Navigation Links
Tender Breasts From Combo HRT Linked to Higher Cancer Risk

FRIDAY, Nov. 18 (HealthDay News) -- Women who develop breast tenderness after starting combination estrogen and progestin menopause therapy have a 33 percent higher risk of developing breast cancer than those who don't experience breast tenderness, a new study says.

It also found that new-onset breast tenderness was not associated with increased breast cancer risk among women taking estrogen alone.

The findings, based on an analysis of data from more than 16,600 women on the combination therapy and nearly 10,750 taking estrogen alone, appear in the Nov. 17 online edition of the journal Breast Cancer Research and Treatment.

"This study showed that developing new breast tenderness after the start of hormone therapy was associated with increased breast cancer risk only in women on the combination estrogen plus progestin therapy, not estrogen therapy alone," study first author Dr. Carolyn Crandall, a professor of general internal medicine and a scientist with the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, said in a UCLA news release.

However, the association between breast tenderness and increased cancer risk does not mean that there is a cause-and-effect relationship.

A study published last month by Crandall found that new-onset breast tenderness was much more pronounced in women receiving the combination therapy than in those receiving estrogen alone. The association between new-onset breast tenderness and breast-density changes was also more pronounced in women receiving the combination therapy.

"The consistent theme we've run across throughout these studies is that estrogen and progestin compared to estrogen alone have a more marked effect on breast tissue," Crandall said. "One theory is that there may be more growth of breast tissue, making the breasts more dense, when women take the combination therapy."

Higher breast density is linked with a higher risk of breast cancer.

Crandall stressed that women taking hormone therapy have only a slight risk of developing breast cancer overall.

"We don't want to incite panic, because breast cancer is rare in women taking hormone therapy, but the point is that women are terrified of getting breast cancer as a result of menopausal hormone therapy," Crandall said.

"Where I think this (new) study would be important is for women already on either combination hormone therapy or estrogen alone," Crandall added. "If they do develop breast tenderness, it would be good for them to know the results of this study and to consider discussing them with their physician."

Women on hormone therapy who develop new-onset breast tenderness should be sure to get their regular clinical breast exams and mammograms, Crandall advised.

More information

The U.S. National Institute of Child Health and Human Development has more about hormone replacement therapy.

-- Robert Preidt

SOURCE: University of California, Los Angeles, news release, Nov. 16, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Breast tenderness in women getting combo hormone therapy associated with increase in breast density
2. When Size Matters, Men Can Turn to Penile Extenders: Study
3. Noninvasive extenders are better than surgery for men who want a longer penis
4. Bartenders may have role in assisting troubled war veterans
5. Denser Breasts Raise Odds of Second Breast Cancer, Study Finds
6. Jenny McCarthy - Actress, Activist, and Model - Dedicates bforacure's ‘breasts are beautiful' to Help Raise Money for Breast Cancer Charities
7. Combo hormone therapy has increased breast cancer risk over estrogen alone
8. New drug combo targets multiple cancers
9. FDA Approves First Combo Drug for Diabetes, Cholesterol
10. Drug Combo Might Fight Aggressive Breast Cancer More Safely
11. For Some Prostate Cancer Patients, Combo Treatment Improves Survival
Post Your Comments:
Related Image:
Tender Breasts From Combo HRT Linked to Higher Cancer Risk
(Date:11/25/2015)... ... ... Dr. John Pierce, Medical Director at the Ageless Forever clinic in Las ... Pro laser therapy cap. FDA cleared for safety and efficacy, the Capillus272 offers men ... surgery, prescription pills, or topical foams. , “Capillus272™ Pro is a home-use device ...
(Date:11/25/2015)... ... 2015 , ... On November 10, 2015, Bohrer Brady, LLC filed a class ... of a home health care worker who provided companionship services for the elderly, ill ... employed by Humana, Inc., Humana at Home, Inc., and SeniorBridge Family Companies (CT), Inc. ...
(Date:11/25/2015)... ... November 25, 2015 , ... According to an article ... being more and more widely heralded as a breakthrough for performing hernia repairs. The ... over traditional laparoscopic surgery is that it can greatly reduce the pain that a ...
(Date:11/25/2015)... ... November 25, 2015 , ... Dental professionals who would like to ... are invited to attend Dr. Mark Iacobelli’s Advanced Implant Mentoring (AIM) CE course. Courses ... , As the co-founders of Advanced Implant Mentoring (AIM), Dr. Iacobelli and Dr. ...
(Date:11/25/2015)... ... November 25, 2015 , ... Wimbledon ... programs, launches new Wimbledon Athletics Facebook page to educate the public, ... unsuspected cardiac abnormalities. About 2,000 people under the age of 25 die from ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , Nov. 26, 2015 Research and ... the "Advanced Wound Care Market by Type (Dressings, ... End User (In-Patient Facility, Out-Patient Facility), and Geography - ... --> --> ... description, definition and forecast of the global advanced wound ...
(Date:11/26/2015)... 26, 2015 ... adds "Global Repaglinide Industry 2015 ... on China Repaglinide Market, 2010-2019" reports ... and information to its online business ... . --> ...
(Date:11/26/2015)... 2015 Research and Markets ( ... "2016 Future Horizons and Growth Strategies in the ... Country Segment Forecasts, Competitive Intelligence, Emerging Opportunities" ... --> --> This new 247-page ... therapeutic drug monitoring market, including emerging tests, technologies, ...
Breaking Medicine Technology: