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Temple study compares deep vein thrombosis therapies
Date:7/21/2014

blood transfusion (a measure of bleeding) was 11.1 percent for the catheter group, versus 6. 5 percent for the medical group.

  • The rate of pulmonary embolism (clot in the lung) was 17.9 percent versus 11.4 percent.

  • The rate of intracranial hemorrhage (bleeding in the brain) was 0.9 percent for the catheter group versus 0.3 percent for the medical therapy group.

  • The length of hospital stay was longer for those patients who had the catheter procedure 7 days versus 5.1 for the other group.

  • Hospital charges were also higher in the catheter group: $85,553 versus $29,369.

    The researchers found that rate of CDT utilization for treating DVT went from 2.3 percent in 2005 to 5.9 percent in 2010. Over that same period, the mortality rate for patients who had CDT went down, which is probably a reflection in a refinement in catheter based technologies and increased operator experience. However the rate of bleeding continued to remain higher in this group of patients. Patients who had the procedure at a higher-volume center tended to do better, the study found.

    Dr. Bashir said that some patients with DVT clearly benefit from the catheter based procedure, but he said patients needed to be carefully selected. His team concluded that more research is needed to sort out the risks versus the benefits of the procedure.

    "In light of the findings of this study, it is imperative that the magnitude of benefit from CDT has to be substantiated in order to justify the increased upfront resource utilization and bleeding risk of this therapy," the researchers wrote. "In the absence of such data, it may be reasonable to restrict this form of therapy to those patients who have a low bleeding risk and have a high risk of PTS," such as patients with clots at or above their groins.

    "I think all patients with leg clots should be informed about the risks of developing PTS and its consequences and the risks of catheter-based clo
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  • Contact: Kathleen Duffy
    Kathleen.Duffy@tuhs.temple.edu
    267-800-4359
    Temple University Health System
    Source:Eurekalert

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