Navigation Links
Tamoxifen May Offer Long-Term Heart, Cancer Protection
Date:3/22/2011

By Kathleen Doheny
HealthDay Reporter

TUESDAY, March 22 (HealthDay News) -- Taking the breast cancer drug tamoxifen for the recommended five years protects women from breast cancer recurrence better than a two-year course of the drug and it also shields some women from cardiovascular disease, new research finds.

The cancer protection and heart-disease risk reduction were noted 15 years after starting treatment, according to the study published online March 21 in the Journal of Clinical Oncology.

The findings may surprise many women on the medication, said Allan Hackshaw, deputy director of Cancer Research and the University College London Cancer Trials Center. "I think many women don't realize the benefits [reduced cancer recurrence] last a long time if they can complete the five-year course, and particularly also the CV [cardiovascular] disease benefit," he said.

Hackshaw and his colleagues studied follow-up data for 3,449 participants in the Cancer Research UK "Over 50s" trial comparing tamoxifen use of five years and two years by women with early beast cancer. The women were between 50 and 81 at the start.

During the initial study period, 1987 to 1997, the women took 20 milligrams of tamoxifen a day for two years. After that, they were assigned randomly to stop taking the drug or to continue taking tamoxifen for three more years, if they were recurrence-free.

The researchers then tracked cancer recurrences, new tumors, death and cardiovascular events through April 2010.

There were 1,103 recurrences, 755 deaths from breast cancer, 621 cardiovascular events and 236 deaths from cardiovascular events. They found that 15 years after the women first began taking tamoxifen, for every 100 who took it for five years, nearly six fewer women suffered a recurrence compared to those on the two-year regimen.

The longer treatment reduced the risk of breast cancer developing in the opposite bre
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Breast Cancer Drug Tamoxifen Saves Lives, Medical Costs: Study
2. Taking tamoxifen to prevent breast cancer can save lives and money
3. HOXB7 gene promotes tamoxifen resistance
4. Cough medicine could help doctors identify how breast cancer patients metabolize tamoxifen
5. Scientists reprogram triple-negative breast cancer cells to respond to tamoxifen
6. Gene Mutation Offers Clues to Tamoxifen-Blood Clot Link
7. Gene mutation increases thromboembolism risk in women taking tamoxifen
8. Cell study finds receptor can fight tamoxifen-resistant breast cancer cells
9. Raloxifene, Tamoxifen Both Guard Against Breast Cancer
10. Doctors must collaborate so that patients get full benefit of tamoxifen treatment
11. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tamoxifen May Offer Long-Term Heart, Cancer Protection
(Date:1/22/2015)... City, Florida (PRWEB) January 22, 2015 IsoComforter, ... cold therapy machine with patented IsoTube design to treat specific ... has introduced the most progressive and easy to use patented ... treat post-operative and sports related orthopedic and muscle injuries. ...
(Date:1/22/2015)... Payday lending practices in four southern states ... distress to the states that permit them, according to ... on Race and Wealth. , While they generate hundreds ... at the same time substantially depress economic activity, according ...
(Date:1/22/2015)... 2015 As interest in the value of ... momentum worldwide, Rev. Eric J. Hall , president and ... (HCCN), will be the keynote speaker on January 27 at ... health system. , The conference, “Hope and Resilience: Innovative and ...
(Date:1/22/2015)... Compare-autoinsurance.org has released a new blog post presenting a ... insurance policy . , Some types of vehicles cannot be ... newly released blog post to see if their vehicle qualifies for ... are some of the cars that cannot be covered by a ...
(Date:1/22/2015)... 22, 2015 Step into a macabre ... Science Museum of Virginia. Wicked Plants, the Museum’s latest ... unearths 75 poisonous, carnivorous and diabolical plants inside of ... to uncover the biochemical, physical and neurological processes between ...
Breaking Medicine News(10 mins):Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Some Vehicles Cannot Be Covered By An Auto Insurance Policy! 2Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... “Hi, who’s on ... tone in her voice. A caller named Mary Ellen describes “very swollen legs from ... Maggie McDermott, RN, deadpans in her Irish brogue. “Now Magster, let’s not start right ... ...
... Key ... , ... 19, 2009 -- Key Metric Software has released Duplicate File Detective v3.0, a major ... a number of new features that focus on extending the scalability and ...
... minutes before intercourse significantly postponed orgasm, study finds , THURSDAY, ... first potential treatment for premature ejaculation has proved effective in ... , PSD502 -- which combines the drugs lidocaine and prilocaine ... intercourse. , The study of men in Canada, Poland and ...
... ... its 9th Annual Conference on Contemporary Pharmacovigilance and Risk Management Strategies from January 10-13, ... ... will host its 9th Annual Conference on Contemporary Pharmacovigilance and Risk Management ...
... MELVILLE, N.Y., Nov. 19 Long Island IVF, a full ... patients achieve successful pregnancies, is now offering a new program ... treatment. Through this program and a partnership with In Vitro ... amount of money couples pay for their comprehensive treatment plans ...
... Washington State Nurses Association (WSNA), representing more than 1,600 ... press conference today to highlight serious concerns about the safety ... this H1N1 pandemic. In response to numerous reports from ... hospital fully comply with CDC guidelines on H1N1 prevention and ...
Cached Medicine News:Health News:New National Nurse Talk Radio Show Takes Off with Humor, Health, and a Voice for the Patient Advocate 2Health News:New National Nurse Talk Radio Show Takes Off with Humor, Health, and a Voice for the Patient Advocate 3Health News:Duplicate File Detective v3.0 Provides Enterprise-Grade Duplicate File Management 2Health News:Spray May Delay Ejaculation 2Health News:DIA Safety Conference To Explore Solutions To Challenges Facing Pharmaocovigilance And Risk Management Strategies 2Health News:DIA Safety Conference To Explore Solutions To Challenges Facing Pharmaocovigilance And Risk Management Strategies 3Health News:Long Island IVF to Offer IVF Financial Share Program, Limiting Costs and Providing Refunds if IVF is Not Successful 2Health News:Respirators and H1N1 Information Distributed to Registered Nurses at Sacred Heart Medical Center Out of Concern for Nurse and Patient Safety 2Health News:Respirators and H1N1 Information Distributed to Registered Nurses at Sacred Heart Medical Center Out of Concern for Nurse and Patient Safety 3
(Date:1/23/2015)... MYERS, Fla. , Jan. 23, 2015  Today the ... of Novartis, Bexsero® for the prevention of serogroup ... 25. Bexsero and Pfizer,s vaccine Trumenba®, which received FDA ... helping prevent this devastating disease. "I ...
(Date:1/23/2015)... 23, 2015 A lot of discussion in the medical ... certain illnesses, injuries, or conditions. As medical science advances, doctors ... with ones that they consider to be more cutting edge. ... one textbook method of treatment that stands out as the ...
(Date:1/23/2015)... Jan. 23, 2015  The Partnership to Fight Chronic Disease (PFCD) released ... care leaders and a new study analyzing the impact of increased ... a nationwide coalition working to educate policy makers and the public ... Capitol was focused on how the Iowa ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2No One-Size-Fits-All Remedy for Hernia Correction 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3
... SAN FRANCISCO, Calif., May 10, 2011 Janssen ... Alzheimer,s Immunotherapy Program, Pfizer Inc., is pleased to ... health organization in Alzheimer,s care, support and research, ... Summits Climb for Alzheimer,s: Memories are Everything ...
... Vista Partners announced today that it ... (AMEX: HBP, TSX: HBP) ("the Company") with a twelve ... at Vista Partners stated, "The Company is developing products ... and most advanced, Interferon alpha-2b, is a potent immuno-modulatory ...
Cached Medicine Technology:Alzheimer's Association Salutes Advocate and Mountaineer Now Climbing Everest as Part of The 7 Summits Climb for Alzheimer's 2Alzheimer's Association Salutes Advocate and Mountaineer Now Climbing Everest as Part of The 7 Summits Climb for Alzheimer's 3Alzheimer's Association Salutes Advocate and Mountaineer Now Climbing Everest as Part of The 7 Summits Climb for Alzheimer's 4Vista Partners Initiates Coverage on Helix BioPharma Corporation; Target Price $6.20 2
... management software - was designed by ... improvement tool helps diabetes care providers ... bridges medicine with technology by providing ... information technology product. This diabetes ...
... making decisions about insulin dosages and other ... are guided by data from blood glucose ... the patterns that can be seen by ... the data is presented in organized and ...
... The Ex-PRESS ... that provides a simplified,method of ... open angle glaucoma.,Similar to trabeculectomy, ... pressure,by diverting the aqueous humor ...
... StabilEyes CTR is a device designed for ... during cataract removal surgery. It provides secondary ... compromised zonules. The CTR is a uniplanar, ... ultraviolet light absorbing polymethylmethacrylate (PMMA) with one ...
Medicine Products: