that although statins are effective, physicians should be aware that their side effects may include tendon complications. We also suggest that patients who are at risk of developing statin-associated tendon manifestations and who require statins be routinely questioned about symptoms consistent with tendon involvement, they state, adding that postmarketing surveillance appears to be a major tool for early detection of safety problems with a new drug.


'/>"/>

Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

5

GOOD

Page: 1 2

Related medicine news :

1. Achilles Tendon Surgery Advances Speed Recovery
2. Freeze-dried tendon implants prove effective in early studies
3. Saline Wash May Ease Shoulder Tendonitis
4. Ultrasound-guided injections help ease chronic Achilles tendon pain
5. USC researcher identifies stem cells in tendons that regenerate tissue in animal model
6. Testing delays cause severe AIDS complications, Einstein researchers find
7. Expressive writing appears to change thoughts and feelings about cancer
8. Home Oxygen Care Leaders Say Presidents Budget Will Lead to Significant Patient Service Disruptions, Call for Thoughtful Reforms as Opposed to Repeated Cuts
9. Thought Leaders in Morbid Obesity Treatment Convene at Upcoming Surgical Conference
10. Sickle Cell Patients in More Pain Than Thought
11. Sickle Cell Disease Pain Can Occur Daily and Is Much More Severe Than Previously Thought
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... of Michigan study challenges previous research that suggests ... The study, a collaboration between researchers at U-M ... deeper into the controversial argument over whether MLB ... pitchers of the same race. It found little ... Winfree, associate professor of sport management at the ...
(Date:5/22/2013)... -- Over the next two decades, the cost of ... more than double, topping more than $180 billion a ... driving the increase: an aging population. The report, from ... Association, was published May 22 in the journal ... care system," Dr. Bruce Ovbiagele, chairman of the department ...
(Date:5/22/2013)... researchers report that hospitals may be reaping enormous ... by preventable bloodstream infections contracted in their intensive ... reported online in the American Journal of ... ICU patient who develops an avoidable central line-associated ... to care for than a similar infection-free patient. ...
(Date:5/22/2013)... May 22, 2013 Phelps Memorial Hospital ... Westchester Lung Nodule Center for individuals who would ... cancer care. Lung cancer is the deadliest form of cancer ... in the U.S. die from lung cancer than from breast, ... cancers, early detection increases survival rates. It is well ...
(Date:5/22/2013)... 22, 2013 Hurricane preparation isn’t just ... That’s why Amica Insurance is reminding everyone ... upcoming hurricane season. , “An important part of hurricane ... a senior assistant vice president at Amica Insurance. “The ... the threat of a storm.” , Flood damage is ...
Breaking Medicine News(10 mins):Health News:U-M study challenges notion that umpires call more strikes for pitchers of same race 2Health News:Cost of Treating Strokes in U.S. Could Soar to $180B Annually by 2030: Report 2Health News:Cost of Treating Strokes in U.S. Could Soar to $180B Annually by 2030: Report 3Health News:Hospitals profit when patients develop bloodstream infections 2Health News:Hospitals profit when patients develop bloodstream infections 3Health News:Hospitals profit when patients develop bloodstream infections 4Health News:Phelps Memorial Hospital Center Establishes The Westchester Lung Nodule Center To Diagnose And Administer Lung Cancer Care 2Health News:Phelps Memorial Hospital Center Establishes The Westchester Lung Nodule Center To Diagnose And Administer Lung Cancer Care 3Health News:Reviewing Insurance Policies: a Key Part of Hurricane Preparations 2
... music industry,veteran and TV personality, is coming to ... about type 2 diabetes and its connection to,cardiovascular ... to speak on behalf of a national campaign, ... type 2 diabetes manage the disease,and reduce the ...
... ANSS ), a global innovator of simulation ... today announced it is a,sponsor of the Dinosaurs ... of,Natural History in Pittsburgh. This is the first ... immersive environments that are,composed of original fossil specimens. ...
... 17 NBTY, Inc. (NYSE:,NTY) (http://www.NBTY.com ), a ... that it will web cast the,presentation by Harvey Kamil, ... Small And Mid-Cap Conference in Las Vegas on,Wednesday, March ... web cast live on the Company Web,site, http://www.nbty.com ...
... chemokine receptor believed ... role in Crohn,s disease -, CAMBRIDGE, Mass., March 17 ... advancement of,MLN3126, a new product candidate, from the Company,s discovery ... CCR9, a,chemokine receptor known to be important in the migration ...
... Studies Now Available to the Public, ... Corporation,today announced the release of InSight(TM), a ... and sharpens the brain,s ability to process,visual ... just visual,processing abilities, but also increases driving ...
... Researchers will unveil a,new brain fitness ... in numerous,published studies to help people maintain ... of daily living tasks essential to,independence. The ... San,Francisco-based neuroscience company, will introduce the new ...
Cached Medicine News:Health News:Randy Jackson and the American Heart Association Educate Raleigh Area Residents About the Connection Between Type 2 Diabetes and Cardiovascular Disease 2Health News:Randy Jackson and the American Heart Association Educate Raleigh Area Residents About the Connection Between Type 2 Diabetes and Cardiovascular Disease 3Health News:ANSYS Sponsors Dinosaurs Exhibit at Carnegie Museum of Natural History 2Health News:ANSYS Sponsors Dinosaurs Exhibit at Carnegie Museum of Natural History 3Health News:NBTY to Web Cast Presentation at Citigroup Small and Mid-Cap Conference 2Health News:Millennium Expands IBD Franchise with Addition of New Development Candidate 2Health News:Millennium Expands IBD Franchise with Addition of New Development Candidate 3Health News:New Brain Training Program Improves Quality of Life 2Health News:New Brain Training Program Improves Quality of Life 3Health News:New Brain Fitness Training Promotes Health and Independence of Long Term Care Insurance Policyholders 2Health News:New Brain Fitness Training Promotes Health and Independence of Long Term Care Insurance Policyholders 3
(Date:5/22/2013)... YORK , May 22, 2013  The Lupus ... conference devoted to advancing new treatments for lupus nephritis, ... 60 percent of patients. The conference launched a new ... the Lupus Nephritis Trials Network (LNTN). More ... and the kidney came together to focus on two ...
(Date:5/22/2013)... May 22, 2013  Modern Medical announced today ... Launched in November 2012 in a test phase, ... to stop the rising opioid abuse in the ... program designed to protect employees, physicians and employers ... necessary balance to provide pain relief for the ...
(Date:5/22/2013)... , May 22, 2013  MGT Capital Investments, Inc. ... present at the Second Annual Marcum LLP MicroCap Conference ... York City at the Grand Hyatt Hotel.  ... Executive Officer, will update investors and answer questions. ... Company,s presentation is scheduled to begin at 9:30 a.m. ...
Breaking Medicine Technology:Lupus Research Institute Hosts First International Conference to Advance New Treatments for Lupus Nephritis 2Modern Medical Introduces Opioid Abuse Solution to the Workers' Compensation Industry 2MGT Capital Investments, Inc. To Present At The Second Annual Marcum LLP MicroCap Conference 2MGT Capital Investments, Inc. To Present At The Second Annual Marcum LLP MicroCap Conference 3MGT Capital Investments, Inc. To Present At The Second Annual Marcum LLP MicroCap Conference 4
... Kosan Biosciences,Incorporated (Nasdaq: KOSN ) today announced ... lead Hsp90 inhibitor, from a Phase,2 trial in combination ... the 2008 Annual Meeting of the American,Society of Clinical ... 31 through June 3, 2008., Abstract 1027, titled, ...
... Spain, May 13 ,Boston Scientific Corporation (NYSE: ... the SPIRIT III clinical trial, which continue ... of the market-leading TAXUS(R) Express2(TM),Paclitaxel-Eluting Coronary Stent ... clinical evidence for the XIENCE(TM) V (PROMUS(TM)),Everolimus-Eluting ...
Cached Medicine Technology:Kosan Announces Data Presentations at ASCO 2008 Annual Meeting 2Kosan Announces Data Presentations at ASCO 2008 Annual Meeting 3SPIRIT III Results Reaffirm Strong Performance of Boston Scientific PROMUS(TM) and TAXUS(R) Express(R) Stents 2SPIRIT III Results Reaffirm Strong Performance of Boston Scientific PROMUS(TM) and TAXUS(R) Express(R) Stents 3SPIRIT III Results Reaffirm Strong Performance of Boston Scientific PROMUS(TM) and TAXUS(R) Express(R) Stents 4
... EnVision Autoclavable Camera Head with an integrated coupler ... Made of a non-metallic material, it is cool ... just minutes. This product incorporates Smarthead technology allowing ... number of times the camera head has been ...
... 1-Chip Camera System provides easy-to-use features, auto ... scope. The camera head construction is based ... 14, Complete 1-Chip Camera System, International (GS ... Unit (CCU) with video cables , (GS ...
... offers 800+ lines of resolution along with color ... white balance features in a user-friendly design. , ... includes: , (GS 9923) Camera Control Unit (CCU) ... head with 3 meter cable (10 ft.)(1/2" format ...
Provides a combination of concentrated cold / hot and compression for the neck...
Medicine Products: