Navigation Links
Targeting the Ewing sarcoma family of tumors
Date:6/30/2011

NEW YORK The Max Cure Foundation and the Samuel Waxman Cancer Research Foundation have partnered to establish a fund in pediatric cancer research. With that goal in mind, the two Foundations are proud to announce the award of $100,000 to Erwin G. Van Meir, Ph.D., of Emory University School of Medicine in Atlanta. Van Meir's research aims to reprogram Ewing sarcoma using a small molecule that will target the Ewing sarcoma family of tumors (ESFT) oncoprotein.

Ewing sarcoma, a type of cancer that forms in the bone or soft tissue, affects primarily young children and adolescents. Though current treatment options have prolonged five-year survival rates in patients, many face long-term affects from surgery, chemotherapy and radiation, including risk of second cancers from therapy. For patients whose disease has spread to other organs, there's a lack of effective treatment options. In addition, for some survivors, the disease can recur.

Van Meir and his colleagues propose to reprogram the ESFT cancer stem cells using a small molecule known as KCN1, which targets the oncoprotein found in the genetic signature of ESFT. Their research will identify a new class of drugs to induce cell death and stop the proliferation of Ewing sarcoma stem cells.

"Van Meir's research offers patients the real promise of a cure one day by identifying the root cause of cancer and eradicating the cancer stem cell, which falls in line with the mission of the Foundation" said Samuel Waxman, M.D., the Founder and the Scientific Director of the SWCRF.

"My grandson Max, who, on the eve of his fourth birthday was diagnosed with an extremely rare form of B-cell Lymphoma, was the inspiration for The Max Cure Foundation," said Richard Plotkin, vice chairman of The Max Cure Foundation. "As Max bravely endured two years of treatment which ultimately led to his remissionmy family went into action to raise funds for pediatric cancer research. This grant is the first of three collaborative grants we're committed to sponsoring with SWCRF so that other children will not have to experience long, painful and invasive cancer treatments."


'/>"/>

Contact: Jenny Song
jsong@waxmancancer.org
212-867-4502
Samuel Waxman Cancer Research Foundation
Source:Eurekalert

Related medicine news :

1. Latest data from Cedars-Sinai vaccine study supports immune targeting of brain tumors
2. Study confirms safety, cancer-targeting ability of nutrient in broccoli, other vegetables
3. NIH grant for the move toward clinical trials targeting the lysosomal storage disease MPSIIIB
4. Targeting top 911 callers can trim cost, improve patient care
5. Cancer-targeting investigational nanoparticle receives FDA IND approval for first-in-human trial
6. New program targeting whole-person health care gets major grant
7. Targeting nicotine receptors to treat cognitive impairments in schizophrenia
8. Scientists announce new advance with potential for future cancer targeting
9. Investment in CRC screening targeting pre-medicare population could cut medicare treatment costs
10. Targeting hit-and-run cancer viruses
11. Targeting flight-or-fight hormone response to combat heart failure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... ... 24, 2017 , ... Dr. Ronald E. Hawkins, vice president ... of Peter A. Bell, DO, MBA, HPF, FACOEP-dist., FACEP, as the new dean ... Dr. Bell comes to Liberty from the Ohio University Heritage College of Osteopathic ...
(Date:2/24/2017)... ... February 24, 2017 , ... In the Health Care IT campaign, Robert Herjavec ... it’s not if you will be attacked, but when.” However, he and many others ... health care. , Improvements in auditing and monitoring have taken security in health care ...
(Date:2/24/2017)... Texas (PRWEB) , ... February 24, 2017 , ... ... to The Medical Center at Craig Ranch building at 8080 State Highway 121, Suite ... Medical District with easy access to Highway 121. , As the practice has grown, ...
(Date:2/24/2017)... ... , ... With ProGlass Prism users now have the ability to simulate prism ... position, rotation, distortion, edge softness, edge blur, chromatic aberration, individual glass position offset, anchor ... Prism users are given the tools and effects to generate a fractal prismatic ...
(Date:2/24/2017)... ... February 24, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at ... concerning this present generation. Yisrayl makes an astounding statement when he says that ... explains that the Bible details the current times so plainly that anyone should be ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... Research and Markets has announced the addition of the "Menopause Drugs ... ... Price Analysis and Strategies - 2016, provides drug pricing data and benchmarks ... What are the key drugs marketed for ... Menopause market? What are the unit prices and annual ...
(Date:2/23/2017)... Research and Markets has announced the addition ... 2016" report to their offering. ... The latest research Oesophageal Cancer Drugs Price ... in the global Oesophageal Cancer market. The research answers ... key drugs marketed for Oesophageal Cancer and their clinical attributes? How ...
(Date:2/23/2017)... Calif. , Feb. 23, 2017 ... company focused on the development and commercialization of ... pain, announced that it will release fourth quarter ... Thursday, March 2nd, 2017. AcelRx management will host ... Time (1:30 p.m. Pacific Time) on March 2 ...
Breaking Medicine Technology: