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Targeted radiation therapy minimizes GI side effects for prostate cancer patients, Penn study shows
Date:10/26/2010

on for men choosing among the various treatment options for the disease, which include observation, radiation, surgery, chemotherapy and hormonal therapies.

Using a Medicare database of men across the United States, Bekelman's team studied 12,598 men 65 years and older who were diagnosed with non-metastatic prostate cancer between 2002 and 2004. The authors followed the patients through 2006 and identified complications that were serious enough to require invasive procedures (including surgeries) and/or hospitalization. The findings revealed that among men who received IMRT, 18.8 percent had serious bowel complications during the two years after their treatment, compared to 22.5 percent of men treated with CRT. (Since specifics about each patient's case could not be accounted for in the database, the authors note that some of the complications identified may have been caused by factors other than radiation treatment.) The researchers found no substantial difference in incidence of urinary or sexual side effects such as erectile dysfunction, but Bekelman notes that since the study was limited to complications involving invasive surgical procedures, it may not capture the true prevalence of sexual side effects following treatment, for which patients may have sought less invasive remedies.


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Contact: Holly Auer
holly.auer@uphs.upenn.edu
215-349-5659
University of Pennsylvania School of Medicine
Source:Eurekalert

Page: 1 2

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