Navigation Links
Targeting oxidized cysteine through diet could reduce inflammation and lower disease risk
Date:3/27/2009

A team of scientists at Emory University School of Medicine has identified a direct link between oxidative stress and inflammatory signals in the blood. The finding could lead to improved strategies for preventing several diseases by including antioxidants in the diet and for reducing the impact of inflammation in critically ill patients by adding cysteine to intravenous or tube feeding.

The results are published online this week in the journal PLoS One.

Many normal metabolic functions produce reactive forms of oxygen that can damage cells. Oxidative stress, a disruption of the body's ability to control reactive forms of oxygen, has been connected with heart disease, diabetes and several neurodegenerative diseases.

However, scientists are still learning about the best ways to measure and reduce oxidative stress, says Dean P. Jones, PhD, professor of medicine and director of the Clinical Biomarkers Laboratory at Emory University School of Medicine. For example, large-scale clinical trials have shown little benefit in supplementing the diet with antioxidants such as vitamins C and E.

Jones and his colleagues, including Thomas R. Ziegler, MD of the Emory Department of Medicine, have been concentrating on a measure of oxidative stress in the blood: cysteine, an amino acid found in most proteins in the body. Cysteine can exist in two forms: oxidized and reduced. The higher the level of oxidative stress outside the cell, the more oxidized cysteine there is. Other indicators such as glutathione are more important inside cells.

Several studies have shown that levels of oxidized cysteine in the blood tend to rise as people age. Smoking and alcohol consumption are also linked with higher levels of oxidized cysteine. In addition, Jones and Ziegler have found that critical illness and malnutrition are associated with oxidative stress and oxidized cysteine in the blood.

Working with Jones, graduate student Smita
'/>"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Deadly in Pink: New Report Warns Big Tobacco Has Stepped Up Targeting of Women and Girls
2. Targeting the protein AEG1 impairs human liver cancer growth in mice
3. Tobacco Companies Targeting Teens, Study Says
4. APIC 2009 Targeting Zero Initiative Offers Practical Tools, Evidence-Based Elimination Strategies to Prevent the Deadliest Healthcare-Associated Infections
5. Targeting Cancers Own Stem Cells to Fight Recurrence
6. Researchers create smaller, brighter probe tailored for molecular imaging and tumor targeting
7. Health Care Service Corporation Finds Success With Innovative Program Targeting Obesity Epidemic
8. Peregrine Pharmaceuticals Awarded Broad New U.S. Patent for Anti-Viral Applications of Phospholipid-Targeting Antibodies
9. EGFR-targeting antibody licensed to Abbott
10. Tackling a hard-to-treat childhood cancer by targeting epigenetic changes
11. Tackling Hard-to-treat Childhood Cancer by Targeting Epigenetic Changes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... A decreased ability to identify odors might indicate ... while examinations of the eye could indicate the ... in the brain, according to the results of ... Association International Conference 2014 (AAIC 2014) in Copenhagen. ... ability to identify odors was significantly associated with ...
(Date:7/13/2014)... 2014 Celebrity fitness trainer and former ... promotional partnership with Aqua Health Labs for their flagship ... supplement . The collaboration was recently announced live on ... trainer , actor, model, and a two time World ... celebrities, he has prepared stars including Demi Moore, Hilary ...
(Date:7/13/2014)... 13, 2014 According to The Peripheral ... a comprehensive program that teaches people how to deal ... without medications. This program also provides people with ... peripheral neuropathy , including numbness, prickling, burning, and intense ... that this home treatment program can help people eliminate ...
(Date:7/12/2014)... (PRWEB) July 13, 2014 Recently, Fadhits.com, a ... collection of elegant long graduation dresses to its ... promotion for its loyal clients. It wants to bring more ... items are now offered at discounted prices, up to 72% ... company is always working hard. Its online shop is a ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Fresh off their ... Colombia will meet on September 5th at Sun Life ... world to see some of the brightest stars in the ... fans in Miami will be treated to some of the ... is currently ranked as the third best team in the ...
Breaking Medicine News(10 mins):Health News:Smell and eye tests show potential to detect Alzheimer's early 2Health News:Smell and eye tests show potential to detect Alzheimer's early 3Health News:Smell and eye tests show potential to detect Alzheimer's early 4Health News:Smell and eye tests show potential to detect Alzheimer's early 5Health News:Smell and eye tests show potential to detect Alzheimer's early 6Health News:Smell and eye tests show potential to detect Alzheimer's early 7Health News:Celebrity Fitness Expert Supports Revolutionary New Health Supplement 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 3Health News:New Collection of Long Graduation Dresses Revealed by Fadhits.com 2Health News:Brazil Vs. Colombia Tickets Sun Life Stadium: Ticket Down Slashes Ticket Prices for Friendly Match Between Colombia and Brazil 2Health News:Brazil Vs. Colombia Tickets Sun Life Stadium: Ticket Down Slashes Ticket Prices for Friendly Match Between Colombia and Brazil 3
... Surgical Company,(Nasdaq: STAA ) today announced ... CAST (Collamer(R) Accommodating Study Team), to work with ... accommodative properties,of its Collamer lens technology. Accommodating Intraocular ... eye,s ability to "accommodate," or,to adjust to see ...
... of American Pathologists (CAP), a deemed accreditation authority, ... CAP 15189(SM) Accreditation to Piedmont Medical Laboratory ... International Organization for Standardization (ISO) for laboratory technical ... improved patient safety and risk reduction, outlining standards ...
... Mass., Nov. 20 Does your pet misbehave when,you ... the,holidays, the change in schedule can negatively affect your ... pets in the United States,suffer from separation anxiety, resulting ... (Photo: http://www.newscom.com/cgi-bin/prnh/20081120/NYFNSR09 ) , ...
... an easy,fun and inexpensive way to stay fit have ... Vol.2 ( www.kideosyncrasy.com ) is a fun tool for,teaching ... jam-packed with live-action;,kids-teaching-kids how to easily step into fun ... on nutrition and exercise, Kideosyncrasy,promotes health and fitness in ...
... and Christine Whitelaw, M.D. demonstrate laser hair removal on the ... ... Utah (Vocus) November 20, 2008 -- With laser technology, beauty has become ... commonplace: an essential accessory in the medi-spa, offering a range of cosmetic ...
... Center, proudly announces its surgical center is "infection free" ... 2,000 procedures have been performed, according to Dr. ... outpatient specialty hospital has taken a variety of proactive ... instituting very stringent protocols and procedures to ensure the ...
Cached Medicine News:Health News:STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses 2Health News:STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses 3Health News:STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses 4Health News:STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses 5Health News:Accreditation to the International Standards Organization for Quality Management Granted to First U.S. Lab 2Health News:Accreditation to the International Standards Organization for Quality Management Granted to First U.S. Lab 3Health News:A Happy Pet for the Holidays: Natural Remedies to Treat Animals' Complex Emotions 2Health News:Give Kids the Gift of Fun and Fitness This Holiday Season 2Health News:Laser Beam Beauty: 'The Complete Guide to Laser Hair Removal' DVD released by Aesthetic VideoSource 2Health News:Zero MRSA or Patient Infections Reported After Two Years as D.I.S.C. Sports and Spine Center Sets New Standard for Specialty Hospitals 2Health News:Zero MRSA or Patient Infections Reported After Two Years as D.I.S.C. Sports and Spine Center Sets New Standard for Specialty Hospitals 3Health News:Zero MRSA or Patient Infections Reported After Two Years as D.I.S.C. Sports and Spine Center Sets New Standard for Specialty Hospitals 4
(Date:7/10/2014)... , July 10, 2014 Integrated Silicon Solution, ... advanced memory and analog IC solutions, today announced that ... July 24, 2014, at 7:00 a.m. Pacific Time (10:00 ... for the fiscal 2014 third quarter ended June 30, ... telephone, dial 1-888-556-4997 before 6:50 a.m. Pacific time on ...
(Date:7/10/2014)... 10, 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... has completed the sale to Galderma of all rights ... held by Valeant for $1.4 billion in cash, pursuant ... recently completed its acquisition of Galderma. ... products to a company that is firmly committed to ...
(Date:7/10/2014)... , July 10, 2014 CVS Caremark Corporation ... of directors has approved a quarterly dividend of $0.275 (27.5 ... is payable on August 1, 2014, to holders of record ... CVS Caremark is dedicated to helping people on ... company in the United States . Through ...
Breaking Medicine Technology:
... 11 Bayer HealthCare Pharmaceuticals announced today that ... U.S. Food and Drug Administration (FDA) for ciprofloxacin dry ... to Pseudomonas aeruginosa in cystic fibrosis (CF) patients. A ... Medicines Agency. Ciprofloxacin DPI is an investigational drug–device combination ...
... Zimmer Holdings, Inc. (NYSE: ZMH ; ... recently introduced Continuum Acetabular Cup System at the ... Continuum Cup combines the best ... Technology, Metasul ® Metal-on-Metal technology, BIOLOX ® delta ...
Cached Medicine Technology:FDA Grants Bayer HealthCare Pharmaceuticals Orphan Drug Designation for Investigational Ciprofloxacin Dry Powder Inhaler for the Treatment of Cystic Fibrosis 2FDA Grants Bayer HealthCare Pharmaceuticals Orphan Drug Designation for Investigational Ciprofloxacin Dry Powder Inhaler for the Treatment of Cystic Fibrosis 3FDA Grants Bayer HealthCare Pharmaceuticals Orphan Drug Designation for Investigational Ciprofloxacin Dry Powder Inhaler for the Treatment of Cystic Fibrosis 4FDA Grants Bayer HealthCare Pharmaceuticals Orphan Drug Designation for Investigational Ciprofloxacin Dry Powder Inhaler for the Treatment of Cystic Fibrosis 5FDA Grants Bayer HealthCare Pharmaceuticals Orphan Drug Designation for Investigational Ciprofloxacin Dry Powder Inhaler for the Treatment of Cystic Fibrosis 6FDA Grants Bayer HealthCare Pharmaceuticals Orphan Drug Designation for Investigational Ciprofloxacin Dry Powder Inhaler for the Treatment of Cystic Fibrosis 7FDA Grants Bayer HealthCare Pharmaceuticals Orphan Drug Designation for Investigational Ciprofloxacin Dry Powder Inhaler for the Treatment of Cystic Fibrosis 8New Hip Implant Provides Personalized Fit 2New Hip Implant Provides Personalized Fit 3New Hip Implant Provides Personalized Fit 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: