Navigation Links
Temple researchers show targeted cancer drug may stunt heart's ability to repair itself
Date:11/6/2012

subsequently treated bone marrow stem cells, heart stem cells, and heart muscle cells (myocytes) with sorafenib in the laboratory dish. The drug blocked both types of stem cells from growing, but had no effect on normal heart muscle cells. This meant that the drug likely doesn't affect normal heart cells that were not damaged and under repair, Dr. Houser pointed out. "Injury activates the proliferation of the stem cells," he said. "We think it's something about the repair process that the drug affects."

He and his team would like to find drugs that could be taken alongside cancer drugs such as sorafenib that would reduce adverse effects on heart stem cells. At this time, they are developing a program to screen candidate agents. "Ideally, we could help physicians predict which patients are at higher risk for these effects, and find better ways to screen patients," Dr. Houser said.

The investigators next plan to test therapies to stimulate repair and protect hearts from potential damage from such cancer drugs.


'/>"/>
Contact: Steven Benowitz
steven.benowitz@tuhs.temple.edu
215-707-4784
Temple University Health System
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Penn-Temple team discovers gatekeeper for maintaining health of cell energy source
2. NIH awards $20 million over 5 years to train next generation of global health researchers
3. Researchers develop a new cell and animal model of inflammatory breast cancer
4. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
5. Researchers Find Gene Mutations That May Be a Key to Autism
6. Researchers find evidence of banned antibiotics in poultry products
7. NJ stroke researchers report advances in spatial neglect research at AAN Conference
8. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
9. Researchers Map Brain Regions Linked to Intelligence
10. Researchers ID Genes That May Determine Mental Illness
11. Researchers Develop Blood Test for Depression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2014)... (PRWEB) November 24, 2014 Global ... 6.19 billion by 2020, according to a new ... rates of cardiac arrhythmias clubbed with growing global ... this market. Though still in the budding stage, ... rise in usage rates in the recent times, ...
(Date:11/24/2014)... 2014 Residents of retirement communities in ... year’s SENIORS GOT TALENT, an annual online talent competition ... players to classic crooners, to seniors partying on a ... are indeed living young. , “SENIORS GOT TALENT, while ... cash prize, has always been about highlighting the vibrancy ...
(Date:11/24/2014)... York (PRWEB) November 24, 2014 The ... by the Family and Children's Association to ... as soap, shampoo, mouthwash and other such items.The Association's ... who are home bound, living in nursing homes, assisted ... to greatly enhance the well being of seniors throughout ...
(Date:11/24/2014)... SafeHandles™ announced that they will be featured ... Jr, airing via Discovery Channel. Dates and show times ... non-invasive, replaceable, and affordable germ protective device. This segment ... and adhesives to promote hand hygiene in high traffic ... SafeHandles is the desire to make a positive impact ...
(Date:11/24/2014)... Pittsburgh, PA (PRWEB) November 24, 2014 ... as he was trying to cross the street in ... "The driver never saw him. I came up with ... easily visible at night." , He developed the Safety ... night or in low-lighting conditions. The device ensures that ...
Breaking Medicine News(10 mins):Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 2Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 3Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 4Health News:Nursing Homes & Assisted Living Retirement Communities Enter Seniors Guide's Seniors Got Talent 2Health News:Nursing Homes & Assisted Living Retirement Communities Enter Seniors Guide's Seniors Got Talent 3Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 2Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 3Health News:New Episode of Innovations TV Series to Feature SafeHandles™ 2
... the world will gather for Digestive Disease Week 2010 ... May 1 to May 5, 2010, at the Ernest ... the annual meeting of the American Gastroenterological Association (AGA) ... world. AGA researchers will present exciting, cutting-edge data during ...
... symptoms, could help speed diagnosis, findings show , FRIDAY, ... technique can identify changes in speech associated with the ... found. , "This is a noninvasive, reliable and accurate ... a few simple sentences," Shimon Sapir, of the department ...
... ... to child health advocacy , ... Vancouver, BC (Vocus) April 30, 2010 -- Pediatric experts from Children,s National ... 2010 Pediatric Academic Societies Annual Meeting—one of the largest annual meetings of health experts focused ...
... ... 18th during Hearing Aid Roundup , ... Braunfels, TX (Vocus) April 30, 2010 -- Estes Audiology and the Windcrest SERTOMA ... down to the Hearing Aid Roundup at Estes Audiology in New Braunfels on Tuesday, May 18, ...
... fares worse than many other countries, CDC experts say , ... latest year for which figures are available, about seven infants ... 3 percent drop from 2005 and the lowest infant death ... the drop in infant mortality was significant, the United States ...
... washes , FRIDAY, April 30 (HealthDay News) -- Rinsing the ... way to try to reduce allergy symptoms and sinus infections ... simple treatment might also help prevent ear infections in young ... received an average of four nasal irrigations four days a ...
Cached Medicine News:Health News:AGA presents cutting-edge research during DDW 2Health News:AGA presents cutting-edge research during DDW 3Health News:AGA presents cutting-edge research during DDW 4Health News:Voice Analysis May Allow Early Detection of Parkinson's 2Health News:Experts from Children's National Medical Center to present at Pediatric Academic Societies' Annual Meeting 2Health News:Experts from Children's National Medical Center to present at Pediatric Academic Societies' Annual Meeting 3Health News:Estes Audiology and SERTOMA Club Windcrest Celebrate Better Hearing and Speech Month with Hearing Aid Roundup 2Health News:Estes Audiology and SERTOMA Club Windcrest Celebrate Better Hearing and Speech Month with Hearing Aid Roundup 3Health News:U.S. Infant Deaths on the Decline 2Health News:U.S. Infant Deaths on the Decline 3Health News:Nasal Saline Rinses Reduce Ear Infections in Kids 2Health News:Nasal Saline Rinses Reduce Ear Infections in Kids 3
(Date:11/24/2014)... 2014  GlySens Incorporated announced today that it has ... the National Institute of Diabetes and Digestive and Kidney ... Health (NIH).  The grant is intended to support human ... term implantable glucose monitoring system.  Final preparations for launch ... to begin before the end of 2014. ...
(Date:11/23/2014)... Nov. 23, 2014 Anthera Pharmaceuticals, Inc. (Nasdaq: ... F. Truex , President and Chief Executive Officer, will ... Jaffray Healthcare Conference. Anthera will present ... Palace Hotel in New York City ... Anthera Pharmaceuticals is a biopharmaceutical company focused on developing ...
(Date:11/22/2014)... NEWTOWN, Pennsylvania , 21 de noviembre de ... servicios de ensayos clínicos externalizados y tecnologías eClinical, ... su aproximación de ,seguimiento inteligente, para el seguimiento ... El seguimiento inteligente amplía el concepto del seguimiento ... simple reducción de las visitas de seguimiento o ...
Breaking Medicine Technology:GlySens Incorporated Awarded $2 Million Grant from the National Institutes of Health 2Anthera Pharmaceuticals to Present at Annual Piper Jaffray Healthcare Conference 2El 'seguimiento inteligente' consigue un excelente momento 2El 'seguimiento inteligente' consigue un excelente momento 3
... TSX: BMR, TORONTO, July 10, 2007 /PRNewswire-FirstCall/ ... to the,development and commercialization of cancer therapies, ... independent team in,Basel, Switzerland validates tenascin as ... new treatments for glioblastoma,multiforme (GBM). , The ...
... 2007 - BusinessWeek,published an article on July ... companies to be first to bring to,market ... angiogenesis therapies are being pursued by,Sanofi-Aventis, Boston ... highlights a very promising new biological,therapy for ...
Cached Medicine Technology:Molecular Target of Bradmer's Neuradiab Further Validated by,Independent Findings 2Molecular Target of Bradmer's Neuradiab Further Validated by,Independent Findings 3Molecular Target of Bradmer's Neuradiab Further Validated by,Independent Findings 4BusinessWeek Article Highlights Promising Breakthrough Treatment,for Advanced Coronary Artery Disease 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: