Navigation Links
Tender Breasts From Combo HRT Linked to Higher Cancer Risk

FRIDAY, Nov. 18 (HealthDay News) -- Women who develop breast tenderness after starting combination estrogen and progestin menopause therapy have a 33 percent higher risk of developing breast cancer than those who don't experience breast tenderness, a new study says.

It also found that new-onset breast tenderness was not associated with increased breast cancer risk among women taking estrogen alone.

The findings, based on an analysis of data from more than 16,600 women on the combination therapy and nearly 10,750 taking estrogen alone, appear in the Nov. 17 online edition of the journal Breast Cancer Research and Treatment.

"This study showed that developing new breast tenderness after the start of hormone therapy was associated with increased breast cancer risk only in women on the combination estrogen plus progestin therapy, not estrogen therapy alone," study first author Dr. Carolyn Crandall, a professor of general internal medicine and a scientist with the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, said in a UCLA news release.

However, the association between breast tenderness and increased cancer risk does not mean that there is a cause-and-effect relationship.

A study published last month by Crandall found that new-onset breast tenderness was much more pronounced in women receiving the combination therapy than in those receiving estrogen alone. The association between new-onset breast tenderness and breast-density changes was also more pronounced in women receiving the combination therapy.

"The consistent theme we've run across throughout these studies is that estrogen and progestin compared to estrogen alone have a more marked effect on breast tissue," Crandall said. "One theory is that there may be more growth of breast tissue, making the breasts more dense, when women take the combination therapy."

Higher breast density is linked with a higher risk of breast cancer.

Crandall stressed that women taking hormone therapy have only a slight risk of developing breast cancer overall.

"We don't want to incite panic, because breast cancer is rare in women taking hormone therapy, but the point is that women are terrified of getting breast cancer as a result of menopausal hormone therapy," Crandall said.

"Where I think this (new) study would be important is for women already on either combination hormone therapy or estrogen alone," Crandall added. "If they do develop breast tenderness, it would be good for them to know the results of this study and to consider discussing them with their physician."

Women on hormone therapy who develop new-onset breast tenderness should be sure to get their regular clinical breast exams and mammograms, Crandall advised.

More information

The U.S. National Institute of Child Health and Human Development has more about hormone replacement therapy.

-- Robert Preidt

SOURCE: University of California, Los Angeles, news release, Nov. 16, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Breast tenderness in women getting combo hormone therapy associated with increase in breast density
2. When Size Matters, Men Can Turn to Penile Extenders: Study
3. Noninvasive extenders are better than surgery for men who want a longer penis
4. Bartenders may have role in assisting troubled war veterans
5. Denser Breasts Raise Odds of Second Breast Cancer, Study Finds
6. Jenny McCarthy - Actress, Activist, and Model - Dedicates bforacure's ‘breasts are beautiful' to Help Raise Money for Breast Cancer Charities
7. Combo hormone therapy has increased breast cancer risk over estrogen alone
8. New drug combo targets multiple cancers
9. FDA Approves First Combo Drug for Diabetes, Cholesterol
10. Drug Combo Might Fight Aggressive Breast Cancer More Safely
11. For Some Prostate Cancer Patients, Combo Treatment Improves Survival
Post Your Comments:
Related Image:
Tender Breasts From Combo HRT Linked to Higher Cancer Risk
(Date:6/26/2016)... , ... June 26, 2016 , ... PawPaws brand ... new product that was developed to enhance the health of felines. The formula is ... The two main herbs in the PawPaws Cat Kidney Support Supplement Soft ...
(Date:6/25/2016)... ... ... temporary closing of Bruton Memorial Library on June 21 due to a possible lice infestation, ... aspect of head lice: the parasite’s ability to live away from a human host, and ... necessary one in the event that lice have simply gotten out of control. , As ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain ... for a minimum wage raise to $12 an hour by 2020 and then adjusting it ... the lost value of the minimum wage, assure the wage floor does not erode again, ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... -- Dehaier Medical Systems Ltd. (NASDAQ: DHRM ... sells medical devices and wearable sleep respiratory products in ... agreement with Hongyuan Supply Chain Management Co., Ltd. (hereinafter ... 2016, to develop Dehaier,s new Internet medical technology business. ... leverage Hongyuan Supply Chain,s sales platform to reach Dehaier,s ...
(Date:6/24/2016)... PUNE, India , June 24, 2016 ... "Pen Needles Market by Type (Standard Pen Needles, Safety ... 12mm), Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase ... published by MarketsandMarkets, This report studies the market for ... is expected to reach USD 2.81 Billion by 2021 ...
Breaking Medicine Technology: