Navigation Links
Targeting Cancer's Own Stem Cells to Fight Recurrence
Date:1/21/2009

In the lab, scientists used a virus to thwart tumor's comeback

WEDNESDAY, Jan. 21 (HealthDay News) -- Scientists have located a group of cancer stem cells or "tumor-initiating cells" which, when targeted with a reprogrammed herpes virus, are prevented from turning malignant.

The finding bolsters the theory that cancer harbors its own secret cache of stem cells that are resistant to conventional therapies and responsible for tumor re-emergence.

Eliminating these malingerers could be key in the fight against certain cancers, such as neuroblastoma, which was the focus of this study.

"This research and this line of research in general is very exciting," added Dr. L. Gerard Toussaint III, an assistant professor of neuroscience and experimental therapeutics at Texas A&M Health Science Center College of Medicine and a neurosurgeon with the Texas Brain and Spine Institute in Bryan. "Their approach is to genetically engineer a virus that would only be turned on in the stem cell population."

This type of virus-against-cancer therapy may be the next generation of anti-cancer treatments, he said.

The study was published online Jan. 21 in the journal PLoS (Public Library of Science) One.

Neuroblastomas, which develop in the nerve tissue of the adrenal gland, neck, chest or spinal cord, account for 8 percent to 10 percent of childhood cancers, the report stated. Remission is common, but so is relapse, and long-term survival in high-risk cases is less than 50 percent.

"The cancer often responds to chemotherapy and more often than not will shrink but too often it comes back," explained Dr. Jeffrey Toretsky, an associate professor of oncology and pediatrics at Georgetown's Lombardi Comprehensive Cancer Center in Washington, D.C. "The promise is that they will be able to successfully create some agent, a virus, that would be able to get at the cells responsible for regrowth."


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Investigational Agent Targeting Metabotropic Glutamate 2/3 Receptors Demonstrates Antipsychotic Activity in Humans, Study in Nature Medicine Finds
2. Chronic infection persists by targeting stromal cell network in lymphoid organs
3. Prime Access Creates Groundbreaking Ads Targeting Urban Teens for the White Houses National Youth Anti-Drug Media Campaign
4. Isis Adds New Drug to Its Development Pipeline: ISIS 388626 Targeting SGLT2 for the Treatment of Type 2 Diabetes
5. Phase I pharmacokinetic study of ECO-4601, a novel bifunctional targeting agent
6. Anticancer Drugs Targeting the ErbB (EGFr/HEr2) Pathway Alone Generated Global Sales of Nearly $5 Billion in the First Nine Months of 2007
7. Tobacco marketers targeting teens near schools
8. APIC launches Targeting Zero initiative to eradicate infections deemed preventable by CMS
9. New Research Shows Nutrition Programs Targeting Pregnancy and First 24 Months of Life Dramatically Improve Child Survival and Overall Health
10. Targeting gut bugs could revolutionize future drugs, say researcher
11. Targeting astrocytes slows disease progression in ALS
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Targeting Cancer's Own Stem Cells to Fight Recurrence
(Date:11/27/2014)... By Randy Dotinga ... -- Some people,s brains seem pre-wired to acquire a second ... beyond their mother tongue will likely gain a brain boost, ... connected and integrated after learning," said study co-author Ping Li, ... Pennsylvania State University. But it,s even more interesting, Li said, ...
(Date:11/27/2014)... November 27, 2014 In order to enable ... Sharpes, Fla., designed an easy way to avoid touching a ... He then created a prototype of the patent-pending Toilet Tamer, ... a toilet seat and/or lid in a more sanitary manner. ... spread of germs. Overall, it promotes good hygiene and peace ...
(Date:11/27/2014)... November 27, 2014 Tylenol lawsuits ( ... allegedly injured by the medication are continuing to move ... is looking ahead to a status conference in December, ... Scheduling Order issued earlier this year, a conference in ... at 10:00 a.m. Items likely to be discussed at ...
(Date:11/27/2014)... “LAB.C” was featured on NewsWatch as part ... coolest technology products available to consumers. Mallory Sofastaii, a technology ... and shared with viewers the company offers a cable ... , Consumers love portability and functionality. A unique mobile ... the iPhone5 and 5S has a portable USB charger built ...
(Date:11/27/2014)... (PRWEB) November 27, 2014 HealthPostures, ... office ergonomics equipment , has announced that it ... Commercial Office Environments. The partnership will put HealthPostures' ... furnishings location. , In addition to having its ... dealer partnership promotes HealthPostures' products with the business ...
Breaking Medicine News(10 mins):Health News:Some People May Be Pre-Wired to Be Bilingual 2Health News:Some People May Be Pre-Wired to Be Bilingual 3Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 3Health News:Top Mobile Friendly Accessories were Featured on NewsWatch Television on October 30, 2014 2Health News:Ergonomics Manufacturer Announces New Partnership with Office Supply Dealer 2
... the number of seats in existing facilities to fill the ... the central government's proposed quota policy, says Chief Minister Arjun ... medical institutions and open more institutes in the state," said ... doctors and this was the only to "adjust the numbers". ...
... mosquito-transmitted viral fever, has claimed 12 lives in Betul district ... more districts//. ,'With three more deaths Sunday - two ... number of deaths allegedly due to Chikangunya fever in Betul ... here said Thursday. ,'The dead include a 10-year-old ...
... peripheral artery disease (PAD) patients have showed lesser death ... ,Researchers have also indicated that less physically active ... ,‘We found that there is a survival ... active in their daily routines,’ said Mary M. McDermott, ...
... can cause developmental delays in infants whose mothers were ... banned in the United States, officials in Africa plan ... malaria. ,According to study author Brenda Eskenazi, a ... the University of California, Berkeley, the potential benefits of ...
... that vaccines that contain mercury do not increase ... scientists examined patterns between the developmental disorder and ... in the journal Pediatrics. ,Their research ... children given shots after thimerosal, a mercury-based preservative, ...
... the All India Institute of Medical Sciences remained crippled ... to protest the move to sack its Director P ... were closed since last evening as resident doctors and ... apex body headed by Union Health Minister A Ramadoss ...
Cached Medicine News:Health News:Chikungunya Death Toll Raises to 12 in Madhya Pradesh 2Health News:Physical Activity benefited Peripheral Artery Disease (PAD) patients 2Health News:Developmental Delays in Infants Linked to DDT 2
(Date:11/26/2014)... Colo. , Nov. 25, 2014   Heska Corporation ... "Heska" or the "Company"), a provider of advanced veterinary ... Robert Grieve , Executive Chair, will attend The Benchmark ... 2014. The one-on-one conference will be held at The Palmer ... from 8 a.m. to 2:30 p.m. Please email ...
(Date:11/26/2014)... , Nov. 25, 2014  Array ... today announced that its Chief Executive Officer, ... the following upcoming conferences.  The public is ... webcasts on the Array BioPharma website:  ... 3, 2014Time:1:30 p.m.  Eastern Time Location: Palace ...
(Date:11/26/2014)... LONDON , Nov. 25, 2014 ... AZN ) today announced that AMAGINE-2 TM , a ... in more than 1,800 patients with moderate-to-severe plaque psoriasis, met ... (ustekinumab) and placebo at week 12. Brodalumab 210 mg given ... each shown to be superior to Stelara on the primary ...
Breaking Medicine Technology:Heska to Attend Benchmark Micro Cap Discovery Conference 2Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 2Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 3Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 4Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 5Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 6Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 7Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 8Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 9Amgen And AstraZeneca Announce Positive Results From Third And Final Pivotal Phase 3 Study Of Brodalumab In Patients With Moderate-To-Severe Plaque Psoriasis 10
... SEOUL, South Korea, Dec. 5, 2011 /PRNewswire-Asia/ -- The ... Industry Development Institute announced that the Health Authority-Abu Dhabi ... National University Hospital, Asian Medical Center and Seoul St. ... a patient treatment-reference system in Abu Dhabi, on Nov. ...
... BEIJING, Dec. 5, 2011 /PRNewswire-Asia/ -- GC-Rise Pharmaceutical Co. ... holds a majority stake, was recently listed as one ... companies which rides on high growth over the past ... women,s health in China, saw its operating revenues rising ...
Cached Medicine Technology:South Korea Signs Accord with Abu Dhabi Health Authority on Hospital Service Agreement 2Women Health Expert GC-Rise Listed in Deloitte's 50 Top-performing Companies 2
... This stool is unquestionably the finest operating ... especially for the ophthalmic surgeon who must ... A poor stool can unexpectedly shift resulting in ... solid base of five sturdy casters. A "foot ...
This is a 2.5x focusing Galilean telescope with a range from 70cm to infinity. Ideal for use at sporting events, as well as for a wide range of hobbies....
This 6x or 8x aspheric magnifier is fitted with a distance piece and is particularly useful for patients with tremor or focusing difficulties. The magnifier can be either spectacle mounted or hand h...
All Keeler magnifiers and telescope are available on a clip to fit over the patient's own spectacle...
Medicine Products: