Navigation Links
Targeted radiation therapy can control limited cancer spread
Date:8/12/2008

rsity of Chicago has directed since 2005,.

Patients with stage-IV cancer with one to five distant metastases and no tumors bigger than 10 centimeters (about four inches) in diameter were eligible to participate in the study either before or after chemotherapy treatment.

Each patient received three doses, separated by at least two days, of precisely targeted radiation therapy focused on each metastatic tumor. Treatment was usually completed within one week. The first patients in the study received lower doses. As few side effects were seen, radiation doses were gradually increased in subsequent groups of patients.

"Previous studies determined the maximal radiotherapy doses for single organs," said Salama, lead author of the study, "but this technique has not been tested for simultaneous use on multiple organs. So we designed a dose-escalation trial to determine the optimal dose, starting with fairly low levels and increasing the dose in later groups of patients."

From November 2004 through February 2008, 29 patients, with a total of 56 cancerous lesions, enrolled in the trial. Of the 29 patients, 24 had progressed after at least one round of systemic chemotherapy. For the other five, there was no promising choice of therapy.

Six of the 29 initial patients had lasting tumor control, with no detectable evidence of disease 15 months after treatment.

Many patients had a complete response in at least one tumor. Thirty-one of the 56 treated tumors (55%) completely disappeared. Two tumors (4%) had a partial response, defined as reduction in tumor volume of more than 30 percent. Only three of the 56 tumors progressed (5%), growing in size by 20 percent or more during the treatment phase.

Tumor control improved as the radiation dose increased. Thirty-nine percent of the 31 tumors treated with 24 gray of radiation met the criteria for tumor control--a complete or partial response. That increased to 79 percent for
'/>"/>

Contact: John Easton
john.easton@uchospitals.edu
773-702-6241
University of Chicago Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Targeted drug therapy found effective in patients with common form of immune-mediated kidney disease
2. Personalizing medicine: New research shows potential of targeted therapies for cancer
3. Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive Imaging of Patient and Tumor Status Will Determine Clinical and Commercial Success
4. Kiss One-Size-Fits-None Goodbye: Archi-Tech Systems Offers First SFA Solution Targeted to Pharmaceutical Sales Organizations
5. Let Water Be Water, LLC, Launches WAT-AAH!(TM), First Premium Brand of Pure Water with Function Specially Targeted to Kids and Teens
6. Targeted therapy plus chemotherapy may pack 1-2 punch against melanoma
7. Penn researchers find targeted therapy combination overcomes treatment resistance in liver cancer
8. PETs targeted imaging may lead to earlier diagnosis of dementia and Alzheimers disease
9. New study of targeted therapies for breast cancer -- model for global clinical trials
10. NeoStrata Clinical Findings Reveal Benefits of Combining Glycolic Acid Peels and Targeted Home Care With Microdermabrasion for Optimized Treatment of Photodamaged Skin
11. A major step toward a more targeted treatment for auto-immune diseases?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... Best Cheap Hosting USA is among the ... has recently announced that iPower ( http://www.best-cheap-hosting-usa.com/go/iPower/ ) is ... around the world. , “iPower is one of the ... providing various kinds of useful products for new and ... excellent customer service and a number of features which ...
(Date:10/22/2014)... Although there are only 24 hours in a day, that doesn’t ... finding time within their busy schedules for exercise and fitness. Fortunately, ... to get in shape. Here are five ways you can reach ... Change Up Your Commute , Consider riding a bike or taking ... your daily routine. If you must use your car to get ...
(Date:10/22/2014)... WALTHAM, MA (PRWEB) October 22, 2014 ... developing new solutions for the treatment of bacterial infections, ... J. Sinskey has joined its board of directors. ... Microbiology and Engineering Systems at The Massachusetts Institute of ... the MIT faculty since 1968. Dr. Sinskey also holds ...
(Date:10/22/2014)... -- Two sisters in high school have developed ways ... Medha Krishen use electronic stethoscopes, which electronically amplify body ... patterns or heartbeats. Ilina, a senior at Port ... a way to detect early lung damage in people ... Ilina recorded one breath cycle each from 16 smokers, ...
(Date:10/22/2014)... Oct. 21, 2014 (HealthDay News) -- Measures taken by ... in Ebola-ravaged Liberia may have limited the spread of ... report. The Firestone Natural Rubber Co. provides health ... residents of nearby densely populated communities. Between Aug. ... suspected Ebola cases among those 80,000 people. That incidence ...
Breaking Medicine News(10 mins):Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:HealthGuideMD Presents Ways to Improve Your Exercise and Fitness 2Health News:Akeso Biomedical Appoints Dr. Anthony J. Sinskey to Board of Directors 2Health News:Teen Sisters Develop Ways to Measure Lung, Heart Damage 2Health News:Tire Company Sets Standard for Ebola Care in Liberia: CDC 2
... ... has joined the Climate Savers Computing Initiative, a non-profit organization dedicated to reducing computer power ... ... that it has joined the Climate Savers Computing Initiative, a non-profit organization dedicated to reducing ...
... ... few short months ago the Pionetics Corporation introduced the LINX® Water Treatment System, the smartest ... so well, the company just shipped its 1,000th unit., , ... San Carlos, CA (PRWEB) June 25, 2010 -- Just a ...
... red wine, grapes, blueberries, peanuts and other plants ... to vision researchers at Washington University School of Medicine ... preserving vision in blinding eye diseases such as diabetic ... blindness in Americans over 50. The formation of ...
... ... Bob Adams speaks out for drug awareness and education. , , ... Los Angeles (Vocus) June 26, 2010 -- Addressing a ... Church of Scientology Community Relations Specialist, Bob Adams asked the youth who among them ...
... , ... announce that Asia Research News 2010 is now available online and in print. , ... (PRWebUK) June 24, 2010 -- We ... online at Asia Research News , , , , ,The magazine features interesting on-going ...
... experienced the strong heartbeat that accompanies emotions such as fear ... emotions be used to combat heart failure? Results of a ... present a strong case. In the ... that two experimental drugs have the potential to restore pumping ...
Cached Medicine News:Health News:Be Green Canada Joins Computing Initiative 2Health News:Be Green Canada Joins Computing Initiative 3Health News:Pionetics Ships its 1,000th LINX Drinking Water System 2Health News:Pionetics Ships its 1,000th LINX Drinking Water System 3Health News:Ingredient in red wine may prevent some blinding diseases 2Health News:Ingredient in red wine may prevent some blinding diseases 3Health News:Young Athletes Warned of Drug Dangers 2Health News:Young Athletes Warned of Drug Dangers 3Health News:Asia Research News 2010 2Health News:Asia Research News 2010 3Health News:Targeting flight-or-fight hormone response to combat heart failure 2Health News:Targeting flight-or-fight hormone response to combat heart failure 3
(Date:10/22/2014)... -- InVivo Therapeutics Holdings Corp. (OTCQB: NVIV) based in ... cord injury (SCI) treatment with their novel Neuro-Spinal Scaffold. ... regrowth in the spinal cord area when cells are ... polymer, the scaffold ultimately breaks down to water and ... NVIV has recently attracted significant investor attention with the ...
(Date:10/22/2014)... , Oct. 22, 2014 WHEN: Wednesday, October ... complimentary registration available at: http://bit.ly/1yStiU9 ... Vidyasekar and Visionary Innovation Research Group Senior ... electricity, self-assembling materials, nanobots and flexible electronics ... will transform our lives in the coming ...
(Date:10/22/2014)... 22, 2014 Provectus Biopharmaceuticals, Inc. (NYSEMKT: PVCT) ... novel investigational drug for cancer, is designed for injection ... effects. Its oncology focus is on melanoma, breast cancer ... 2 trials of PV-10 as a therapy for metastatic ... atopic dermatitis and psoriasis. This summer, ...
Breaking Medicine Technology:InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 2InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 3Futuristic Technologies That Will Transform Our World Beyond 2030 2Futuristic Technologies That Will Transform Our World Beyond 2030 3Futuristic Technologies That Will Transform Our World Beyond 2030 4Provectus Biopharmaceuticals Looks at the Asian Markets: Analyst Coverage by Small Cap Traders 2
... 24, 2012 /PRNewswire-Asia/ -- China Kanghui Holdings (NYSE: ... manufacturer and marketer of orthopedic implants in China, today announced ... First Quarter 2012 Highlights , ... by 21.6% year-over-year to RMB82.7 million from RMB68.0 ...
... Uroplasty, Inc. (NASDAQ: UPI ), a medical ... products for the treatment of patients with voiding dysfunctions, ... expand its commitment to using the Company,s neuromodulation technology ... begin development of an implantable tibial nerve stimulator for ...
Cached Medicine Technology:China Kanghui Holdings Reports First Quarter 2012 Financial Results 2China Kanghui Holdings Reports First Quarter 2012 Financial Results 3China Kanghui Holdings Reports First Quarter 2012 Financial Results 4China Kanghui Holdings Reports First Quarter 2012 Financial Results 5China Kanghui Holdings Reports First Quarter 2012 Financial Results 6China Kanghui Holdings Reports First Quarter 2012 Financial Results 7China Kanghui Holdings Reports First Quarter 2012 Financial Results 8China Kanghui Holdings Reports First Quarter 2012 Financial Results 9China Kanghui Holdings Reports First Quarter 2012 Financial Results 10China Kanghui Holdings Reports First Quarter 2012 Financial Results 11China Kanghui Holdings Reports First Quarter 2012 Financial Results 12China Kanghui Holdings Reports First Quarter 2012 Financial Results 13Uroplasty Announces Product Development and New Clinical Trial Initiatives 2Uroplasty Announces Product Development and New Clinical Trial Initiatives 3Uroplasty Announces Product Development and New Clinical Trial Initiatives 4