Navigation Links
Team led by LA BioMed scientist develops novel approach to study neurological disorders
Date:6/24/2010

LOS ANGELES (June 24, 2010) A team led by a Los Angeles Biomedical Research Institute (LA BioMed) researcher developed a novel approach to efficiently identify disease relevant genes in human complex neurological disorders and demonstrated the effectiveness of this method by applying it to Amyotrophic Lateral Sclerosis (ALS), or Lou Gehrig's Disease, according to a new study reported online in the journal, Human Molecular Genetics.

The approach developed by the scientists uses cutting-edge techniques to study human tissue and animal models and made possible several important findings in the course of the study.

"With this novel approach, we were able to identify new genes and proteins specifically found with a sporadic form of ALS," said LA BioMed investigator Stanislav L. Karsten, PhD, one of the study's corresponding authors. "This approach made possible the first demonstration that some of the disease specific genes found in the spinal cord may also be detected in the peripheral blood prior to the development of the disease. This finding could be vital information because it suggests that a prognostic or diagnostic test for ALS may be possible."

ALS is a neurological disorder characterized by progressive degeneration of motor neuron cells in the spinal cord and brain, which ultimately results in paralysis and death. Approximately 5,600 people in the U.S. are diagnosed with the disease each year. The sporadic form of the disease affects about two-thirds of people with ALS. It is characterized by a deterioration of upper and lower motor neuron cells.

Currently, there is no one test or procedure to ultimately establish the diagnosis of ALS. It is through a clinical examination and series of diagnostic tests, often ruling out other diseases that mimic ALS, that a diagnosis can be established.

"By developing new methods to examine disease relevant genes in neurological disorders, we move closer to unlocking the mysteries of ALS and other neurological diseases," said Dr. Karsten. "This study provides us new clues to continue to investigate the causes and to seek the therapies that can make a difference in the lives of those suffering from neurological disorders."


'/>"/>

Contact: Laura Mecoy
Lmecoy@issuesmanagement.com
310-546-5860
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)
Source:Eurekalert  

Related medicine news :

1. BioMedix Vascular Solutions, Inc. Invited to Participate in the California P.A.D. Task Force Committee
2. Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers
3. Entest BioMedical Enters into LOI with Advanced Light Devices to Develop Laser Platform for Stem Cell / Laser COPD Treatment
4. Therapure Biopharma Inc. signs multi-year manufacturing agreement with LFB Biomedicaments
5. Autism-Supplements.com and Generation Rescue Work Together to Raise Money for Biomedical Autism Treatments
6. Lefkowitz, BBVA Foundation Frontiers of Knowledge Award in Biomedicine
7. Money for Biomedical Research Cut in Recent Years
8. ASH to Encourage High School Students to Pursue Biomedical Research Through Special Symposium and Science Curriculum
9. BioMedSearch.com Launches
10. The Foundation for Biomedical Research Releases New Breast Cancer PSA
11. BioMed Realty Trust Reports Fourth Quarter and Full-Year 2009 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Team led by LA BioMed scientist develops novel approach to study neurological disorders
(Date:8/21/2017)... (PRWEB) , ... August 21, 2017 , ... The American ... Network (AHN), a Highmark Health company, to its Board of Trustees for a ... not-for-profit association of health care provider organizations and individuals that are committed to the ...
(Date:8/20/2017)... ... 20, 2017 , ... A total solar eclipse will occur across the U.S. on ... moon moves between the sun and Earth. This rare event will be magnificent to witness, ... keep you safe on the road during the total eclipse of the sun. , 1. ...
(Date:8/19/2017)... ... August 19, 2017 , ... ... Jr., will feature the Aurum Group in an upcoming episode, slated to air ... of Innovations will feature the Aurum Group; a company committed to supporting dentistry ...
(Date:8/19/2017)... New York, New York (PRWEB) , ... August ... ... Fruit Street Health has announced that it is the first organization with pending ... the CDC’s National Diabetes Prevention Program (“DPP”) via group telehealth classes and live ...
(Date:8/19/2017)... NJ (PRWEB) , ... August 19, 2017 , ... ... Park, NJ, is a diverse community of over 1,000 passionate employees, caregivers, volunteers, ... aging. After Parker at Stonegate changed ownership, it was time to refresh the ...
Breaking Medicine News(10 mins):
(Date:8/17/2017)... , Aug. 17, 2017 Bio-Ess Laboratories, LLC Chief Science Officer, ... titer and present new data on Cell-Ess® Universal Titer Boost ... Boston, MA August 21-25.  The Bioprocessing Summit convenes more ... challenges. ... ...
(Date:8/15/2017)...  Axium Pharmaceuticals Inc., the creator of the drug Truveta ... stages of an IPO. The United States ... cost of a prescription epilepsy drug being $450.00-$1200.00 for a one month ... AXIUM PHARMACEUTICALS, INC ... Another staggering figure is the fact that Americans spent $42 billion on ...
(Date:8/14/2017)... PETACH TIKVAH, Israel , Aug. 15, ... leading developer of adult stem cell technologies for neurodegenerative ... June 30, 2017. ... our pivotal Phase 3 trial to investigate NurOwn ® ... and Chief Executive Officer of BrainStorm. "We have agreements ...
Breaking Medicine Technology: