Navigation Links
Team to study control of malaria-related parasite growth with $2.1-million NIH grant
Date:1/23/2014

Animal cells similar to those of humans contain a "control room," called the centrosome, which regulates cell replication. Disrupt this core hub and you kill cell division.

That is the simple idea behind a new five-year, $2.1-million National Institutes for Health grant recently awarded to the USF College of Public Health's Department of Global Health and the Florida Center for Drug Development and Innovation.

The National Institute of Allergy and Infectious Diseases-funded study may help identify new factors required for the growth of malaria-related parasites and lead to new therapies to combat malaria, a mosquito-borne tropical disease that exacts a huge toll on human health in developing countries.

The project began with a key discovery by Michael White, PhD, professor of global health at USF Health, and Elena Suvorova, PhD, a research assistant professor at the USF Center for Drug Development and Innovation (CDDI).

They showed that in malaria-related parasites known as Toxoplasma gondii the centrosome is more complex and very different from their human hosts. The parasite hub houses novel factors, including unusual protein kinases, or enzymes, that offer new targets for drug development.

Principal investigator White and co-principal investigator Suvorova will collaborate with newly hired CDDI medicinal chemist Jim Leahy, PhD, an expert in developing drugs against kinases in cancer, and University of Georgia cell biologist Boris Striepen, PhD, to study centrosome control of Toxoplasma growth.


'/>"/>

Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)
Source:Eurekalert  

Page: 1

Related medicine news :

1. Practice makes perfect if you have a partners touch, according to new study
2. Study shows 1 in 5 women with ovarian cancer has inherited predisposition
3. Study could lead to liquid biopsy tests for bladder cancer
4. New study examines patterns of cancer screening in Appalachian women
5. Regenstrief, IU study: Half of hospitalized adults over 65 need surrogate decision-makers
6. Study: Possible new druggable target in Ewings Sarcoma
7. Miriam Hospital study links intimate partner violence and risk of HIV
8. Study reveals how ecstasy acts on the brain and hints at therapeutic uses
9. Study finds troubling relationship between drinking and PTSD symptoms in college students
10. China Laser Equipment Industry Production Capacity to Be 2.77 Times More by 2017 in a New Study at MarketReportsChina.com
11. Study questions anti-cancer mechanisms of drug tested in clinical trials
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Team to study control of malaria-related parasite growth with $2.1-million NIH grant
(Date:10/13/2017)... Rock, AR (PRWEB) , ... October 13, 2017 ... ... firm with locations throughout Arkansas that offers insurance and financial preparation services, is ... benefit the Rock City Rescue organization. , Rock City Rescue is a locally ...
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health ... technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing ... form that can be easily incorporated into liquid products, while reducing costs to end ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills ... specialty vendors and unique items from across the nation, this holiday-themed event will raise ... offered by the VNA. The boutique will be open Saturday, November 4 (10:00 ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
(Date:10/12/2017)... ... ... Planet Fitness, one of the largest and fastest growing franchisors and operators ... location in Covington, LA at 401 N. U.S. Highway 190, in January of 2018. ... in the Holiday Square shopping center. Its location allows it to serve both Covington ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... , Sept. 27, 2017  Commended for their devotion ... notable awards. Ranked as number one in the South Florida ... time in Inc. 5000 yearly list, the national specialty pharmacy ... Armando Bardisa will soon be honored by SFBJ ... Set to receive his award in ...
(Date:9/25/2017)... R.I. , Sept. 25, 2017  EpiVax, ... assessment, vaccine design, and immune-engineering today announced the ... on the development of personalized therapeutic cancer vaccines. ... has provided exclusive access to enabling technologies to ... Eng., MBA will lead EpiVax Oncology as Chief ...
(Date:9/22/2017)... -- AVACEN Medical (AVACEN) announced that its CE-Marked AVACEN ... with the widespread pain associated with fibromyalgia in the ... Essex, England commented, "I had difficulty ... sleep at all, tremendous pain, with every movement sending ... AVACEN 100] enough, how this has and is helping ...
Breaking Medicine Technology: