Navigation Links
Targeting oxidized cysteine through diet could reduce inflammation and lower disease risk
Date:3/27/2009

A team of scientists at Emory University School of Medicine has identified a direct link between oxidative stress and inflammatory signals in the blood. The finding could lead to improved strategies for preventing several diseases by including antioxidants in the diet and for reducing the impact of inflammation in critically ill patients by adding cysteine to intravenous or tube feeding.

The results are published online this week in the journal PLoS One.

Many normal metabolic functions produce reactive forms of oxygen that can damage cells. Oxidative stress, a disruption of the body's ability to control reactive forms of oxygen, has been connected with heart disease, diabetes and several neurodegenerative diseases.

However, scientists are still learning about the best ways to measure and reduce oxidative stress, says Dean P. Jones, PhD, professor of medicine and director of the Clinical Biomarkers Laboratory at Emory University School of Medicine. For example, large-scale clinical trials have shown little benefit in supplementing the diet with antioxidants such as vitamins C and E.

Jones and his colleagues, including Thomas R. Ziegler, MD of the Emory Department of Medicine, have been concentrating on a measure of oxidative stress in the blood: cysteine, an amino acid found in most proteins in the body. Cysteine can exist in two forms: oxidized and reduced. The higher the level of oxidative stress outside the cell, the more oxidized cysteine there is. Other indicators such as glutathione are more important inside cells.

Several studies have shown that levels of oxidized cysteine in the blood tend to rise as people age. Smoking and alcohol consumption are also linked with higher levels of oxidized cysteine. In addition, Jones and Ziegler have found that critical illness and malnutrition are associated with oxidative stress and oxidized cysteine in the blood.

Working with Jones, graduate student Smita
'/>"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Deadly in Pink: New Report Warns Big Tobacco Has Stepped Up Targeting of Women and Girls
2. Targeting the protein AEG1 impairs human liver cancer growth in mice
3. Tobacco Companies Targeting Teens, Study Says
4. APIC 2009 Targeting Zero Initiative Offers Practical Tools, Evidence-Based Elimination Strategies to Prevent the Deadliest Healthcare-Associated Infections
5. Targeting Cancers Own Stem Cells to Fight Recurrence
6. Researchers create smaller, brighter probe tailored for molecular imaging and tumor targeting
7. Health Care Service Corporation Finds Success With Innovative Program Targeting Obesity Epidemic
8. Peregrine Pharmaceuticals Awarded Broad New U.S. Patent for Anti-Viral Applications of Phospholipid-Targeting Antibodies
9. EGFR-targeting antibody licensed to Abbott
10. Tackling a hard-to-treat childhood cancer by targeting epigenetic changes
11. Tackling Hard-to-treat Childhood Cancer by Targeting Epigenetic Changes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... Move over antibiotic ointment, there might be a new salve ... from an unlikely placethe lowly salamander. Salamanders may not be ... and achieve amazing recovery of seriously damaged body parts. Now, ... The FASEB Journal , identifies a small ... may be the key to unlocking the secret of this ...
(Date:9/2/2014)... 2014In a new guideline, the Society for Maternal-Fetal Medicine ... in pregnancy. , "There is no evidence that ... of Delaware Center for Maternal and Fetal Medicine and ... is evidence that bed rest can be harmful for ... five women are placed on bed rest during their ...
(Date:9/2/2014)... Sept. 2, 2014 Cancer screening is a critical ... are often more treatable. But while there are already ... there is a great need for even more safe, ... , Now a team of researchers led by Shaoxin ... the potential of a new, non-invasive method to screen ...
(Date:9/2/2014)... 02, 2014 As an industry transformation expert, ... industry and predict change. Fortunately for him, that valuable skill ... identify markets that are eager for change — such as ... hearing aid market indicated it was ripe for better customer ... explained. As a result, he took matters into his own ...
(Date:9/2/2014)... in their work care for patients who are dying. ... that many nurses in training feel unprepared and anxious ... end-of-life care. , Scientists from the Sahlgrenska Academy have ... the University of Skvde and the Ersta Skndal University ... for dying patients, their ideas about how to support ...
Breaking Medicine News(10 mins):Health News:Salamander skin peptide promotes quick and effective wound healing in mice 2Health News:SMFM releases paper on activity restriction in pregnancy 2Health News:New method for non-invasive prostate cancer screening 2Health News:David Sapio Launches Zounds Hearing Franchise 2Health News:Many nurses unprepared to meet dying patients 2
... 28 The AFL-CIO Metal,Trades Department (MTD) ... the failure of the Energy Employees Occupational ... to nuclear,weapons workers and survivors victimized by ... work environment. MTD President Ron Ault charged ...
... PSI Corp. (Pink Sheets:,PSCP) is announcing that ... Signage Network, has signed additional facilities which will,utilize ... Chairman and CEO of PSI Corp. stated, "These ... to PSI,s network in,more than just additional revenue. ...
... along with weight, study finds , , MONDAY, April 28 ... the amount of food they could ingest not only lost ... according to a new report. , Thirty-eight morbidly obese ... reported that their pain decreased by an average of about ...
... social work faculty members have been chosen as the ... , a venture funded by the John A. ... of America , and directed by Dr. Barbara Berkman. ... opportunities for professional development and $100,000 in funding over ...
... INDIANAPOLIS Growing pains can mean one thing for ... teen with cerebral palsy attempting independence in an adult ... Medicine Center for Youth and Adults with Conditions of ... and live more independently. , IU pediatricians at ...
... LISLE, IL, April 28 /PRNewswire-FirstCall/ - SXC Health Solutions,Corp. ... SXC), a leading provider,of pharmacy benefits management services, announces ... that it has the leading competitive,bid to be considered ... Manager (PBM) contract., While there is no assurance ...
Cached Medicine News:Health News:Metal Trades Dept. Calls for Oversight Hearings Into Operations of Energy Employees Occupational Illness Compensation Program (EEOICP) 2Health News:Metal Trades Dept. Calls for Oversight Hearings Into Operations of Energy Employees Occupational Illness Compensation Program (EEOICP) 3Health News:Metal Trades Dept. Calls for Oversight Hearings Into Operations of Energy Employees Occupational Illness Compensation Program (EEOICP) 4Health News:PSI Corp. Announces Additional Hospitals and Medical Office Buildings to Utilize Its Digital Signage Network 2Health News:Gastric Bypass May Also Relieve Low Back Pain 2Health News:The Gerontological Society of america Announces 2008 Hartford Faculty Scholars 2Health News:Transitioning patients with pediatric disease to adulthood 2
(Date:9/2/2014)... , Sept. 2, 2014  Ameritox SM , the ... Deadly Trend: Prescription Drugs to Heroin," a research report ... heroin abuse, and examines deadly trends that have created ... here . The report is ... patients prescribed opioids. It examines five trends that distinguish ...
(Date:9/2/2014)... , September 2, 2014 ... by Transparency Market Research "Latin America Home Healthcare ... Therapeutic Home Healthcare Devices, Mobility Assist Devices and ... Respiratory Therapy, Infusion Therapy and Unskilled Home Healthcare ... and Forecast, 2014 - 2020" the Latin American ...
(Date:9/2/2014)... Sept. 2, 2014   Santa Clara dentist , ... special promotion for Invisalign. Invisalign is an orthodontic system ... It is often the orthodontic treatment of choice for ... aesthetics of it. For a limited time, patients can ... savings from the usual cost. This offer cannot be ...
Breaking Medicine Technology:Ameritox Research Report Reveals Pain Patients' Role in Current Heroin Epidemic 2Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 2Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 3Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 4Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 5Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 6Santa Clara Cosmetic Dentist, Dr. Alan Frame, is Now Offering a Special on Invisalign 2
... Oct. 29 , AT A GLANCE , ... PEM significantly improves ability to differentiate between benign ... MRI dramatically increased number of suspicious lesions found. ... women diagnosed with breast cancer found that Positron Emission ...
... Hospira, Inc. (NYSE: HSP ) celebrates the 25th anniversary ... 1984, Hospira,s PCA was the first pump of its kind, ... best when they are in pain, so allow them, within ... PCA technology has improved the safety and quality of care ...
Cached Medicine Technology:High-Resolution Breast PET Improves Breast Cancer Detection 2High-Resolution Breast PET Improves Breast Cancer Detection 3Healthcare Industry Celebrates 25 Years of Advanced Pain Management With PCA Infusion System 2Healthcare Industry Celebrates 25 Years of Advanced Pain Management With PCA Infusion System 3Healthcare Industry Celebrates 25 Years of Advanced Pain Management With PCA Infusion System 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: