Navigation Links
Technique May Let More Women Use Tamoxifen
Date:2/23/2009

30% of breast cancers currently don't respond to this type of estrogen-linked drug

MONDAY, Feb. 23 (HealthDay News) -- Researchers have found a way to "switch on" estrogen sensitivity in breast tumor cells, thereby making them vulnerable to the breast cancer drug tamoxifen.

If successful, the technique might someday allow breast cancer patients who don't respond to tamoxifen to benefit from the drug.

"We're excited by the results," said study author Caroline Ford, a member of the department of cell and experimental pathology at Lund University in Malmo, Sweden. "This has implications for the 30 percent of breast cancer patients who are estrogen-receptor negative who currently have a poor prognosis."

Not only might these tumors become amenable to tamoxifen, but they may also respond to other "endocrine" treatments such as aromatase inhibitors, which also interfere with estrogen production in the body.

"We are currently investigating this," Ford said.

The findings may also provide alternatives for the group of women who start out estrogen receptor-positive but later become negative and for whom treatments stop working.

The findings are published in this week's issue of the Proceedings of the National Academy of Sciences.

As Ford noted, a large minority of patients have breast cancer tumors that do not express estrogen receptors. Not only does this make them unresponsive to a variety of treatments now available for estrogen receptor-positive malignancies, but it indicates a more aggressive cancer in general.

Tamoxifen, which has been a gold standard of breast cancer treatment for decades, works by binding to the estrogen receptor. If there is no receptor, however, tamoxifen becomes useless.

Any means of allowing the three out of 10 women whose cancers don't respond to tamoxifen and other endrocrine therapies would be a big advance, experts say.


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Eye-staining technique offers early detection for dry eye syndrome
2. New technique detects specific chromosomal damage, may indicate lung cancer risk
3. The Pharma & Life Sciences Best Practice Database: an Industry Resource for Successful Techniques and Performance Benchmarks for Reaching the Top
4. Latest DES Analysis Stresses Importance of Physicians Well-Trained in Implantation Technique and Patient Follow-Up
5. Accuray Receives FDA Clearance for New Dose Calculation Technique for Body Radiosurgery
6. Radiation therapy technique reduces length of prostate cancer treatment
7. Radiation therapy technique reduces length of prostate cancer treatment
8. IVF technique enables pregnancy without multiple births, Stanford researchers find
9. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
10. UCLA doctor develops new technique to treat varicose veins
11. New technique improves purity of medicines
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Technique May Let More Women Use Tamoxifen
(Date:8/28/2015)... ... August 28, 2015 , ... An article published August ... Paul LaRocco has gone through to open a pizzeria in Westchester. Mr. LaRocco was ... to take several months, but the current process, having already gone on for over ...
(Date:8/28/2015)... , ... August 28, 2015 , ... As reported ... Merz, received FDA clearance for results that last for two years, the longest ... news for patients who are looking for a long-lasting, effective solution for their cellulite, ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... high grade protein with zero fat, carbs, sugar, gluten, lactose or caffeine in ... finalist for the 2015 SupplySide CPG Editor’s Choice Awards. , Five consumer packaged ...
(Date:8/28/2015)... ... , ... Medical Solutions, one of the nation’s largest travel nurse staffing companies, ... Modern Healthcare and will be honored at an awards dinner in Chicago on ... Places to Work in Healthcare program recognizes outstanding employers in the healthcare industry nationwide. ...
(Date:8/28/2015)... Phoenix, Arizona (PRWEB) , ... August 28, 2015 ... ... visibility and increased patient loyalty at a low cost. Personalized with practice contact ... new and existing patients. Dental offices can also incorporate Calendars into seasonal mailings, ...
Breaking Medicine News(10 mins):Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 3Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 3Health News:SmartPractice® Introduces 2016 Calendars for Dental Practice Giveaways 2
... Buffalo scientists have paired up to create technology ... worldwide, developing the first procedure-based, hands-on surgical training ... (HOST), guides surgeons through real-time operative procedures using ... Khurshid Guru, MD, a staff physician in Urology ...
... targeted monoclonal antibodies in combination with existing therapies show ... according to research that will be presented by investigators ... the 2010 meeting of the American Society of Clinical ... antibody to enhance the effectiveness of a breast cancer ...
... ... explosion of celebrity sex tapes and scandals, including the recent release of Kendra Wilkinson,s ... ... the explosion of celebrity sex tapes and scandals, including the recent release of Kendra ...
... ... of all ages active , ... Monica, CA (PRWEB) June 1, 2010 -- Leading youth fitness brand O2 MAX Fitness ... teenagers, and children ranging from ages 2 to early 20s. As with all of their past ...
... against cerebral malaria, a fatal form of malaria in children ... treat. New research points to platelets known for their ... in the disease, stimulating the immune system and turning on ... of blood vessels in the brain, causing brain damage similar ...
... ... ... June 1, 2010 -- Check In Systems, Inc., a leading provider of check ... enhancements to its Medical Check In HIPAA-compliant patient registration kiosk solution. “Medical Check In ...
Cached Medicine News:Health News:Surgeon-engineer team produce training software for robot-assisted surgery 2Health News:Targeted immunotherapy shows promise for metastatic breast, pancreatic cancers 2Health News:Targeted immunotherapy shows promise for metastatic breast, pancreatic cancers 3Health News:Targeted immunotherapy shows promise for metastatic breast, pancreatic cancers 4Health News:Kendra Wilkinson's Sex Tape Raises Awareness About STDs 2Health News:O2 MAX Fitness Announces "90 Days to Healthy" and Unveils a Summer Slate Full of Youth-Oriented Fitness Initiatives 2Health News:O2 MAX Fitness Announces "90 Days to Healthy" and Unveils a Summer Slate Full of Youth-Oriented Fitness Initiatives 3Health News:Rochester advances understanding of deadly form of malaria 2Health News:Rochester advances understanding of deadly form of malaria 3Health News:Check In Systems Enhances Patient Registration Solution 2
(Date:8/28/2015)... , Aug. 28, 2015  IP Shakti, LLC, today ... Logo - ... "Our new corporate identity signifies our transformation into ... first predictive analytics platform for patent claim validity." ... launch of the proprietary AIA Shield™ platform, the Company commenced ...
(Date:8/28/2015)... PITTSBURGH , Aug. 28, 2015 ... announced that its shareholders have approved Mylan,s proposed ... ; TASE) and the related issuance of Mylan ... general meeting of shareholders held today. The transaction ... the extraordinary general meeting. In addition, the transaction ...
(Date:8/28/2015)... and LONDON , August 28, 2015 ... approach seamlessly connects people, technologies ... improving outcomes and the cost of ... PHG AEX: PHIA) today announced its presence at  ESC Congress ... solutions, including Heart Model A.I. , EchoNavigator and IntelliSpace Cardiovascular, ...
Breaking Medicine Technology:IP Shakti, LLC Changes Company Name to Prediqtus, LLC 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 5Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 6Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 7Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 8Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 9Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 2Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 3Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 4
... March 17, 2011 A recently issued patent ... award winning and best selling medical thermometer brand, ... recently been granted U.S. Patent No. 7,787,938, entitled, ... and Trademark Office, adding to the already extensive ...
... VEGAS, March 17, 2011 A new study by Craig ... and North Cypress Medical Center in Houston, presented this week ... the improved photon sensitivity of new detector technologies such as ... dose patient receive from BSGI/MBI studies by 75%.  However, low ...
Cached Medicine Technology:Exergen Granted New Patent for Temporal Artery Thermometers 2New Technologies Open the Door for Low Dose Breast-Specific Gamma Imaging (BSGI) / Molecular Breast Imaging (MBI) 2
... CCR Medical's Articulating Tip Laryngoscopes ... in the Industry. The articulating ... by providing an improved view ... and Fiber Optic styles. We ...
CCR Medical fiberoptic green system laryngoscope handles., ,OUTSTANDING PERFORMANCE, QUALITY, AND PRICING MAKE OUR FIBEROPTIC SELECTION MOST ECONOMICAL....
CCR Medical fiberoptic green system laryngoscope handles., ,OUTSTANDING PERFORMANCE, QUALITY, AND PRICING MAKE OUR FIBEROPTIC SELECTION MOST ECONOMICAL....
CCR Medical fiberoptic green system laryngoscope handles., ,OUTSTANDING PERFORMANCE, QUALITY, AND PRICING MAKE OUR FIBEROPTIC SELECTION MOST ECONOMICAL....
Medicine Products: