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Telik Reports Positive Results From Phase 1 Dose-Escalation Study of TELINTRA Tablets in Myelodysplastic Syndrome
Date:12/8/2007

blood cell transfusion independence or a reduction in transfusion requirements, and one patient achieved platelet transfusion independence. One patient had a complete cytogenetic response.

"A tremendous need exists for new agents that are well-tolerated and efficacious for the treatment of MDS patients," said Azra Raza, M.D., Professor of Medicine and Director - MDS Program at St. Vincent's Comprehensive Cancer Center in New York City, and lead investigator on the TELINTRA Tablets study. "Having treated MDS patients with the intravenous formulation of TELINTRA, and now with the more convenient Tablet formulation, I am hopeful that planned Phase 2 dose-ranging trials will continue to demonstrate the potential for this agent to address early-stage MDS cytopenias as an alternative to blood support and best supportive care."

About TELINTRA

TELINTRA is an investigational small molecule designed to stimulate the production of blood cells in the bone marrow for the potential treatment of cytopenias associated with MDS or chemotherapy. Telik has developed both intravenous and Tablet formulations of TELINTRA, which was discovered through the application of Telik's proprietary TRAP(TM) drug discovery technology.

About Telik

Telik, Inc. of Palo Alto, CA is a biopharmaceutical company focused on discovering, developing and commercializing novel small molecule drugs to treat serious diseases. The company's most advanced drug development candidates are TELCYTA(R), a tumor-activated small molecule product candidate in clinical development for the treatment of advanced ovarian cancer and non-small cell lung cancer; and TELINTRA(R), which is in development for the treatment of cytopenias due to myelodysplastic syndrome or chemotherapy. Telik's product candidates were discovered using its proprietary drug discovery technology, TRAP(TM), which enables the rapid and efficient discovery of small molecule drug candidates. Additional information is avai
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SOURCE Telik, Inc.
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