Navigation Links
Team led by LA BioMed scientist develops novel approach to study neurological disorders
Date:6/24/2010

LOS ANGELES (June 24, 2010) A team led by a Los Angeles Biomedical Research Institute (LA BioMed) researcher developed a novel approach to efficiently identify disease relevant genes in human complex neurological disorders and demonstrated the effectiveness of this method by applying it to Amyotrophic Lateral Sclerosis (ALS), or Lou Gehrig's Disease, according to a new study reported online in the journal, Human Molecular Genetics.

The approach developed by the scientists uses cutting-edge techniques to study human tissue and animal models and made possible several important findings in the course of the study.

"With this novel approach, we were able to identify new genes and proteins specifically found with a sporadic form of ALS," said LA BioMed investigator Stanislav L. Karsten, PhD, one of the study's corresponding authors. "This approach made possible the first demonstration that some of the disease specific genes found in the spinal cord may also be detected in the peripheral blood prior to the development of the disease. This finding could be vital information because it suggests that a prognostic or diagnostic test for ALS may be possible."

ALS is a neurological disorder characterized by progressive degeneration of motor neuron cells in the spinal cord and brain, which ultimately results in paralysis and death. Approximately 5,600 people in the U.S. are diagnosed with the disease each year. The sporadic form of the disease affects about two-thirds of people with ALS. It is characterized by a deterioration of upper and lower motor neuron cells.

Currently, there is no one test or procedure to ultimately establish the diagnosis of ALS. It is through a clinical examination and series of diagnostic tests, often ruling out other diseases that mimic ALS, that a diagnosis can be established.

"By developing new methods to examine disease relevant genes in neurological disorders, we move closer to unlocking the mysteries of ALS and other neurological diseases," said Dr. Karsten. "This study provides us new clues to continue to investigate the causes and to seek the therapies that can make a difference in the lives of those suffering from neurological disorders."


'/>"/>

Contact: Laura Mecoy
Lmecoy@issuesmanagement.com
310-546-5860
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)
Source:Eurekalert  

Related medicine news :

1. BioMedix Vascular Solutions, Inc. Invited to Participate in the California P.A.D. Task Force Committee
2. Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers
3. Entest BioMedical Enters into LOI with Advanced Light Devices to Develop Laser Platform for Stem Cell / Laser COPD Treatment
4. Therapure Biopharma Inc. signs multi-year manufacturing agreement with LFB Biomedicaments
5. Autism-Supplements.com and Generation Rescue Work Together to Raise Money for Biomedical Autism Treatments
6. Lefkowitz, BBVA Foundation Frontiers of Knowledge Award in Biomedicine
7. Money for Biomedical Research Cut in Recent Years
8. ASH to Encourage High School Students to Pursue Biomedical Research Through Special Symposium and Science Curriculum
9. BioMedSearch.com Launches
10. The Foundation for Biomedical Research Releases New Breast Cancer PSA
11. BioMed Realty Trust Reports Fourth Quarter and Full-Year 2009 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Team led by LA BioMed scientist develops novel approach to study neurological disorders
(Date:10/12/2017)... ... October 12, 2017 , ... ... for healthcare compliance program management, will showcase a range of technology and learning ... Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 at ...
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, ... post-acute health care, have expanded their existing home health joint venture through an ... has been operating a joint venture home health company with Asante, delivering clinically ...
(Date:10/12/2017)... ... , ... HMP , a leader in healthcare events and education, today announced ... Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie ... competition recognizes editorial and design excellence across a range of sectors. This year’s program ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and Grand ... Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness will be ... Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry Autograph Collection ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)...  South Korean-based healthcare product Development Company I.M. Lab ... Kickstarter. The device will educate the user about ,proper, ... efficiency compared to the dated and pricey CPR training ... of the compression for a more informed CPR training. ... raise $5,000. cprCUBE ...
(Date:10/2/2017)... Mich. , Oct. 2, 2017 Diplomat ... 8th Day Software and Consulting, LLC , and ... 8th Day Software, based in Tennessee ... LLC. 8th Day expands EnvoyHealth,s service offerings for health ... development. "In an ...
(Date:10/2/2017)... , Oct. 2, 2017 Halo Labs announces the European ... system called the HORIZON at MIBio 2017 in Cambridge, ... and visible particulate matter in biopharmaceutical samples with unprecedented speed and ... the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: