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'Tell-tail' MRI image diagnosis for Parkinson's disease
Date:4/29/2014

An image similar in shape to a Swallow's tail has been identified as a new and accurate test for Parkinson's disease. The image, which depicts the healthy state of a group of cells in the sub-region of the human brain, was singled out using 3T MRI scanning technology standard equipment in clinical settings today.

The research was led by Dr Stefan Schwarz and Professor Dorothee Auer, experts in neuroradiology in the School of Medicine at The University of Nottingham and was carried out at the Queen's Medical Centre in collaboration with Dr Nin Bajaj, an expert in Movement Disorder Diseases at the Nottingham University Hospitals NHS Trust.

The findings have been published in the open access academic journal PLOS one.

The work builds on a successful collaboration with Professor Penny Gowland at the Sir Peter Mansfield Magnetic Resonance Centre at The University of Nottingham.

'The 'Swallow Tail' Appearance of the Healthy Nigrosome A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T' describes how the absence of this imaging sign can help to diagnose Parkinson's disease using standard clinical Magnetic Resonance Scanners.

Parkinson's disease is a progressive neurodegenerative disorder which destroys brain cells that control movement. Around 127,000 people in the UK have the disease. Currently there is no cure but drugs and treatments can be taken to manage the symptoms.

The challenges of diagnosing Parkinson's

Until now diagnosing Parkinson's in clinically uncertain cases has been limited to expensive nuclear medical techniques. The diagnosis can be challenging early in the course of the condition and in tremor dominant cases. Other non-licensed diagnostic techniques offer a varying range of accuracy, repeatability and reliability but none of them have demonstrated the required accuracy and ease of use to allow translation
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Contact: Lindsay Brooke
lindsay.brooke@nottingham.ac.uk
44-011-595-15751
University of Nottingham
Source:Eurekalert  

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'Tell-tail' MRI image diagnosis for Parkinson's disease
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