Navigation Links
Tender Breasts From Combo HRT Linked to Higher Cancer Risk
Date:11/18/2011

FRIDAY, Nov. 18 (HealthDay News) -- Women who develop breast tenderness after starting combination estrogen and progestin menopause therapy have a 33 percent higher risk of developing breast cancer than those who don't experience breast tenderness, a new study says.

It also found that new-onset breast tenderness was not associated with increased breast cancer risk among women taking estrogen alone.

The findings, based on an analysis of data from more than 16,600 women on the combination therapy and nearly 10,750 taking estrogen alone, appear in the Nov. 17 online edition of the journal Breast Cancer Research and Treatment.

"This study showed that developing new breast tenderness after the start of hormone therapy was associated with increased breast cancer risk only in women on the combination estrogen plus progestin therapy, not estrogen therapy alone," study first author Dr. Carolyn Crandall, a professor of general internal medicine and a scientist with the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, said in a UCLA news release.

However, the association between breast tenderness and increased cancer risk does not mean that there is a cause-and-effect relationship.

A study published last month by Crandall found that new-onset breast tenderness was much more pronounced in women receiving the combination therapy than in those receiving estrogen alone. The association between new-onset breast tenderness and breast-density changes was also more pronounced in women receiving the combination therapy.

"The consistent theme we've run across throughout these studies is that estrogen and progestin compared to estrogen alone have a more marked effect on breast tissue," Crandall said. "One theory is that there may be more growth of breast tissue, making the breasts more dense, when women take the combination therapy."

Higher breast density is linked with a higher risk of breast cancer.

Crandall stressed that women taking hormone therapy have only a slight risk of developing breast cancer overall.

"We don't want to incite panic, because breast cancer is rare in women taking hormone therapy, but the point is that women are terrified of getting breast cancer as a result of menopausal hormone therapy," Crandall said.

"Where I think this (new) study would be important is for women already on either combination hormone therapy or estrogen alone," Crandall added. "If they do develop breast tenderness, it would be good for them to know the results of this study and to consider discussing them with their physician."

Women on hormone therapy who develop new-onset breast tenderness should be sure to get their regular clinical breast exams and mammograms, Crandall advised.

More information

The U.S. National Institute of Child Health and Human Development has more about hormone replacement therapy.

-- Robert Preidt

SOURCE: University of California, Los Angeles, news release, Nov. 16, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Breast tenderness in women getting combo hormone therapy associated with increase in breast density
2. When Size Matters, Men Can Turn to Penile Extenders: Study
3. Noninvasive extenders are better than surgery for men who want a longer penis
4. Bartenders may have role in assisting troubled war veterans
5. Denser Breasts Raise Odds of Second Breast Cancer, Study Finds
6. Jenny McCarthy - Actress, Activist, and Model - Dedicates bforacure's ‘breasts are beautiful' to Help Raise Money for Breast Cancer Charities
7. Combo hormone therapy has increased breast cancer risk over estrogen alone
8. New drug combo targets multiple cancers
9. FDA Approves First Combo Drug for Diabetes, Cholesterol
10. Drug Combo Might Fight Aggressive Breast Cancer More Safely
11. For Some Prostate Cancer Patients, Combo Treatment Improves Survival
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tender Breasts From Combo HRT Linked to Higher Cancer Risk
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance ... management, will showcase a range of technology and learning solutions at the 68th ... and Expo to be held October 14–18, 2017 at the Mandalay Bay Resort ...
(Date:10/12/2017)... CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... cold therapy products, announced today the introduction of an innovative new design of the ... multipurpose pad so you get maximum comfort while controlling your pain while using cold ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the ... medical article to the newly revamped Cosmetic Town journal section, featuring ... transplant procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... of Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. OnSite ... program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at the ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... of California Berkeley, and other leading institutions in announcing the launch of the ... to change the way animals are raised for food. , Founding members of ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... , Oct. 2, 2017  AllianceRx Walgreens Prime, the ... by Walgreens and pharmacy benefit manager Prime Therapeutics LLC ... brand, which included the unveiling of new signage at ... as well as at a few other company-owned facilities ... brand to patients, some of whom will begin to ...
(Date:9/28/2017)... 2017 Hill-Rom Holdings, Inc. (NYSE: HRC), will ... and webcast on Friday, November 3, 2017, beginning at ... at approximately 8:30 a.m. (CDT) / 9:30 a.m. (EDT). ... financial performance and guidance for 2018, Hill-Rom executives will ... operational performance, and long-range financial outlook through 2020. ...
(Date:9/27/2017)... and NEW YORK , Sept. 27, 2017 /PRNewswire/ ... health and big data solutions, today announced that its MyDario product is ... your local TV listings for when The Dr. Oz Show airs in ... The nine-time ... month. ...
Breaking Medicine Technology: