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Temple scientists receive $11.5 million grant for heart failure research
Date:5/22/2014

(Philadelphia, PA) Innovative treatments for heart failure are lacking, leaving the nearly six million Americans who suffer from the condition with little hope for a cure. But thanks to an $11.5-million Program Project Grant (PPG) from the National Heart, Lung, and Blood Institute (NHLBI), scientists at Temple University School of Medicine are now set to further their investigation of key molecular mechanisms in heart failure, an effort that is expected to lead to the development of new heart therapies.

The Principal Investigator on the new PPG award is Dr. Walter J. Koch, PhD, The William Wikoff Smith Chair in Cardiovascular Medicine, Professor and Chair of the Department of Pharmacology, and Director of the Center for Translational Medicine at Temple University School of Medicine (TUSM). Dr. Koch is working alongside two other Temple researchers on the Program Project Grant Dr. Steven R. Houser, PhD, FAHA, Senior Associate Dean for Research, Professor and Chair of the Department of Physiology, and Director of the Cardiovascular Research Center at TUSM; and Dr. Arthur M. Feldman, MD, PhD, Executive Dean of TUSM, and Chief Academic Officer of Temple University Health System.

Each of the scientists is leading a specific project for the grant, with all three projects being natural outgrowths of ongoing research in their individual laboratories. The three projects focus on signaling pathways implicated in cardiac injury and repair, and they likely intersect in heart failure pathology, underscoring the significance of the collaborative research effort.

"The Program Project Grant give us the opportunity to develop novel approaches to treat ischemic heart disease," explained Dr. Houser. "Our goal will be to have new therapeutics ready for patients through our PPG."

The new award represents the second round of PPG funding for the three researchers. Over the course of their previous funding cycle, Drs. Feldman, Houser, and Koch de
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Contact: Jeremy Walter
Jeremy.Walter@tuhs.temple.edu
215-707-7882
Temple University Health System
Source:Eurekalert

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