Navigation Links
Tamoxifen Speeds Diagnosis of ER-Negative Breast Cancer
Date:10/7/2008

Study suggests the drug may make tumors easier to spot

TUESDAY, Oct. 7 (HealthDay News) -- A treatment that helps prevent one type of breast cancer in women with an evaluated risk of the disease also appears to help doctors make an earlier diagnosis of another form of breast cancer, a new study reports.

Tamoxifen previously had been shown to reduce the risk of estrogen receptor (ER) positive breast cancer in women at high risk of the disease, but not to affect the chance of developing ER-negative disease.

However, the study by researchers at the University of Texas M.D. Anderson Cancer Center in Houston found that the treatment helped doctors diagnosis women who later developed estrogen receptor (ER) negative breast cancer an average of one year sooner than the same at-risk patients who instead took a placebo.

For the study, 13,388 women at high risk of breast cancer participated in the trial; 174 women were diagnosed with ER-positive tumors and 69 women with ER-negative tumors. The median time to diagnosis for ER-negative disease was 36 months in the placebo group but only 24 months in the tamoxifen group.

The median time to diagnosis for ER-positive disease was similar in the placebo and tamoxifen groups at 43 and 51 months, respectively, which is not statistically different.

It's not clear why the diagnosis time of ER-negative tumors is so different, but the authors hypothesized that the drug may make the tumors more detectable. No evidence was found that tamoxifen altered the growth rate of ER-negative disease.

The study was published online Oct. 7 in the Journal of the National Cancer Institute.

The findings should be investigated further, the researchers concluded.

More information

The National Cancer Institute has more about tamoxifen.



-- Kevin McKeever



SOURCE: Journal of the National Cancer Institute, news release, Oct. 7, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Future hope for patients with breast cancers resistant to tamoxifen
2. New Molecule Discovery Shows Promise Against Tamoxifen-Resistant Breast Cancers
3. Acupuncture relieves hot flushes in breast cancer patients taking tamoxifen
4. Moving beyond tamoxifen: Drug discovery and the future of selective hormone receptor modulators
5. Chemotherapy and tamoxifen reduce risk of second breast cancer
6. Data Show ARIMIDEX(R) (Anastrozole) Continues To Be Superior to Tamoxifen in Helping Reduce the Risk of Recurrence in Patients With Early Breast Cancer
7. Arimidex Beats Tamoxifen in Keeping Breast Cancer at Bay
8. Tamoxifen Helps Treat Bipolar Disorder
9. New Technology Speeds GI Disease Diagnosis
10. Fujifilm Receives FDA Approval for Unity SpeedSuite(TM)
11. DDT Compound Speeds Breast Cancer Growth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2017)... ... April 25, 2017 , ... Vetoquinol USA® , a ... UCII, part of the EQUISTRO line, at this week’s Rolex Kentucky Three-Day Event ... the immunologic level. , The scientifically-developed Flexadin UCII supports the body’s normal repair ...
(Date:4/24/2017)... ... April 24, 2017 , ... Michael Vick announced his ... the quarterback position. The former overall number one pick in the 2001 NFL Draft, ... He holds the record for the most career rushing yards by a quarterback (6,109) ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... ... Educational Research Association’s Outstanding Public Communication of Education Research Award. The award honors ... including education communities. It recognizes a scholar who has demonstrated the capacity to ...
(Date:4/24/2017)... ... , ... Sean Fay is the undisputed king of the infomercial. With clients ... George Foreman Grill (which sold more than 100 million units worldwide), he has created ... Now, due to changes in the broadcast media landscape, the once ever-present infomercial has ...
(Date:4/24/2017)... McLean, Virginia (PRWEB) , ... April 24, 2017 ... ... have announced that they are seeking public support to bring their novel lifesaving ... in appearance, wearable device packed with medical-grade sensors, specially designed to read a ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017  AbbVie (NYSE: ... 99 percent (n=145/146) of chronic hepatitis C virus ... 5 or 6 and compensated cirrhosis (Child-Pugh A) ... (SVR 12 ) with its investigational, pan-genotypic regimen ... rates were seen following 12 weeks of G/P ...
(Date:4/20/2017)... 20, 2017 Eyevensys, a private ... non-viral gene expression technology that enables the safe, local, ... address a wide range of ophthalmic diseases, announces it ... products Regulatory Agency (MHRA) to advance its technology into ... ...
(Date:4/20/2017)... Research and Markets has announced the addition of ... By Service (Manufacturing, Research), By Country, (Brazil, Mexico, Colombia, Argentina, ... to their offering. ... The Latin American pharmaceutical contract manufacturing services market is anticipated ... drug registration cost in Latin American countries and continuous economic ...
Breaking Medicine Technology: