Navigation Links
Team to study control of malaria-related parasite growth with $2.1-million NIH grant
Date:1/23/2014

Animal cells similar to those of humans contain a "control room," called the centrosome, which regulates cell replication. Disrupt this core hub and you kill cell division.

That is the simple idea behind a new five-year, $2.1-million National Institutes for Health grant recently awarded to the USF College of Public Health's Department of Global Health and the Florida Center for Drug Development and Innovation.

The National Institute of Allergy and Infectious Diseases-funded study may help identify new factors required for the growth of malaria-related parasites and lead to new therapies to combat malaria, a mosquito-borne tropical disease that exacts a huge toll on human health in developing countries.

The project began with a key discovery by Michael White, PhD, professor of global health at USF Health, and Elena Suvorova, PhD, a research assistant professor at the USF Center for Drug Development and Innovation (CDDI).

They showed that in malaria-related parasites known as Toxoplasma gondii the centrosome is more complex and very different from their human hosts. The parasite hub houses novel factors, including unusual protein kinases, or enzymes, that offer new targets for drug development.

Principal investigator White and co-principal investigator Suvorova will collaborate with newly hired CDDI medicinal chemist Jim Leahy, PhD, an expert in developing drugs against kinases in cancer, and University of Georgia cell biologist Boris Striepen, PhD, to study centrosome control of Toxoplasma growth.


'/>"/>

Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)
Source:Eurekalert  

Page: 1

Related medicine news :

1. Practice makes perfect if you have a partners touch, according to new study
2. Study shows 1 in 5 women with ovarian cancer has inherited predisposition
3. Study could lead to liquid biopsy tests for bladder cancer
4. New study examines patterns of cancer screening in Appalachian women
5. Regenstrief, IU study: Half of hospitalized adults over 65 need surrogate decision-makers
6. Study: Possible new druggable target in Ewings Sarcoma
7. Miriam Hospital study links intimate partner violence and risk of HIV
8. Study reveals how ecstasy acts on the brain and hints at therapeutic uses
9. Study finds troubling relationship between drinking and PTSD symptoms in college students
10. China Laser Equipment Industry Production Capacity to Be 2.77 Times More by 2017 in a New Study at MarketReportsChina.com
11. Study questions anti-cancer mechanisms of drug tested in clinical trials
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Team to study control of malaria-related parasite growth with $2.1-million NIH grant
(Date:6/27/2017)... ... 27, 2017 , ... The Kelahan Agency, a privately owned ... of southern New Hampshire, is teaming up with the New Horizons for New ... in the region. , New Horizons for New Hampshire provides a wealth of ...
(Date:6/27/2017)... London, CT (PRWEB) , ... June 27, 2017 ... ... the Alice P. Fabrykiewicz Scholarship Foundation Fundraiser hygiene symposium in Mystic, CT. Covering ... Toback and Urbanski offered their experience in these popular periodontal procedures. Drs. Toback ...
(Date:6/27/2017)... ... June 27, 2017 , ... Today, June 27th is PTSD Awareness Day. Over ... 20% will receive adequate care due to lack of effective treatments, fear of stigma ... all. And left untreated, veterans are at an increased risk for self-destructive behavior, including ...
(Date:6/27/2017)... ... ... Children’s National Health System received top honors in the 2017-18 U.S News ... out of more than 1500 neonatal intensive care units coast to coast. ... to the top performing children’s hospitals in the country. , In addition to ...
(Date:6/26/2017)... ... June 26, 2017 , ... Dr. Martin Bastuba, MD, ... collaboration with the Fertility Center of California, is pleased to announce the addition ... aspiration) and TESA (percutaneous testicular sperm extraction). These minimally invasive treatments are primarily ...
Breaking Medicine News(10 mins):
(Date:6/16/2017)... -- Exactly 50 years ago today, the Monterey Pop Festival opened ... the San Francisco "Summer of Love."  To celebrate the anniversary, ... in strategic market research portals that it will begin delivering ... Northern Light,s "Summer of Love (For Our Customers)."  ... ...
(Date:6/12/2017)... , June 12, 2017 Kineta, Inc., a biotechnology ... Kineta Vice President of R&D and Head of ... Pandemic Preparedness for the Northwest and Beyond meeting ... on June 14, 2017 from 8:30-10:30 AM PDT at the ... Dr. Bedard will be joined by other ...
(Date:6/8/2017)... MAITLAND, Fla. , June 8, 2017  Less ... ransomware attack that hit more than 200,000 companies, including hospital ... is being heralded as one of the largest online ... technology in the healthcare market, it is imperative that ... can protect their data from this — and many ...
Breaking Medicine Technology: