Navigation Links
Temple-led study finds no benefit in taking statin drugs for COPD exacerbation prevention
Date:5/18/2014

g the morbidity and mortality associated with acute COPD exacerbations.

"That turns out not to be the case," Dr. Criner said. "This study suggests that statins' purported non-cholesterol-lowering anti-inflammatory effects do not extend to COPD."

The study, funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, was carried out at 45 sites in the U.S. and Canada, with Temple leading the way in the number of enrolled participants. The Canadian Institutes of Health Research also provided funding for the Canadian clinical centers. Of the study's 877 participants, 430 took 40 mg. daily of simvastatin, a common statin drug used to prevent heart attack and stroke, and 447 took a daily placebo, or dummy pill. They were followed for at least 12 months, and some as long as 36 months.

The study enrolled patients with moderate to severe COPD who were not taking statins for other medical indications. Volunteers, ranging in age 40 to 80, were current or former smokers, and met one of the following other criteria: they used oxygen supplementation either currently or in the past, they were prescribed systemic corticosteroids and or antibiotics in the past year, or had been at the ER or hospitalized with a flare-up in the past year. The study excluded patients with diabetes or coronary heart disease, as well as patients who were not taking a statin drug but should have been because of their cardiovascular risk profile.

The study's primary outcomes measure was the rate of exacerbation, defined as the number of exacerbation events per participant year. Secondary outcome measures included time to first exacerbation, severity of exacerbations, quality of life and changes in lung function as measured by spirometry. Study participants, who all continued with their usual COPD treatment and care, were tracked throughout the study by clinic visits every three months and monthly phone calls.

Among the findi
'/>"/>

Contact: Jeremy Walter
Jeremy.Walter@tuhs.temple.edu
215-707-7882
Temple University Health System
Source:Eurekalert

Page: 1 2 3 4 5 6

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... German . ... the ,International Space Station Research Competition, with their project ... scientists will see the International Space Station crew perform ... two proteins of the hepatitis C virus under microgravity ... Space Station is scheduled to lift off from Cape ...
(Date:9/18/2014)... 2014 According to a new market report ... - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, ... was valued at USD 77607.7 million in 2013 and is ... to 2020, to reach an estimated value of USD 115474.9 ... market is growing at a rapid pace due to increasing ...
(Date:9/18/2014)... September 18, 2014 “Awesome” is the ... (Smart Teens Accepting Responsibility Today) Internship Program at ARDX ... Darcy C. describe the program as “Inspirational” and “Life-changing,” ... idea about what they would be doing during their ... do food runs and other mindless tasks,” but, instead ...
(Date:9/18/2014)... HealthDay Reporter WEDNESDAY, ... may be associated with increased odds of developing Parkinson,s ... research suggests. The study, which did not prove ... suggested that the migraine-Parkinson,s association was stronger in women ... warning sign of a pending attack that includes flashes ...
(Date:9/18/2014)... 2014 How much is a serving? ... the factors contributing to the obesity epidemic in the ... serving and how to manage portion size during the ... 3 at Humility House, 755 Ohltown Road, Austintown. , ... the informational discussion and answer questions from 12:30 to ...
Breaking Medicine News(10 mins):Health News:Hepatitis C virus proteins in space 2Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 2Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 3Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 4Health News:ARDX Internship Helps Students to START on the Right Business Path 2Health News:ARDX Internship Helps Students to START on the Right Business Path 3Health News:ARDX Internship Helps Students to START on the Right Business Path 4Health News:Are Migraines in Middle Age Tied to Raised Parkinson's Risk Later? 2Health News:Are Migraines in Middle Age Tied to Raised Parkinson's Risk Later? 3Health News:HMHP Workshop Addresses Portion Control 2
... and poultry products from Taiwan, Hong Kong, and four ... to 17.//,The step has come as a precaution against ... ,Last month, Pakistan put a similar ban on ... Indonesia, Cambodia, Laos, Russia, Kazakhstan, Mongolia, Turkey, Greece and ...
... is a major factor increasing the cholesterol level in ... by the body in moderate amounts, can lead to ... Lena Brydon of University College London examined 199 healthy ... to stress and whether their reaction can increase cholesterol ...
... bird flu, even as the government has given approval to ... ,The latest outbreaks of the deadly H5N1 strain of the ... province of Yunnan and the northwestern region of Ningxia, the ... died in Yunnan's Chuxiong district Thursday, and 230 died in ...
... of its super-speciality hospital chain with a 280-bed hospital ... ,"We have embarked on the construction of a ... be ready by 2007-end. We also plan Greenfield projects ... president, told IANS., ,Unlike the existing 110-bed cardiac ...
... of more than 1,200 children, whose organs were removed after ... an average of about ?2,900 in a compensation deal announced ... is the apex body had fought the cases involving ... ago to a total figure of around ?3.6 million for ...
... could be putting their health at risk by failing ... other health professionals.// ,The survey of more than ... Professions Council (HPC), found that about 81% of people ... were oblivious to whether they were properly qualified to ...
Cached Medicine News:Health News:Wockhardt Group Plans Hospital In Delhi By End-2007 2Health News:Organ Scandals Compensation And The Aftermath 2Health News:Credentials Of Specialists Need To Be Checked 2
(Date:9/18/2014)... 18, 2014  KIYATEC announced today that it ... Innovation Research (SBIR) Phase II Contract from the ... institutes and centers that comprise the National Institutes ... two year award, KIYATEC will expand its 3D ... the forefront of cancer therapy strategies: 1) cancer,s ...
(Date:9/18/2014)... 18, 2014  Decision Resources Group finds that Regeneron,s ... (VEGF) agent for wet AMD, is equally likely to ... Genentech,s Lucentis, which is the standard of care for ... (MCO) directors do not identify a clear clinical or ... than Lucentis to be listed on tier 1 or ...
(Date:9/18/2014)... MEETING, Pa. , Sept. 18, 2014 ... trial solutions, was recognized as the Disruptive ... for its ePharmaONE cloud-based eClinical platform. This ... and electronic trial master file (eTMF), a ... solution, and ePharmaSolutions, ReferralPlus+ patient screening and ...
Breaking Medicine Technology:National Cancer Institute Awards KIYATEC Nearly $2M to Advance Predictive Cancer Diagnostics 2National Cancer Institute Awards KIYATEC Nearly $2M to Advance Predictive Cancer Diagnostics 3Regeneron's Eylea and Genentech's Lucentis Are Equally Likely to be Covered on Commercial and Medicare Advantage Plans for Wet AMD 2Regeneron's Eylea and Genentech's Lucentis Are Equally Likely to be Covered on Commercial and Medicare Advantage Plans for Wet AMD 3ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 2ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 3
... OF ELAGOLIX ON BONE MINERAL DENSITY, SAN DIEGO, ... announced today that the elagolix 0603 Phase IIb trial,(Petal ... subject,completed her Week 24 study visit in early June. ... on bone mineral density (BMD) as,the primary endpoint using ...
... Prevention and Control Professionals Cite,Greatest Needs for ... More Environmental Services and Time-Saving High Tech ... than three out of four,(76%) infection prevention ... implemented additional measures to prevent the,transmission of ...
Cached Medicine Technology:Neurocrine Biosciences Completes 'Petal Study' Treatment Phase for Endometriosis 2Neurocrine Biosciences Completes 'Petal Study' Treatment Phase for Endometriosis 3Nationwide Progress Poll Reveals Increased Efforts by Hospitals to Control MRSA Infection 2Nationwide Progress Poll Reveals Increased Efforts by Hospitals to Control MRSA Infection 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: