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Taxol-type drugs give slight boost to survival rates in early breast cancer
Date:10/16/2007

the course of a lifetime. Thirty percent of those diagnosed will die from it.

Dickersin said that while research reviews often serve as guidance tools for doctors in clinical practice, they should also help researchers identify unanswered questions. It is still unclear which women gain the most benefit from the inclusion of taxanes, Nowak said.

Also unknown is whether taxanes are more beneficial to women whose tumors grow in response to the hormone estrogen or to those whose tumors are not hormone-sensitive, and whether these drugs are more or less effective in women with certain genetic predispositions to the disease.

Nowak and one of the other four review authors report that drug companies that manufacture taxanes have previously paid them for some travel expenses and lectures. Dickersin who is director of the U.S. Cochrane Center, one of 12 such centers around the world said that Cochrane rules on allowable potential conflicts of interest are much stricter than other guidelines, including those of many medical journals and organizations.


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Contact: Lisa Esposito
hbns-editor@cfah.org
Center for the Advancement of Health
Source:Eurekalert

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